Amyloidosis: Clinical Trials

6 trials for Amyloidosis, newest first

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6 unknown. 6 Phase 1, 3 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 16Unknown 6
Phase 23Unknown 3

Follow Amyloidosis: new trials by email Literature Review of Amyloidosis trials Research Report on Amyloidosis

Trials (filtered) newest first · largest first

All 6 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
FKC288 for Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis
FKC288 - Light Chain Amyloidosis
Phase 1UnknownNanjing University School of Medicine122023-08-292023-11-15
Study of AT-02 in Healthy Volunteers and Subjects With Systemic Amyloidosis
AT-02, AT-02 (Placebo) - Amyloidosis; Systemic
Phase 1UnknownAttralus, Inc.1002022-09-012024-04-03
APG-2575 in Combination With Novel Therapeutic Regimens in Subjects With Relapsed or Refractory Multiple Myeloma
APG-2575+ Pd, APG-2575 + DRd - Multiple Myeloma, Amyloidosis
Phase 1 / Phase 2UnknownAscentage Pharma Group Inc.1082021-12-232023-10-25
Study of the Safety and Efficacy of STI-6129 in Patients With Relapsed or Refractory Systemic AL Amyloidosis
STI-6129 - Light Chain (AL) Amyloidosis
Phase 1 / Phase 2UnknownSorrento Therapeutics, Inc.602021-04-012023-01-17
Antibiotics Against Amyloid Angiopathy
Minocycline, Placebo - Cerebral Amyloid Angiopathy
Phase 1 / Phase 2UnknownLeiden University Medical Center602020-12-022023-01-11
Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer
sargramostim, amifostine trihydrate, carboplatin - Chronic Myeloproliferative Disorders, Drug/Agent Toxicity by Tissue/Organ
Phase 1UnknownThe Cleveland Clinic301997-11-012013-12-19

Narrower conditions

Immunoglobulin Light-chain Amyloidosis (3)  ·  Multiple Myeloma (2)  ·  Blast Crisis (1)  ·  Burkitt Lymphoma (1)  ·  Cerebral Amyloid Angiopathy (1)  ·  Drug-Related Side Effects and Adverse Reactions (1)  ·  Hodgkin Disease (1)  ·  Immunoblastic Lymphadenopathy (1)  ·  Leukemia (1)  ·  Leukemia, Biphenotypic, Acute (1)  ·  Leukemia, Hairy Cell (1)  ·  Leukemia, Large Granular Lymphocytic (1)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (1)  ·  Leukemia, Myeloid, Accelerated Phase (1)

Broader conditions

Metabolic Diseases (6)  ·  Nutritional and Metabolic Diseases (6)  ·  Proteostasis Deficiencies (6)  ·  Immune System Diseases (4)  ·  Immunoproliferative Disorders (4)  ·  Lymphoproliferative Disorders (4)  ·  Neoplasms (4)  ·  Neoplasms by Histologic Type (4)  ·  Paraproteinemias (4)  ·  Cardiovascular Diseases (3)  ·  Neoplasms, Plasma Cell (3)  ·  Vascular Diseases (3)  ·  Blood Protein Disorders (2)  ·  Hematologic Diseases (2)

Interventions

Amifostine (1)  ·  Carboplatin (1)  ·  Cyclophosphamide (1)  ·  Dexamethasone (1)  ·  GTP Cyclohydrolase (1)  ·  Lisaftoclax (1)  ·  Minocycline (1)  ·  sargramostim (1)

Sponsors

Ascentage Pharma Group Inc. (1)  ·  Attralus, Inc. (1)  ·  Leiden University Medical Center (1)  ·  Nanjing University School of Medicine (1)  ·  Sorrento Therapeutics, Inc. (1)  ·  The Cleveland Clinic (1)

Countries

United States (4)  ·  Australia (1)  ·  China (1)  ·  Netherlands (1)

Top investigators

Anita D'Souza, MD (1)  ·  George Thomas Budd, MD (1)  ·  Jeffrey Zonder, MD (1)  ·  Michael Rosenzweig, MD (1)  ·  Vaishali Sanchorawala, MD (1)  ·  Xianghua Huang, MD (1)  ·  Yifan Zhai, MD, PhD (1)

Results publications

PMID 37277877, PMID 41920709

NIH funding

2019 (1)