2 completed, 2 terminated, 1 active not recruiting. 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 2, Terminated 2, Active not recruiting 1 |
Follow Ataxia Telangiectasia: new trials by email Literature Review of Ataxia Telangiectasia trials Research Report on Ataxia Telangiectasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Pivotal Study of N-Acetyl-L-Leucine on Ataxia-Telangiectasia (A-T) N-Acetyl-L-Leucine, Placebo - Ataxia-Telangiectasia, Ataxia-Telangiectasia (A-T) | Phase 3 | Active not recruiting | IntraBio Inc | 60 | 2025-03-18 | 2025-07-03 |
| Open-Label Extension of EryDex Study IEDAT-04-2022 Dexamethasone sodium phosphate - Ataxia Telangiectasia | Phase 3 | Terminated | Quince Therapeutics S.p.A. | 101 | 2024-12-11 | 2026-05-05 |
| Evaluate the Neurological Effects of EryDex on Subjects With A-T Dexamethasone sodium phosphate, Placebo - Ataxia Telangiectasia | Phase 3 | Completed | Quince Therapeutics S.p.A. | 105 | 2024-06-24 | 2026-04-30 |
| Extension Treatment Using EryDex System in Patients With AT Who Participated in the ATTeST-IEDAT-02-2015 Study EryDex System - Ataxia Telangiectasia, Genetic Syndrome | Phase 3 | Terminated | Quince Therapeutics S.p.A. | 104 | 2018-06-12 | 2024-10-08 |
| Conjugate Pneumococcal Vaccine in Ataxia Telangiectasia (AT) Conjugated pneumococcal vaccine (Prevenar) - Ataxia Telangiectasia (AT) | Phase 3 | Completed | Institute of Child Health | 30 | 2006-06-01 | 2008-04-11 |
Ataxia (5) · Brain Diseases (5) · Cardiovascular Diseases (5) · Central Nervous System Diseases (5) · Cerebellar Ataxia (5) · Cerebellar Diseases (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · DNA Repair-Deficiency Disorders (5) · Dyskinesias (5) · Immune System Diseases (5) · Immunologic Deficiency Syndromes (5) · Metabolic Diseases (5) · Nervous System Diseases (5) · Neurocutaneous Syndromes (5) · Neurologic Manifestations (5)
dexamethasone 21-phosphate (2) · Heptavalent Pneumococcal Conjugate Vaccine (1) · IB1001 (1) · acetylleucine (1)
Quince Therapeutics S.p.A. (3) · Institute of Child Health (1) · IntraBio Inc (1)
United Kingdom (5) · Germany (4) · Spain (4) · United States (4) · Italy (3) · Norway (3) · Poland (3) · Switzerland (3) · Denmark (2) · Australia (1) · Belgium (1) · India (1) · Slovakia (1) · Tunisia (1)
Dirk Thye, MD (2) · Guenter R Janhofer, MD, PhD (1)
PMID 39917433, PMID 42309084, PMID 42600624
2018 (1)