Breast Tumors: Clinical Trials

6 completed. 6 Phase 2.

By phase and status

Phase	Trials	Status
Phase 2	6	Completed 6

Follow Breast Tumors: new trials by email Literature Review of Breast Tumors trials Research Report on Breast Tumors

Trials (filtered) newest first · largest first

All 6 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Study of DS-8201a, an Antibody Drug Conjugate for Advanced Breast Cancer Patients, With Biomarkers Analysis DS-8201a - Breast Tumors	Phase 2	Completed	UNICANCER	186	2019-10-21	2025-06-12
Study to Compare Alisertib With Paclitaxel vs. Paclitaxel Alone in Metastatic or Locally Recurrent Breast Cancer Paclitaxel, Alisertib - Breast Cancer, Breast Carcinoma	Phase 2	Completed	US Oncology Research	169	2015-02-12	2024-10-09
A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer Letrozole, palbociclib - Breast Cancer, Breast Carcinoma	Phase 2	Completed	NSABP Foundation Inc	307	2015-01-01	2022-01-13
Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors Lapatinib - Brain Metastases, Lung Tumors	Phase 2	Completed	Hellenic Cooperative Oncology Group	82	2010-10-01	2014-12-31
Study of Pralatrexate in Female Patients With Previously-treated Breast Cancer Pralatrexate Injection, Vitamin B12, Folic Acid - Breast Cancer, Breast Tumors	Phase 2	Completed	Acrotech Biopharma Inc.	22	2010-03-01	2020-01-07
QUILT-2.015: A Study of AMG 479 With Exemestane or Fulvestrant in Postmenopausal Women With Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer AMG 479, Placebo - Breast Cancer, Breast Tumors	Phase 2	Completed	NantCell, Inc.	156	2008-03-27	2024-09-19

Narrower conditions

Breast Neoplasms (6)  ·  Neoplasm Metastasis (2)  ·  Brain Neoplasms (1)  ·  Lung Neoplasms (1)  ·  Triple Negative Breast Neoplasms (1)

Broader conditions

Breast Diseases (6)  ·  Neoplasms (6)  ·  Neoplasms by Site (6)  ·  Skin Diseases (6)  ·  Skin and Connective Tissue Diseases (6)  ·  Neoplastic Processes (2)  ·  Pathologic Processes (2)  ·  Pathological Conditions, Signs and Symptoms (2)  ·  Brain Diseases (1)  ·  Central Nervous System Diseases (1)  ·  Central Nervous System Neoplasms (1)  ·  Lung Diseases (1)  ·  Nervous System Diseases (1)  ·  Nervous System Neoplasms (1)  ·  Respiratory Tract Diseases (1)

Interventions

10-propargyl-10-deazaaminopterin (1)  ·  Albumin-Bound Paclitaxel (1)  ·  Folic Acid (1)  ·  Lapatinib (1)  ·  Letrozole (1)  ·  MLN 8237 (1)  ·  Paclitaxel (1)  ·  Vitamin B 12 (1)  ·  ganitumab (1)  ·  palbociclib (1)  ·  trastuzumab deruxtecan (1)

Sponsors

Acrotech Biopharma Inc. (1)  ·  Hellenic Cooperative Oncology Group (1)  ·  NSABP Foundation Inc (1)  ·  NantCell, Inc. (1)  ·  UNICANCER (1)  ·  US Oncology Research (1)

Countries

United States (4)  ·  France (3)  ·  Canada (2)  ·  United Kingdom (2)  ·  Australia (1)  ·  Czechia (1)  ·  Germany (1)  ·  Greece (1)  ·  Hungary (1)  ·  Ireland (1)  ·  Spain (1)  ·  Switzerland (1)

Top investigators

Christos Christodoulou, MD (1)  ·  Garry Weems, PharmD (1)  ·  Joyce A. O'Shaughnessy, MD (1)  ·  Norman Wolmark, MD (1)

Results publications

PMID 33877311, PMID 37488289

NIH funding

2008 (1), 2009 (1), 2018 (1)