2 completed, 1 active not recruiting, 1 no longer available. 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Active not recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Active not recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) TVI-Brain-1, Standard of Care, Radiotherapy - Glioblastoma Multiforme of Brain | Phase 2 / Phase 3 | Active not recruiting | TVAX Biomedical | 120 | 2023-12-27 | 2026-09-29 |
| Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma TVI-Brain-1 - Grade IV Glioma, Grade IV Astrocytoma | Phase 2 | Completed | TVAX Biomedical | 14 | 2011-06-01 | 2023-07-03 |
| Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma Cancer vaccine plus immune adjuvant - Glioma, High Grade Astrocytoma | Phase 1 / Phase 2 | Completed | TVAX Biomedical | 12 | 2010-04-01 | 2023-06-01 |
| TVI-Brain-1 in Expanded Access Patient TVI-Brain 1 - Recurrent Glioblastoma | No longer available | TVAX Biomedical | 2024-10-01 |
Glioblastoma (3) · Astrocytoma (2) · Brain Diseases (2) · Brain Neoplasms (2) · Central Nervous System Diseases (2) · Central Nervous System Neoplasms (2) · Glioma (2) · Neoplasms (2) · Nervous System Diseases (2) · Nervous System Neoplasms (2)
Adjuvants, Immunologic (3) · Cancer Vaccines (3) · Drug Therapy (1) · Radiotherapy (1) · Standard of Care (1) · Temozolomide (1)
United States (4)
Gary Wood, Ph.D. (1) · Gary Wood, PhD (1) · Michael Salacz, M.D. (1)