14 terminated. 14 Phase 1, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 14 | Terminated 14 |
| Phase 2 | 8 | Terminated 8 |
Follow Anemia, Aplastic: new trials by email Literature Review of Anemia, Aplastic trials Research Report on Anemia, Aplastic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy REGN7257 - Severe Aplastic Anemia (SAA) | Phase 1 | Terminated | Regeneron Pharmaceuticals | 17 | 2021-01-13 | 2026-06-22 |
| The Use of Trifluoperazine in Transfusion Dependent DBA Trifluoperazine - Diamond Blackfan Anemia, Pure Red Cell Aplasia | Phase 1 / Phase 2 | Terminated | Adrianna Vlachos, MD | 2 | 2019-09-13 | 2022-12-14 |
| Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study Rimiducid, rivogenlecleucel - Acute Lymphoblastic Leukemia, Leukemia, Acute Myeloid (AML), Child | Phase 1 / Phase 2 | Terminated | Bellicum Pharmaceuticals | 187 | 2017-01-01 | 2023-09-26 |
| Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases BPX-501 and Rimiducid - Primary Immune Deficiency Disorders, Hemophagocytic Lymphohistiocytosis | Phase 1 | Terminated | Bellicum Pharmaceuticals | 1 | 2015-02-01 | 2024-03-25 |
| Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant BPX-501 T cells, Rimiducid - Acute Lymphoblastic Leukemia, Leukemia, Acute Myeloid (AML), Child | Phase 1 / Phase 2 | Terminated | Bellicum Pharmaceuticals | 187 | 2014-04-01 | 2023-09-29 |
| Gene Therapy for Fanconi Anemia Bone Marrow Aspiration, Filgrastim, Genetically Engineered Hematopoietic Stem Progenitor Cells - Fanconi Anemia | Phase 1 | Terminated | Fred Hutchinson Cancer Center | 3 | 2012-02-22 | 2024-05-17 |
| Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia Sotatercept, Sotatercept with prednisone boost - Diamond Blackfan Anemia | Phase 1 / Phase 2 | Terminated | Northwell Health | 19 | 2012-01-01 | 2023-03-17 |
| Alefacept in Patients With Relapsed/Refractory Aplastic Anemia Alefacept - Aplastic Anemia | Phase 1 | Terminated | The Cleveland Clinic | 4 | 2011-05-01 | 2018-01-26 |
| Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis Congenita danazol - Fanconi Anemia, Dyskeratosis Congenita | Phase 1 / Phase 2 | Terminated | Boston Children's Hospital | 5 | 2009-11-01 | 2019-02-19 |
| Treatment of Menorrhagia in Women With Thrombocytopenia Using Platelets or Platelets and Hormones Lo-Ovral Oral Contraceptive Pills, Placebo - sugar pill - Aplastic Anemia, Menorrhagia | Phase 1 / Phase 2 | Terminated | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1 | 2007-11-01 | 2013-07-19 |
| Cyclophosphamide, Antithymocyte Globulin, and Total-Body Irradiation in Treating Patients With Severe Aplastic Anemia Undergoing Umbilical Cord Blood Transplant total-body irradiation, cyclophosphamide, anti-thymocyte globulin - Aplastic Anemia | Phase 1 | Terminated | Fred Hutchinson Cancer Center | 30 | 2006-02-01 | 2011-01-05 |
| Stem Cell Transplantation for Fanconi Anemia Hematopoietic Stem Cell Transplant, Thymic Shielding During Radiation, Total Body Irradiation - Fanconi Anemia | Phase 1 / Phase 2 | Terminated | Masonic Cancer Center, University of Minnesota | 16 | 2004-03-01 | 2019-08-26 |
| Use of Rft5-Dga to Deplete Alloreactive Cells for Pts With Fanconi Anemia After Haploidentical SCT CD34 selected haploidentical PBSCT, Fludarabine, T cell infusion - FANCONI ANEMIA | Phase 1 | Terminated | Baylor College of Medicine | 1 | 2002-03-01 | 2014-03-04 |
| Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia CAMPATH-1H, Anti-CD45, Fludarabine - Fanconi Anemia, Severe Aplastic Anemia | Phase 1 / Phase 2 | Terminated | Baylor College of Medicine | 5 | 2001-07-01 | 2018-05-24 |
Fanconi Anemia (8) · Anemia, Diamond-Blackfan (5) · Anemia (3) · Anemia, Sickle Cell (3) · Hemoglobinopathies (3) · Primary Immunodeficiency Diseases (3) · Thalassemia (3) · Cytopenia (2) · Dyskeratosis Congenita (2) · Hematologic Neoplasms (2) · Leukemia (2) · Leukemia, Myeloid, Acute (2) · Lymphoma, Non-Hodgkin (2) · Myelodysplastic Syndromes (2)
Bone Marrow Diseases (14) · Hematologic Diseases (14) · Hemic and Lymphatic Diseases (14) · Bone Marrow Failure Disorders (13) · Anemia (11) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Genetic Diseases, Inborn (10) · Anemia, Hypoplastic, Congenital (9) · Congenital Bone Marrow Failure Syndromes (9) · DNA Repair-Deficiency Disorders (8) · Nutritional and Metabolic Diseases (8) · Metabolic Diseases (7) · Anemia, Hemolytic (3) · Anemia, Hemolytic, Congenital (3)
AP 1903 reagent (2) · Alemtuzumab (2) · Cyclophosphamide (2) · Filgrastim (2) · Granulocyte Colony-Stimulating Factor (2) · Prednisone (2) · Whole-Body Irradiation (2) · fludarabine (2) · ACE-011 (1) · Alefacept (1) · Antilymphocyte Serum (1) · Bone Marrow Transplantation (1) · CF regimen (1) · Cord Blood Stem Cell Transplantation (1) · Cyclosporine (1)
Bellicum Pharmaceuticals (3) · Baylor College of Medicine (2) · Fred Hutchinson Cancer Center (2) · Adrianna Vlachos, MD (1) · Boston Children's Hospital (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Masonic Cancer Center, University of Minnesota (1) · Northwell Health (1) · Regeneron Pharmaceuticals (1) · The Cleveland Clinic (1)
United States (12) · Italy (2) · United Kingdom (2) · France (1) · South Korea (1)
Adrianna Vlachos, MD (2) · Ann Woolfrey (1) · Colin A Sieff, MB.BCh (1) · Hans-Peter Kiem (1) · Malcolm Brenner, M.B., Ph.D., (1) · Malcolm Brenner, MB, PhD (1) · Margaret MacMillan, MD (1) · Pamela Stratton, MD (1) · Ramon V. Tiu, M.D. (1)
2023 (1)