Adenocarcinoma of the Lung: Clinical Trials

21 completed, 6 terminated, 3 unknown, 2 withdrawn. 18 Phase 2, 8 Phase 1, 5 Phase 3, 2 Not applicable, 1 Early Phase 1.

By phase and status

Phase	Trials	Status
Phase 2	18	Completed 14, Terminated 2, Unknown 1, Withdrawn 1
Phase 1	8	Completed 4, Terminated 2, Withdrawn 2
Phase 3	5	Completed 5
Not applicable	2	Active not recruiting 1, Completed 1
Early Phase 1	1	Terminated 1

Follow Adenocarcinoma of the Lung: new trials by email Literature Review of Adenocarcinoma of the Lung trials Research Report on Adenocarcinoma of the Lung

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Clinical Study of Camrelizumab Combined With APatinib and Albumin Paclitacxel in Patients With Advanced Lung Adenocarcinoma Camrelizumab, Albumin Paclitacxel, Apatinib - Adenocarcinoma of the Lung	Phase 2	Unknown	Hunan Cancer Hospital	63	2020-08-26	2022-12-02
Study of Nivolumab in Combination With GM.CD40L Vaccine in Adenocarcinoma of the Lung Nivolumab, GM.CD40L Vaccine - Lung Cancer, Adenocarcinoma of the Lung	Phase 1 / Phase 2	Withdrawn	H. Lee Moffitt Cancer Center and Research Institute		2018-07-01	2019-09-09
Feasibility and Safety of Nintedanib in Combination With Nivolumab in Pretreated Patients With Advanced or Metastatic NSCLC of Adenocarcinoma Histology nintedanib-nivolumab combination therapy - Adenocarcinoma of the Lung	Phase 1 / Phase 2	Completed	AIO-Studien-gGmbH	56	2018-05-25	2024-02-06
Single Agent Chemotherapy +/- Nivolumab in Patients With Advanced Squamous or Non-squamous NSCLC With Primary Resistance to Prior PD-1 or PDL-1 Inhibitor Docetaxel, Nivolumab, Gemcitabine - Non-Squamous Non-Small Cell Lung Cancer (NSCLC), Adenocarcinoma of the Lung	Phase 2	Terminated	Nasser Hanna, M.D.	3	2017-01-27	2022-07-11
Circulating Tumor DNA in Patients at High Risk for Lung Cancer Cancer of the Lung, Lung Cancer		Terminated	Pathway Genomics	39	2016-06-01	2017-08-21
Icotinib for Completed Resected IB NSCLC With EGFR Mutation Icotinib - Lung Neoplasms, Squamous Cell Lung Cancer	Phase 2	Completed	Sun Yat-sen University	128	2015-01-01	2024-09-25
Telomere Biology in Early Adenocarcinoma of the Lung Adenocarcinoma of the Lung, Adenocarcinoma, Bronchiolo-Alveolar		Unknown	Meir Medical Center	100	2014-09-01	2014-09-12
Comparison of Different Types of Surgery in Treating Patients With Early-stage Non-small Cell Lung Cancer Stage IA Non-small Cell Lung Cancer, Adenocarcinoma of the Lung		Unknown	Capital Medical University	630	2014-09-01	2014-11-11
Radiation Therapy, Chemotherapy, and Soy Isoflavones in Treating Patients With Stage IIIA-IIIB Non-Small Cell Lung Cancer soy isoflavones, cisplatin, etoposide - Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer	Phase 1	Completed	Barbara Ann Karmanos Cancer Institute	11	2014-08-01	2020-11-23
S1300: Pemetrexed Disodium With or Without Crizotinib in Treating Patients With Stage IV Non-Small Cell Lung Cancer That Has Progressed After Crizotinib crizotinib, pemetrexed disodium, laboratory biomarker analysis - Adenocarcinoma of the Lung, Large Cell Lung Cancer	Phase 2	Terminated	SWOG Cancer Research Network	1	2014-08-01	2020-02-20
Phase I IGART Study Using Active Breathing Control and Simultaneous Boost for Patients With NSCLC Paclitaxel, image-guided adaptive radiation therapy, carboplatin - Adenocarcinoma of the Lung, Large Cell Lung Cancer	Phase 1	Withdrawn	Virginia Commonwealth University		2014-03-01	2015-03-19
Study of Ponatinib in Patients With Lung Cancer Preselected Using Different Candidate Predictive Biomarkers Ponatinib - Adenocarcinoma of the Lung, Extensive Stage Small Cell Lung Cancer	Phase 2	Completed	University of Colorado, Denver	171	2013-09-24	2022-02-11
Adherence to Survivorship Care Guidelines in Health Care Providers for Non-Small Cell Lung Cancer and Colorectal Cancer Survivor Care educational intervention, medical chart review - Adenocarcinoma of the Lung, Mucinous Adenocarcinoma of the Colon	Not applicable	Completed	Fox Chase Cancer Center	1440	2013-01-01	2017-04-06
Low-Dose Acetylsalicylic Acid in Treating Patients With Stage I-III Non-Small Cell Lung Cancer acetylsalicylic acid, laboratory biomarker analysis - Adenocarcinoma of the Lung, Recurrent Non-small Cell Lung Cancer	Early Phase 1	Terminated	Vanderbilt-Ingram Cancer Center	4	2012-10-01	2020-01-14
Study of AXL1717 Compared to Docetaxel to Treat Squamous Cell Carcinoma or Adenocarcinoma of the Lung AXL1717, Docetaxel - Non-small-cell Lung Cancer, Squamous Cell Carcinoma	Phase 2	Completed	Axelar AB	100	2011-12-01	2013-12-05
A Safety and Efficacy Study of Farletuzumab in Participants With Adenocarcinoma of the Lung Farletuzumab, Placebo, Carboplatin - Adenocarcinoma of the Lung	Phase 2	Completed	Morphotek	130	2011-06-27	2020-08-20
Hsp90 Inhibitor AUY922 and Erlotinib Hydrochloride in Treating Patients With Stage IIIB-IV Non-Small Cell Lung Cancer erlotinib hydrochloride, Hsp90 inhibitor AUY922, laboratory biomarker analysis - Adenocarcinoma of the Lung, Non-small Cell Lung Cancer	Phase 1 / Phase 2	Completed	Northwestern University	38	2011-04-27	2019-09-11
Image-Guided Hypofractionated Radiation Therapy With Stereotactic Body Radiation Therapy Boost and Combination Chemotherapy in Treating Patients With Stage II-III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery hypofractionated radiation therapy, laboratory biomarker analysis, image-guided radiation therapy - Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer	Not applicable	Active not recruiting	Jonsson Comprehensive Cancer Center	29	2011-03-23	2026-02-25
Study of Vintafolide (MK-8109, EC145) in Participants With Progressive Adenocarcinoma of the Lung (MK-8109-008, EC-FV-03) Vintafolide, Etarfolatide - Adenocarcinoma of the Lung	Phase 2	Completed	Endocyte	43	2007-08-01	2015-02-27
Docetaxel, Cisplatin, Pegfilgrastim, and Erlotinib Hydrochloride in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer cisplatin, pegfilgrastim, erlotinib hydrochloride - Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer	Phase 2	Completed	Wake Forest University Health Sciences	45	2007-07-01	2018-06-29

Showing 20 of 33. Sign in to see all of them.

Narrower conditions

Adenocarcinoma of Lung (33)  ·  Carcinoma, Non-Small-Cell Lung (28)  ·  Adenocarcinoma, Bronchiolo-Alveolar (12)  ·  Lung Neoplasms (6)  ·  Adenocarcinoma (2)  ·  Bronchial Neoplasms (2)  ·  Neoplasms (2)  ·  Small Cell Lung Carcinoma (2)  ·  Carcinoma, Bronchogenic (1)  ·  Carcinoma, Squamous Cell (1)  ·  Colonic Neoplasms (1)  ·  Lung Diseases (1)  ·  Neoplasm Metastasis (1)  ·  Pleural Effusion, Malignant (1)  ·  Rectal Neoplasms (1)

Broader conditions

Carcinoma (33)  ·  Neoplasms by Histologic Type (33)  ·  Neoplasms by Site (33)  ·  Neoplasms, Glandular and Epithelial (33)  ·  Respiratory Tract Neoplasms (33)  ·  Thoracic Neoplasms (33)  ·  Adenocarcinoma (31)  ·  Neoplasms (31)  ·  Respiratory Tract Diseases (29)  ·  Lung Diseases (28)  ·  Carcinoma, Bronchogenic (27)  ·  Lung Neoplasms (27)  ·  Bronchial Neoplasms (26)  ·  Bronchial Diseases (2)  ·  Colonic Diseases (1)

Interventions

Paclitaxel (10)  ·  Carboplatin (9)  ·  Taxes (9)  ·  Cisplatin (6)  ·  Docetaxel (6)  ·  Radiotherapy (5)  ·  Erlotinib Hydrochloride (4)  ·  Pemetrexed (4)  ·  Radiation (4)  ·  Bevacizumab (3)  ·  Etoposide (3)  ·  Gefitinib (3)  ·  Bortezomib (2)  ·  Cetuximab (2)  ·  Nivolumab (2)

Sponsors

National Cancer Institute (NCI) (12)  ·  AIO-Studien-gGmbH (1)  ·  Axelar AB (1)  ·  Barbara Ann Karmanos Cancer Institute (1)  ·  Capital Medical University (1)  ·  Endocyte (1)  ·  Fox Chase Cancer Center (1)  ·  H. Lee Moffitt Cancer Center and Research Institute (1)  ·  Hunan Cancer Hospital (1)  ·  Jonsson Comprehensive Cancer Center (1)  ·  Meir Medical Center (1)  ·  Morphotek (1)  ·  Nasser Hanna, M.D. (1)  ·  Northwestern University (1)  ·  Pathway Genomics (1)

Countries

United States (23)  ·  China (3)  ·  Canada (2)  ·  Germany (2)  ·  Poland (2)  ·  Russia (2)  ·  Australia (1)  ·  Belarus (1)  ·  Hungary (1)  ·  Israel (1)  ·  Italy (1)  ·  Spain (1)  ·  Ukraine (1)

Top investigators

Alan Sandler (1)  ·  Ann Mauer (1)  ·  Binh Nguyen, MD, PhD (1)  ·  Charles Lu (1)  ·  Crystal Denlinger, MD (1)  ·  David Camidge (1)  ·  David Gandara (1)  ·  Edward Kim (1)  ·  Elisabeth Weiss, MD (1)  ·  Everett Vokes (1)  ·  Gary Strauss (1)  ·  Glennwood Goss (1)  ·  Jhanelle Gray, M.D. (1)  ·  Karen Kelly (1)  ·  Leora Horn (1)

Results publications

PMID 17167137, PMID 24100924, PMID 25870087, PMID 36816343, PMID 38206614, PMID 38261958

NIH funding

U10CA032102 (4), N01CM62201 (3), U10CA031946 (3), N01CM17102 (1), N01CM62207 (1), N01CM62208 (1), N01CM62209 (1), P30CA014599 (1), P30CA022453 (1), P50CA090949 (1), U10CA021115 (1), U10CA045809 (1), U10CA180888 (1)