8 completed, 4 active not recruiting, 3 recruiting, 3 withdrawn. 15 Phase 2, 8 Phase 1, 2 Not applicable, 1 Phase 3.
Follow Acute Lymphoblastic Leukemia in Remission: new trials by email Literature Review of Acute Lymphoblastic Leukemia in Remission trials Research Report on Acute Lymphoblastic Leukemia in Remission
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma Phentermine/Topiramate ER, Health Behavior and Lifestyle Counseling - Acute Lymphoblastic Leukemia in Remission, Hodgkin Lymphoma in Remission | Phase 2 | Not yet recruiting | St. Jude Children's Research Hospital | 100 | 2026-10-01 | 2026-09-23 |
| Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion CliniMACS - Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission | Not applicable | Active not recruiting | Baylor College of Medicine | 3 | 2023-12-06 | 2026-10-08 |
| MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing Magnetic-Activated Cell Sorter (CliniMACS, Miltenyi) - Leukemia, Acute Myeloid Leukemia in Remission | Not applicable | Recruiting | Medical College of Wisconsin | 40 | 2023-05-01 | 2026-05-13 |
| Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation Anti-Thymocyte Globulin, Busulfan, Cyclophosphamide - Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Phase 2 | Withdrawn | Fred Hutchinson Cancer Center | 2021-06-01 | 2021-06-30 | |
| Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia Allogeneic Stem Cell Transplantation - Acute Myeloid Leukemia in Remission, Acute Lymphoblastic Leukemia in Remission | Phase 2 | Active not recruiting | Universitätsklinikum Hamburg-Eppendorf | 167 | 2019-11-14 | 2025-04-22 |
| 211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome Astatine At 211 Anti-CD45 Monoclonal Antibody BC8-B10, Cyclophosphamide, Total-Body Irradiation - Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Phase 1 / Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 30 | 2019-07-10 | 2026-06-22 |
| Allogeneic Donor Lymphocyte Infusions Combined With Blinatumomab Blinatumomab in combination with donor lymphocyte infusion - B Cell Precursor Acute Lymphoblastic Leukemia With Mixed Chimerism or Minimal Residual Disease After Allogeneic Stem Cell Transplantation, B-Cell Acute Lymphoblastic Leukemia | Phase 2 | Withdrawn | Ludwig-Maximilians - University of Munich | 2019-06-01 | 2024-03-12 | |
| VPA Expanded UCB Transplantation for Treatment of Patients With Hematological Malignancies Cord blood stem cells, Valproic Acid, Fludarabine - Hematological Malignancy, Acute Leukemia in Remission | Phase 1 | Completed | Alla Keyzner | 7 | 2019-02-21 | 2021-05-24 |
| Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Reducing CMV Related Complications in Patients With Blood Cancer Undergoing Donor Stem Cell Transplant Multi-antigen CMV-Modified Vaccinia Ankara Vaccine, Laboratory Biomarker Analysis, Placebo - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia in Remission | Phase 2 | Withdrawn | City of Hope Medical Center | 2018-12-01 | 2018-11-21 | |
| CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant Multi-peptide CMV-Modified Vaccinia Ankara Vaccine - Accelerated Phase CML, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia in Remission | Phase 1 | Active not recruiting | City of Hope Medical Center | 34 | 2018-08-20 | 2026-09-28 |
| CD19 Chimeric Antigen Receptors and CD19 Positive Feeder T Cells as a Leukemia Consolidation Treatment CD19 CAR-T cells and CD19 positive feeder T cells - Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Unknown | Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd | 10 | 2018-08-02 | 2023-02-10 |
| Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome Fludarabine, Laboratory Biomarker Analysis, Melphalan - Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia in Remission | Phase 1 | Suspended | City of Hope Medical Center | 36 | 2018-07-06 | 2026-09-28 |
| Trial of AB-110 in Adults With Hematologic Malignancies Undergoing Cord Blood Transplantation Unmanipulated Umbilical Cord Blood (UCB), AB-110 - Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia in Remission | Phase 1 | Completed | Angiocrine Bioscience | 10 | 2018-04-24 | 2022-05-31 |
| Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia Cyclophosphamide, Cytarabine, Dexamethasone - Acute Lymphoblastic Leukemia in Remission, B Acute Lymphoblastic Leukemia | Phase 2 | Terminated | M.D. Anderson Cancer Center | 4 | 2018-03-28 | 2026-07-30 |
| Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma Anti-Thymocyte Globulin, Busulfan, Clofarabine - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Completed | M.D. Anderson Cancer Center | 6 | 2017-10-13 | 2023-10-11 |
| Personalized NK Cell Therapy in CBT Allogeneic Natural Killer Cell Line NK-92, Anti-Thymocyte Globulin, Busulfan - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 100 | 2016-05-19 | 2026-07-30 |
| Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant Laboratory Biomarker Analysis, Multi-peptide CMV-Modified Vaccinia Ankara Vaccine, Placebo - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia in Remission | Phase 2 | Active not recruiting | City of Hope Medical Center | 102 | 2015-12-21 | 2026-07-28 |
| Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Fludarabine Phosphate - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 84 | 2015-03-23 | 2026-06-01 |
| Fludarabine Phosphate, Clofarabine, and Busulfan With Vorinostat in Treating Patients With Acute Leukemia in Remission or Relapse Undergoing Donor Stem Cell Transplant Allogeneic Bone Marrow Transplantation, Allogeneic Hematopoietic Stem Cell Transplantation, Anti-Thymocyte Globulin - Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission | Phase 1 | Completed | M.D. Anderson Cancer Center | 70 | 2014-03-06 | 2022-01-06 |
| NK Cells in Cord Blood Transplantation Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Fludarabine Phosphate - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 1 | Unknown | M.D. Anderson Cancer Center | 13 | 2013-05-03 | 2020-02-11 |
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Myelodysplastic Syndromes (16) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (12) · Leukemia, Myeloid, Acute (11) · Hodgkin Disease (10) · Leukemia, Biphenotypic, Acute (9) · Leukemia, Myeloid, Chronic-Phase (9) · Lymphoma, Non-Hodgkin (9) · Leukemia, Myeloid, Accelerated Phase (8) · Leukemia, Lymphocytic, Chronic, B-Cell (6) · Anemia, Refractory, with Excess of Blasts (5) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (5) · Burkitt Lymphoma (4) · Hematologic Neoplasms (4) · Leukemia, Myelomonocytic, Chronic (4) · Primary Myelofibrosis (4)
Hemic and Lymphatic Diseases (22) · Neoplasms (22) · Neoplasms by Histologic Type (22) · Hematologic Diseases (21) · Immune System Diseases (21) · Immunoproliferative Disorders (21) · Lymphatic Diseases (21) · Lymphoproliferative Disorders (21) · Bone Marrow Diseases (20) · Leukemia (19) · Leukemia, Myeloid (18) · Leukemia, Lymphoid (17) · Pathologic Processes (16) · Pathological Conditions, Signs and Symptoms (16) · Chronic Disease (14)
Cyclophosphamide (10) · Whole-Body Irradiation (10) · fludarabine phosphate (10) · Mycophenolic Acid (8) · Peripheral Blood Stem Cell Transplantation (6) · Tacrolimus (6) · Cord Blood Stem Cell Transplantation (5) · Antilymphocyte Serum (4) · Busulfan (4) · CT-P10 (4) · Cyclosporine (4) · Melphalan (4) · Rituximab (4) · Clofarabine (3) · Cyclosporins (3)
Fred Hutchinson Cancer Center (6) · M.D. Anderson Cancer Center (5) · City of Hope Medical Center (4) · Alla Keyzner (1) · Angiocrine Bioscience (1) · Baylor College of Medicine (1) · Ludwig-Maximilians - University of Munich (1) · Medical College of Wisconsin (1) · Nohla Therapeutics, Inc. (1) · Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd (1) · St. Jude Children's Research Hospital (1) · Universitätsklinikum Hamburg-Eppendorf (1)
United States (21) · Germany (3) · Italy (2) · Austria (1) · China (1) · Czechia (1) · Finland (1) · Russia (1) · Spain (1)
Ryotaro Nakamura, MD (3) · Filippo Milano (2) · Alla Keyzner, MD (1) · Amanda Olson (1) · Brenda Sandmaier (1) · Chitra Hosing (1) · Christian Schmidt, MD (1) · Depei Wu, Ph.D (1) · Elias Jabbour (1) · Erin Morales, MD (1) · Marie Bleakley (1) · Marion Subklewe, MD (1) · Masumi Ueda Oshima (1) · Monzr Al Malki (1)
PMID 27760761, PMID 32040960, PMID 32499241, PMID 32706891, PMID 34049582, PMID 35007144, PMID 36594185
P30CA015704 (3), P30CA016672 (3), P01CA078902 (2), 2017 (1), P01CA018029 (1), P50HL110787 (1), R01CA077544 (1), R01CA211044 (1), R01HL121568 (1)