37 completed, 8 recruiting, 5 terminated, 4 unknown. 20 Not applicable, 19 Phase 2, 5 Phase 1, 5 Phase 3, 3 Phase 4.
Follow Odontogenic Cysts: new trials by email Literature Review of Odontogenic Cysts trials Research Report on Odontogenic Cysts
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Osteogenic Potential of Topical Metformin Gel on Cystic Jaw Defects For the Experimental Arm: 1% Metformin Gel, For the Comparator / Control Arm: Placebo Gel - Jaw Cysts, Metformin | Not applicable | Not yet recruiting | Fayoum University | 32 | 2026-10-30 | 2026-10-14 |
| Detection of Disease Marker Factors in Cyst Fluid cyst fluid examination - Biomarkers | Recruiting | Harran University | 25 | 2025-08-25 | 2025-09-12 | |
| Bone Regeneration Using PRF After Cyst Enucleation Autologous Platelet-Rich Fibrin (PRF), Conventional Surgical Management - Odontogenic Cyst, Jaw Cysts | Not applicable | Recruiting | Sana'a University | 20 | 2025-05-19 | 2026-02-20 |
| Clinical and Radiographic Characteristics and Outcomes of Guided Apicoectomy With Retrograde Mineral Trioxide Aggregate Filling for Periapical Cysts Guided Apicoectomy With Retrograde Mineral Trioxide Aggregate Filling - Periapical Cyst | Not applicable | Completed | Can Tho University of Medicine and Pharmacy | 42 | 2025-05-03 | 2026-07-24 |
| Patient Specific Implants (PSIs) for the Decompression of Odontogenic Cysts Preoperative Cone Beam Computed Tomography (CBCT) scan, Cystostomy, Histology to confirm the initial diagnosis - Odontogenic Cysts, Odontogenic Keratocyst | Recruiting | Semmelweis University | 20 | 2024-11-26 | 2026-04-24 | |
| Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery PBM treatment, PBM sham treatment, EMS - Apical Periodontitis, Endodontically Treated Teeth | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 90 | 2024-08-20 | 2026-08-17 |
| Effect of Targeted Endodontic Microsurgery on Quality of Life and Healing on Mandibular Molars Targeted Endodontic Microsurgery Using 3d Printed surgical guide using the patient's CBCT data, Conventional Endodontic Microsurgery with a free hand procedure using bur and CBCT analysis - Periapical Diseases, Periapical Periodontitis | Not applicable | Completed | Postgraduate Institute of Dental Sciences Rohtak | 62 | 2024-07-01 | 2026-09-17 |
| Examining the Effect of Different Filling Techniques on Healing in Lesional Teeth retrograde and orthograde root canal filling - Apical Cyst | Not applicable | Completed | TC Erciyes University | 60 | 2024-05-08 | 2026-09-30 |
| Bone Defects Reconstruction After Dentigerous Cyst Enucleation With Autogenous Demineralized Dentin Matrix- ADDM and Advanced Platelet-Rich Fibrin- A-PRF. Impacted third molar extraction, Advanced Platelet-Rich Fibrin (A-PRF), Mandibular dentigerous cyst enucleation - Impact Molar, Mandible Cyst | Not applicable | Active not recruiting | Jagiellonian University | 35 | 2024-04-04 | 2026-06-23 |
| Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin Syndrome Patidegib Topical Gel, Patidegib Topical Gel with no active patidegib - Gorlin Syndrome | Phase 3 | Completed | Sol-Gel Technologies, Ltd. | 113 | 2024-03-17 | 2026-09-18 |
| Volumetric Changes in Large Cystic Lesions Using Active Decompression and Distraction Sugosteogenesis vs Passive Decompression Active decompression - Odontogenic Cysts | Not applicable | Unknown | Radwa Hydar Ragab | 10 | 2024-03-01 | 2024-02-16 |
| Intravenous Dexamethasone on Postoperative Pain and Complications in Jaw Surgery Dexamethasone - Tooth Extraction Status Nos, Cysts Dental | Phase 4 | Completed | Selcuk University | 60 | 2024-01-01 | 2026-06-29 |
| Reproductive Options in Inherited Skin Diseases Ichthyosis, Palmoplantar Keratoses | Enrolling by invitation | Maastricht University Medical Center | 650 | 2024-01-01 | 2025-05-18 | |
| Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling Qualitative interview - Quality of Life, Ichthyosis | Recruiting | Maastricht University Medical Center | 25 | 2024-01-01 | 2025-05-18 | |
| PRF Membrane and Recovery After Periapical Surgery: A 3D Imaging Study Platelet-Rich Fibrin (PRF) Membrane - Periapical Diseases, Radicular Cyst | Not applicable | Completed | Semmelweis University | 20 | 2023-09-04 | 2024-12-18 |
| Usage of 5-fluorouracil and Carnoy's Solution in Surgical Treatment of Odontogenic Keratocysts Enucleation, incisional biopsy, Application of 5-fluorouracil - Odontogenic Keratocyst | Phase 4 | Enrolling by invitation | University of Belgrade | 50 | 2023-06-10 | 2026-04-13 |
| Nevoid Basal Cell Carcinomas in Gorlin Syndrome Active surveillance - Basal Cell Carcinoma, Gorlin Syndrome | Completed | Oslo University Hospital | 7 | 2023-06-01 | 2026-10-09 | |
| Risk-Adapted Treatment Strategies for Odontogenic Keratocysts: A Long-Term Randomized Clinical Trial Quantifying Recurrence Reduction Enucleation+ Peripheral Ostectomy+Carnoy's solution chemical cauterization (E+CS + PO), Decompression/ marsupialization (D/M), Enucleation (E) - Odontogenic Cysts | Not applicable | Completed | Qassim University | 50 | 2023-02-24 | 2026-01-07 |
| Recurrence of Odontogenic Keratocyst Topical Application of 5-Fluorouracil - Odontogenic Cyst | Not applicable | Completed | Tanta University | 48 | 2022-12-02 | 2025-02-10 |
| Adjunctive Methods In Treatment Of Odontogenic Keratocyst Enucleation, cyst enucleation - Keratocysts of the Jaw | Not applicable | Completed | Tanta University | 20 | 2022-10-02 | 2025-02-12 |
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Basal Cell Nevus Syndrome (35) · Carcinoma, Basal Cell (23) · Radicular Cyst (11) · Periapical Diseases (4) · Periapical Periodontitis (4) · Skin Neoplasms (4) · Periapical Granuloma (3) · Tuberous Sclerosis (3) · Xeroderma Pigmentosum (3) · Albinism (2) · Birt-Hogg-Dube Syndrome (2) · Cutis Laxa (2) · Dentigerous Cyst (2) · Ectodermal Dysplasia (2)
Bone Cysts (61) · Cysts (61) · Jaw Diseases (61) · Musculoskeletal Diseases (61) · Stomatognathic Diseases (61) · Jaw Cysts (59) · Neoplasms (59) · Neoplasms by Histologic Type (36) · Abnormalities, Multiple (35) · Bone Diseases (35) · Bone Diseases, Developmental (35) · Congenital Abnormalities (35) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (35) · Genetic Diseases, Inborn (35)
HhAntag691 (5) · sonidegib (4) · Eye Enucleation (3) · IPI-926 (3) · gusacitinib (3) · 1-phenyl-3,3-dimethyltriazene (2) · Aminolevulinic Acid (2) · Apicoectomy (2) · Cystostomy (2) · Decompression (2) · Drug Evaluation (2) · Photochemotherapy (2) · Radionuclide Imaging (2) · tazarotene (2) · BMS-833923 (1)
UCSF Benioff Children's Hospital Oakland (6) · Novartis Pharmaceuticals (4) · Sol-Gel Technologies, Ltd. (4) · Ascend Biopharmaceuticals Ltd (3) · Maastricht University Medical Center (3) · Semmelweis University (3) · Ain Shams University (2) · PellePharm, Inc. (2) · Tanta University (2) · Akdeniz University (1) · Alexandria University (1) · Anne Chang (1) · Cairo University (1) · Can Tho University of Medicine and Pharmacy (1) · Case Comprehensive Cancer Center (1)
United States (22) · Egypt (8) · Netherlands (6) · United Kingdom (6) · Belgium (5) · Canada (5) · Germany (5) · Italy (4) · Spain (4) · Turkey (Türkiye) (4) · Australia (3) · Austria (3) · France (3) · Hungary (3) · Denmark (2)
Ervin Epstein, MD (5) · Antoni Gostynski, MD, PhD (2) · David R. Bickers, MD (2) · Edward V. Maytin, MD, PhD (2) · Gregory Siller (2) · Mohamed K Allam, Ass prof (2) · Allen E. Bale, MD (1) · Anna Bar (1) · Anne Lynn Chang (1) · Anne Lynn Chang, MD (1) · Brian L Schmidt, DDS, MD, PhD (1) · Clement Leong (1) · Clement Leong, Ph.D (1)
PMID 12424446, PMID 12796876, PMID 15170272, PMID 18038077, PMID 21194990, PMID 22670904, PMID 24441673, PMID 24576437, PMID 24623282, PMID 25631867, PMID 26250795, PMID 26428611, PMID 26692930, PMID 27838224, PMID 28377093, PMID 28809378, PMID 29175429, PMID 3127567, PMID 31735221, PMID 33663899, PMID 34324108, PMID 34703121, PMID 34749963, PMID 36116543, PMID 39204985, PMID 39548448, PMID 41176605
R01CA109584 (2), 2015 (1), 2023 (1), P30CA124435 (1), U10CA098543 (1), U10CA180886 (1), U19CA081888 (1)