5 completed, 4 recruiting, 4 terminated, 3 active not recruiting. 6 Not applicable, 6 Phase 1, 6 Phase 2, 1 Phase 3.
Follow Advanced Lung Carcinoma: new trials by email Literature Review of Advanced Lung Carcinoma trials Research Report on Advanced Lung Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BBO-11818 in Adult Subjects With KRAS Mutant Cancer BBO-11818, Pembrolizumab, Platinum chemotherapy (cisplatin or carboplatin) - Non-Small Cell Lung Cancer, NSCLC | Phase 1 | Recruiting | TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) | 665 | 2025-03-31 | 2026-06-02 |
| Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer Olanzapine, Placebo Administration, Questionnaire Administration - Advanced Malignant Solid Neoplasm, Advanced Biliary Tract Carcinoma | Phase 2 | Recruiting | OHSU Knight Cancer Institute | 66 | 2024-07-17 | 2026-07-16 |
| Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer BBO-8520, Pembrolizumab, BBO-10203 - Non-small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer | Phase 1 | Recruiting | TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) | 350 | 2024-05-22 | 2026-09-03 |
| Exercise in Patients With Advanced Non-small Cell Lung Cancer Exercise intervention - Advanced Lung Carcinoma, First Line Treatment | Not applicable | Unknown | University Hospital, Essen | 104 | 2024-05-01 | 2024-04-18 |
| At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer Clinical Encounter, Home Health Encounter, Quality-of-Life Assessment - Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma | Phase 2 | Recruiting | Mayo Clinic | 220 | 2023-08-23 | 2026-04-20 |
| A Biomarker Screening Protocol for Participants With Solid Tumors Triple Negative Breast Cancer, Non-small Cell Lung Cancer | Terminated | Lyell Immunopharma, Inc. | 10 | 2023-05-19 | 2025-07-01 | |
| Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations silevertinib (BDTX-1535) monotherapy - Non-Small Cell Lung Cancer, Advanced Non-Small Cell Squamous Lung Cancer | Phase 1 / Phase 2 | Active not recruiting | Black Diamond Therapeutics, Inc. | 200 | 2022-03-31 | 2026-07-22 |
| A Study to Investigate LYL797 in Adults With Solid Tumors LYL797 - Triple Negative Breast Cancer, TNBC - Triple-Negative Breast Cancer | Phase 1 | Terminated | Lyell Immunopharma, Inc. | 57 | 2022-03-29 | 2025-07-01 |
| A Clinical Study of TQB3616 Capsules Combined With Anlotinib Hydrochloride Capsules or Standard Chemotherapy Second-line and Above in the Treatment of Advanced Lung Cancer TQB3616 capsules, Anlotinib Hydrochloride capsules, Irinotecan Hydrochloride for Injection - Advanced Lung Carcinoma | Phase 2 | Terminated | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 21 | 2021-08-18 | 2026-04-13 |
| A Biobehavioral/Cognitive Treatment for Stress, Depression, and Anxiety in Patients With Stage IV Lung Cancer Behavioral, Psychological or Informational Intervention, Biospecimen Collection, Electronic Health Record Review - Advanced Lung Carcinoma, Metastatic Lung Carcinoma | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 30 | 2021-06-01 | 2023-10-23 |
| Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies Anti-CTLA4 Monoclonal Antibody BMS-986218, Nivolumab, Stereotactic Body Radiation Therapy - Advanced Lung Carcinoma, Advanced Malignant Solid Neoplasm | Phase 1 / Phase 2 | Terminated | M.D. Anderson Cancer Center | 13 | 2021-03-29 | 2026-03-03 |
| A Nurse-Led Intervention for Fear of Progression in Advanced Cancer Educational Intervention - Advanced Lung Carcinoma, Metastatic Malignant Female Reproductive System Neoplasm | Not applicable | Active not recruiting | City of Hope Medical Center | 42 | 2021-03-15 | 2026-10-26 |
| BeWell360-CG Care Model: Health and Wellness Coaching to Support Caregivers of Patients Living With Advanced Lung Cancers Best Practice, Educational Intervention, Health Promotion and Education - Advanced Lung Carcinoma, Stage III Lung Cancer AJCC v8 | Not applicable | Completed | Mayo Clinic | 55 | 2021-02-03 | 2025-10-14 |
| Efficacy and Safety of First-line Anti-PD-1/PD-L1 Monoclonal Antibody in Combination With Chemotherapy and Bronchoscopy-assisted Interventional Therapy in Patients With Advanced Central Non-small Cell Lung Cancer Chemoimmunotherapy (CIT): Sintilimab + Platinum-Based Doublet Chemotherapy - Advanced Lung Carcinoma, Non-small Cell Lung Cancer | Phase 2 / Phase 3 | Completed | Shanghai Pulmonary Hospital, Shanghai, China | 33 | 2021-01-20 | 2026-07-21 |
| Resiliency Among Older Adults Receiving Lung Cancer Treatment Physical Therapy, Quality-of-Life Assessment, Questionnaire Administration - Advanced Lung Carcinoma, Extensive Stage Lung Small Cell Carcinoma | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 18 | 2020-01-22 | 2023-11-15 |
| Local Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer Brigatinib, Local Consolidation Therapy - Advanced Lung Carcinoma, ALK Gene Rearrangement | Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 35 | 2018-12-18 | 2025-11-03 |
| Conquer Fear SUPPORT Intervention in Supporting Patients With Stage III-IV Lung or Gynecologic Cancer Psychosocial Care Conquer Fear Support intervention (psychoeducation, attention training, worry management, and detached mindfulness components), Questionnaire Administration - Advanced Lung Carcinoma, Malignant Female Reproductive System Neoplasm | Not applicable | Completed | City of Hope Medical Center | 39 | 2018-11-13 | 2026-10-28 |
Lung Neoplasms (11) · Carcinoma, Non-Small-Cell Lung (8) · Neoplasm Metastasis (4) · Breast Neoplasms (2) · Carcinoma, Ovarian Epithelial (2) · Colorectal Neoplasms (2) · Endometrial Neoplasms (2) · Fallopian Tube Neoplasms (2) · Ovarian Neoplasms (2) · Recurrence (2) · Triple Negative Breast Neoplasms (2) · Adrenal Gland Neoplasms (1) · Anorexia (1) · Brain Neoplasms (1) · Cachexia (1)
Neoplasms (15) · Neoplasms by Site (15) · Lung Diseases (14) · Respiratory Tract Diseases (14) · Respiratory Tract Neoplasms (14) · Thoracic Neoplasms (14) · Bronchial Neoplasms (8) · Carcinoma, Bronchogenic (8) · Pathological Conditions, Signs and Symptoms (5) · Neoplasms by Histologic Type (4) · Neoplastic Processes (4) · Pathologic Processes (4) · Carcinoma (3) · Digestive System Diseases (3) · Digestive System Neoplasms (3)
Early Intervention, Educational (2) · Educational Status (2) · Methods (2) · pembrolizumab (2) · 130-nm albumin-bound paclitaxel (1) · Carboplatin (1) · Cetuximab (1) · Cisplatin (1) · Gemcitabine (1) · Health Promotion (1) · Home Care Services (1) · House Calls (1) · Injections (1) · Irinotecan (1) · Nivolumab (1)
City of Hope Medical Center (2) · Lyell Immunopharma, Inc. (2) · M.D. Anderson Cancer Center (2) · Mayo Clinic (2) · Ohio State University Comprehensive Cancer Center (2) · TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) (2) · Black Diamond Therapeutics, Inc. (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · OHSU Knight Cancer Institute (1) · Shanghai Pulmonary Hospital, Shanghai, China (1) · University Hospital, Essen (1)
United States (14) · Australia (2) · China (2) · Canada (1) · Denmark (1) · Germany (1) · Spain (1)
Jackie Walling, MBChB, PhD (2) · Anne Reb (1) · Anne Reb, NP, PhD (1) · Barbara Andersen, PhD (1) · Carolyn J Presley, MD, MHS (1) · Eric Roeland, M.D., FAAHPM, FASCO (1) · James Welsh (1) · Maisha T. Robinson, MD (1) · Mitra Tewes, PD. Dr. (1) · Moain Abu Dabrh, MB, BCh (1) · Roxana S. Dronca, MD (1) · Yasir Y Elamin, MD (1)
P30CA033572 (1), P30CA069533 (1), R03AG064374 (1)