5 unknown, 3 completed, 1 recruiting, 1 withdrawn. 5 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 2, Unknown 2, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Amniocentesis: new trials by email Literature Review of Amniocentesis trials Research Report on Amniocentesis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TAILORED Therapeutic Regime in Patients With Preterm Premature Rupture Of Membranes to Prolong Pregnancy, Improve Maternal and Neonatal Outcomes, and Reduce Antibiotic Burden Tailored antibiotic and steroid therapy based on the IL-6 value in amniotic fluid obtained by amniocentesis in patients with premature rupture of membranes, Antenatal steroids administration, Neuroprotection - Preterm Premature Rupture of Membranes (PPROM) | Phase 3 | Recruiting | The Central and Eastern European Gynecologic Oncology Group | 138 | 2025-05-01 | 2026-06-18 |
| Progesterone Levels and Pregnancy Results amniocentesis - Pregnancy Complications, Pregnancy Preterm | Unknown | Ufuk University | 100 | 2021-12-01 | 2021-11-02 | |
| Premature Rupture Membranes and tPTL: a Personalised Approach (PROMPT) Amniocentesis, Routine care without amniocentesis - Preterm Rupture of Membranes, Threatened Preterm Labor | Not applicable | Unknown | Chelsea and Westminster NHS Foundation Trust | 276 | 2021-09-01 | 2021-08-18 |
| Metals/Vitamins Levels in NTD Amniocentesis - Neural Tube Defects | Unknown | Cengiz Gokcek Women's and Children's Hospital | 140 | 2020-08-25 | 2021-08-31 | |
| Development of Potential Biomarkers for Foetal Brain Development After Congenital CMV Infection amniocentesis - Cytomegalovirus Infections, Neurologic Dysfunction | Not applicable | Unknown | Universitaire Ziekenhuizen KU Leuven | 20 | 2017-07-01 | 2017-06-15 |
| Electronic Nose and Fetal Chromosomal Disorders observational study done only in women candidate for amniocentesis - Detecting Abnormal Fetal Karyotype by the Electronic Nose | Unknown | Rambam Health Care Campus | 500 | 2015-10-01 | 2015-10-19 | |
| Development of an Optimal Approach to Return of Results for Next-generation Sequencing for Prenatal Diagnosis Whole Genome Sequencing, Amniocentesis, Psychosocial assessment - Major Fetal Anomaly | Not applicable | Withdrawn | University of California, San Diego | 2014-10-01 | 2019-06-06 | |
| Local Anesthesia and Pain Perception During an Amniocentesis Local Anesthesia, Placebo Group - Pregnancy | Not applicable | Completed | University of Oklahoma | 76 | 2007-10-01 | 2021-02-03 |
| N-acetylcysteine in Intra-amniotic Infection/Inflammation amniocentesis, N-acetylcysteine or placebo - Labor, Premature, Preterm Premature Rupture of the Membranes | Phase 1 / Phase 2 | Completed | Ohio State University | 68 | 2006-10-01 | 2018-10-10 |
| Prenatal Testing: Amniocentesis Versus Transabdominal Chorionic Villus Sampling (TA CVS) Amniocentesis, Transabdominal chorionic villus sampling (TA CVS) - Pregnancy | Not applicable | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 6400 | 1996-09-01 | 2005-06-24 |
Preterm Premature Rupture of the Membranes (2) · Agnosia (1) · Chorioamnionitis (1) · Cytomegalovirus Infections (1) · Fetal Membranes, Premature Rupture (1) · Infections (1) · Inflammation (1) · Neural Tube Defects (1) · Neurologic Manifestations (1) · Obstetric Labor, Premature (1) · Pain (1) · Pregnancy Complications (1)
Cengiz Gokcek Women's and Children's Hospital (1) · Chelsea and Westminster NHS Foundation Trust (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Ohio State University (1) · Rambam Health Care Campus (1) · The Central and Eastern European Gynecologic Oncology Group (1) · Ufuk University (1) · Universitaire Ziekenhuizen KU Leuven (1) · University of California, San Diego (1) · University of Oklahoma (1)
United States (3) · Czechia (1) · Turkey (Türkiye) (1)
Andrew Elimian, MD (1) · Catalin S Buhimschi, MD, MBA (1) · Laird G. Jackson, M.D. (1) · Lisa Hui, MD, PhD (1)
PMID 25375307, PMID 27918138, PMID 28196803, PMID 31743503, PMID 5157500, PMID 7072456
R01HD032109 (1)