2 completed, 2 not yet recruiting, 2 terminated, 1 recruiting. 8 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 2, Not yet recruiting 2, Terminated 2, Recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
Follow Bone Cysts: new trials by email Literature Review of Bone Cysts trials Research Report on Bone Cysts
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low-Intensity Pulsed Ultrasound as an Adjunctive Therapy for Bone Regeneration Following Jaw Cyst Enucleation Low-Intensity Pulsed Ultrasound - Jaw Cysts, Curettage | Phase 3 | Not yet recruiting | Sadam Elayah | 29 | 2025-10-22 | 2025-10-07 |
| Using of Bone Marrow Stem Cell Concentrate with Platelet Rich Fibrin and Bone Graft in Bone Reconstruction of Upper Jaw Bony Cystic Defects, Comparing with Platelet Rich Fibrin with Bone Graft Bone marrow stem cells concentrate , platelet rich fibrin , bone graft, platelet rich fibrin and bone graft - Maxillary Cyst | Phase 3 | Not yet recruiting | Cairo University | 22 | 2024-10-26 | 2024-10-29 |
| Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin Syndrome Patidegib Topical Gel, Patidegib Topical Gel with no active patidegib - Gorlin Syndrome | Phase 3 | Completed | Sol-Gel Technologies, Ltd. | 113 | 2024-03-17 | 2026-09-18 |
| Extension Study of Patidegib Topical Gel, 2% in Subjects With Gorlin Syndrome (Basal Cell Nevus Syndrome) Patidegib Topical Gel, 2% - Basal Cell Nevus Syndrome | Phase 3 | Terminated | Sol-Gel Technologies, Ltd. | 108 | 2020-06-03 | 2024-09-24 |
| Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome) Patidegib Topical Gel, 2%, Patidegib Topical Gel, Vehicle - Basal Cell Nevus Syndrome | Phase 3 | Completed | Sol-Gel Technologies, Ltd. | 174 | 2019-02-19 | 2024-07-03 |
| Simple Bone Cysts in Kids Curettage with puncture (C & P), Curette, Vitoss morsels - Bone Cyst | Phase 3 | Recruiting | The Hospital for Sick Children | 160 | 2015-03-01 | 2023-07-12 |
| Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin. verteporfin PDT - Basal Cell Carcinoma, Nevoid Basal Cell Carcinoma Syndrome | Phase 3 | Terminated | QLT Inc. | 2011-03-16 | ||
| Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS) LDE225B, Vehicle - Basal Cell Carcinoma | Phase 2 / Phase 3 | Withdrawn | Novartis Pharmaceuticals | 2017-05-05 |
Basal Cell Nevus Syndrome (5) · Carcinoma, Basal Cell (4) · Jaw Cysts (2) · Basal cell carcinoma, multiple (1)
Cysts (8) · Musculoskeletal Diseases (8) · Neoplasms (8) · Jaw Diseases (7) · Stomatognathic Diseases (7) · Bone Diseases (6) · Abnormalities, Multiple (5) · Bone Diseases, Developmental (5) · Carcinoma (5) · Congenital Abnormalities (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Genetic Diseases, Inborn (5) · Jaw Cysts (5) · Neoplasms by Histologic Type (5)
Bone Transplantation (1) · Curettage (1) · IPI-926 (1) · Punctures (1)
Sol-Gel Technologies, Ltd. (3) · Cairo University (1) · Novartis Pharmaceuticals (1) · QLT Inc. (1) · Sadam Elayah (1) · The Hospital for Sick Children (1)
United Kingdom (5) · Germany (4) · Italy (4) · Spain (4) · United States (4) · Belgium (3) · Canada (3) · France (3) · Netherlands (3) · Denmark (2) · Australia (1) · Czechia (1) · Finland (1) · Greece (1) · Switzerland (1)
Herma Neyndorff (1) · James G. Wright (1) · Sevan Hopyan (1)
PMID 11873920, PMID 28953676, PMID 32145206
2023 (1)