8 completed, 4 recruiting, 1 terminated. 9 Early Phase 1, 3 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 9 | Completed 5, Recruiting 3, Terminated 1 |
| Not applicable | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Non-Abstinence Outcomes in Methamphetamine Use Disorder Contingency Management - Methamphetamine Use Disorder | Not applicable | Recruiting | William Stoops | 300 | 2026-01-14 | 2026-06-08 |
| Cocaine and Pentoxifylline (BED IN 47) Placebo, Cocaine (IV), Pentoxifylline - Cocaine Use Disorder | Early Phase 1 | Recruiting | William Stoops | 30 | 2025-11-10 | 2026-06-08 |
| Methamphetamine and Troriluzole Placebo, Methamphetamine - Methamphetamine Use Disorder | Early Phase 1 | Recruiting | William Stoops | 40 | 2025-08-25 | 2026-06-08 |
| Suvorexant and Alcohol Alcohol, Placebo, Suvorexant - Alcohol Use Disorder | Early Phase 1 | Recruiting | William Stoops | 30 | 2024-06-07 | 2026-06-08 |
| Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine) n-acetylcysteine, Hydromorphone, Placebo n-acetylcystine - Cocaine Use Disorder, Opioid Use Disorder | Early Phase 1 | Completed | William Stoops | 12 | 2022-12-15 | 2026-05-05 |
| Cocaine and Zolmitriptan Cocaine, Placebo oral capsule, Zolmitriptan - Cocaine Use Disorder | Early Phase 1 | Completed | William Stoops | 12 | 2021-10-15 | 2025-08-05 |
| Suvorexant and Cocaine Suvorexant, Cocaine, Placebo oral capsule - Cocaine Use Disorder | Early Phase 1 | Completed | William Stoops | 8 | 2019-07-11 | 2023-02-09 |
| Behavioral Effects of Drugs (Inpatient): 38 Craving Manipulation, Cocaine, Placebo - Cocaine Use, Unspecified | Early Phase 1 | Terminated | William Stoops | 5 | 2019-05-15 | 2024-05-23 |
| Influence of n-Acetylcysteine Maintenance on Alcohol Effects Alcohol, Placebos, N-acetyl cysteine - Alcohol Use Disorder | Early Phase 1 | Completed | William Stoops | 14 | 2017-09-15 | 2021-01-26 |
| Cocaine Use Reduction and Health Contingency Management - Cocaine Use Disorder | Not applicable | Completed | William Stoops | 127 | 2017-09-15 | 2024-08-01 |
| Reinforcing Effects of Cocaine During Phendimetrazine Maintenance Phendimetrazine, Cocaine, Placebo - Cocaine Use Disorder | Phase 1 | Completed | William Stoops | 30 | 2015-08-01 | 2019-07-02 |
| Phendimetrazine and Cocaine Cocaine, Placebo - Cocaine Use Disorder | Early Phase 1 | Completed | William Stoops | 11 | 2014-09-01 | 2017-09-27 |
| Impact of Buspirone Maintenance on the Reinforcing Effects of Cocaine Buspirone, Placebo - Cocaine Use Disorders | Not applicable | Completed | William Stoops | 9 | 2012-09-01 | 2016-02-19 |
Alcoholism (2) · Opioid-Related Disorders (1)
Cocaine (6) · Acetylcysteine (2) · Ethanol (2) · suvorexant (2) · Buspirone (1) · Hydromorphone (1) · Methamphetamine (1) · Pentoxifylline (1) · phendimetrazine (1) · zolmitriptan (1)
United States (13)
William W Stoops, PhD (5) · William W Stoops, Ph.D. (3) · William W Stoops (1)
PMID 38006674, PMID 39504756, PMID 41343351
R01AA030775 (1), R01DA036553 (1), R01DA043938 (1), R01DA048617 (1), R01DA052203 (1), R01DA060632 (1), R01DA063069 (1), R01DA064144 (1), R21AA026129 (1), R33DA049130 (1)