19 completed, 3 terminated, 1 active not recruiting, 1 not yet recruiting. 21 Not applicable, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 17, Active not recruiting 1, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 2 | 4 | Completed 2, Terminated 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Probiotics on Skin Health in Healthy Women Probiotics, Placebo - Skin Aging, Dry Skin | Not applicable | Not yet recruiting | Probi AB | 140 | 2026-10-01 | 2026-10-21 |
| Effects of Probiotics on the Gut-brain Axis in Children Probiotics, Placebo - Attention Deficit Hyperactivity Disorder (ADHD) | Not applicable | Recruiting | Probi AB | 80 | 2026-05-25 | 2026-07-07 |
| Effect of Probiotic Supplements on Osteoarthritis Outcomes Probiotic supplements, Placebo supplements - Knee Osteoarthritis | Not applicable | Active not recruiting | Lund University | 86 | 2024-07-01 | 2026-09-08 |
| Probiotic Intervention for Occasional Constipation Probiotics, Placebo - Gut Function, Occasional Constipation | Not applicable | Completed | Probi AB | 100 | 2024-06-25 | 2025-06-18 |
| Probiotic Intervention for Gut Function Probiotics, Placebo - Gut Function | Not applicable | Completed | Probi AB | 200 | 2023-02-08 | 2025-06-18 |
| Probiotic Intervention for Stress and Cognition Probiotics, Placebo - Stress, Cognition | Not applicable | Completed | Probi AB | 132 | 2021-07-07 | 2023-11-18 |
| Probiotic Intervention for Acute Stress Probiotic supplement, Placebo supplement - Stress | Not applicable | Completed | Probi AB | 70 | 2017-10-02 | 2019-03-20 |
| Efficacy of Probiotics on Physical Performance Probiotic supplement, Placebo - Physical Performance | Not applicable | Completed | Probi AB | 53 | 2017-08-14 | 2019-03-20 |
| Efficacy of Probiotics on Excessive Gas Accumulation Probiotic supplement, Placebo supplement - Flatulence, Bloating | Not applicable | Completed | Probi AB | 64 | 2017-04-18 | 2018-09-25 |
| Efficacy of Probiotics on Iron Status During Pregnancy Probiotics, Placebo - Prevention of Iron Deficiency | Not applicable | Completed | Probi AB | 326 | 2016-09-09 | 2020-03-04 |
| Efficacy of a Probiotic Product on Bone Mineral Density (BMD) in Healthy Women in Early Post-menopausal Phase Placebo, : Probiotic capsules - Osteopenia | Not applicable | Completed | Probi AB | 249 | 2016-04-01 | 2018-04-17 |
| Efficacy of a Probiotic Product in Children With Antibiotic-associated Gastrointestinal Disorders Probiotics, Placebo - Antibiotic-associated Diarrhea | Not applicable | Completed | Probi AB | 117 | 2016-02-03 | 2018-09-26 |
| The Efficacy of a Probiotic Product on Acute Upper Respiratory Tract Infections (Common Cold) in Healthy Children Probi Defendum, Placebo - Acute Upper Respiratory Tract Infections (Common Cold) | Not applicable | Completed | Probi AB | 550 | 2015-12-01 | 2018-10-17 |
| Probiotics in Radiation-treated Gynecologic Cancer Capsules placebo, Capsules probiotic powder and corn starch - Gastrointestinal Toxicity, Gynecologic Cancer | Not applicable | Terminated | Probi AB | 97 | 2015-02-01 | 2020-03-05 |
| Probiotics Against Low Grade Inflammation and Increased Intestinal Permeability in the Elderly Placebo, Active, only probiotics, Active, blend of berries and probiotics - Low-grade Inflammation, Increased Intestinal Permeability | Not applicable | Completed | Probi AB | 66 | 2015-01-01 | 2018-04-17 |
| Changes of Oropharyngeal Flora Probiotics, Placebo - Pharyngeal Bacterial Colonization, Pneumonia | Not applicable | Completed | Region Skane | 145 | 2014-10-01 | 2020-10-08 |
| The Effect of Probiotics on Symptoms and Intestinal Flora in Patients With Irritable Bowel Syndrome Probiotics, Control placebo - Irritable Bowel Syndrome | Phase 2 | Completed | Probi AB | 197 | 2014-05-02 | 2017-06-16 |
| Efficacy and Safety of a Probiotic Product in Children With Antibiotic-associated Gastrointestinal Disorders. Probiotic capsules, Placebo capsules - Antibiotic-associated Loose/Watery Stools | Phase 2 | Completed | Probi AB | 400 | 2013-10-01 | 2014-05-09 |
| Probiotics in Prevention of Common Cold Probiotic, Placebo - Viral Infections of the Upper Respiratory Tract | Not applicable | Completed | Probi AB | 899 | 2013-10-01 | 2018-04-17 |
| The Effect of a Probiotic on Protection Against Upper Respiratory Tract Infections in Children probiotic, placebo - Upper Respiratory Tract Infection | Phase 2 | Terminated | Probi AB | 131 | 2013-08-01 | 2015-12-03 |
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Attention Deficit Disorder with Hyperactivity (1) · Bone Diseases, Metabolic (1) · Common Cold (1) · Diarrhea (1) · Flatulence (1) · Irritable Bowel Syndrome (1) · Osteoarthritis, Knee (1) · Pneumonia (1) · Pneumonia, Ventilator-Associated (1) · Respiratory Tract Infections (1)
Probiotics (16) · Chlorhexidine (1) · Exercise (1) · Starch (1) · maltodextrin (1)
Sweden (13) · China (2) · Germany (2) · Poland (2) · Canada (1) · Ireland (1) · Italy (1) · Netherlands (1) · United Kingdom (1)
Bengt Klarin, MD, PhD (1) · Dan Curiac (1) · Eva Ageberg (1) · Michael Svensson, PhD (1) · Piotr Socha, Prof. (1) · Xiangjun Meng, MD (1)
PMID 18990201, PMID 28438377, PMID 29236734, PMID 30368249, PMID 33296464, PMID 33350604, PMID 38229392, PMID 38896223