Amgen: Clinical Trials

376 trials sponsored by Amgen, newest first

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276 completed, 34 terminated, 30 active not recruiting, 28 recruiting. 376 Phase 3, 14 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 3376Completed 276, Terminated 34, Active not recruiting 30, Recruiting 28, Withdrawn 4, Not yet recruiting 3, Unknown 1
Phase 214Completed 8, Terminated 4, Active not recruiting 1, Recruiting 1

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Trials (filtered) newest first · largest first

All 376 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Study Evaluating Subcutaneous Versus Intravenous Blinatumomab in Newly Diagnosed Adults With B-cell Precursor Acute Lymphoblastic Leukaemia
Blinatumomab, HyperCVAD - Philadelphia Chromosome Negative B-cell Precursor Acute Lymphoblastic Leukemia
Phase 3Not yet recruitingAmgen5602028-06-302026-09-15
Tarlatamab and Durvalumab vs. Durvalumab Alone for Limited-Stage-Small Cell Lung Cancer
Tarlatamab, Durvalumab - Limited Stage Small-Cell Lung Cancer
Phase 3Not yet recruitingPrECOG, LLC.4302027-01-012026-06-09
A Trial of Inebilizumab in Participants With Autoimmune Hepatitis
Inebilizumab, Placebo, Standard of Care - Autoimmune Hepatitis, AIH
Phase 3RecruitingAmgen1802026-12-182026-11-03
Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight
Maridebart cafraglutide, Autoinjector - Obesity, Overweight
Phase 3Not yet recruitingAmgen2302026-10-282026-10-13
Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes
Maridebart cafraglutide, Semaglutide - Diabetes Mellitus, Type 2
Phase 3RecruitingAmgen13002026-10-162026-11-05
A Phase 3 Study of Inebilizumab in Participants With Primary Membranous Nephropathy
Inebilizumab, Tacrolimus - Glomerulonephritis, Membranous
Phase 3RecruitingAmgen1592026-10-012026-10-01
Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC)
Tarlatamab - Small Cell Lung Cancer
Phase 3RecruitingAmgen4002026-08-282026-09-17
A Study of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of Previously Untreated Primary Immune Thrombocytopenia (ITP)
Romiplostim, Predniso(lo)ne - Primary Immune Thrombocytopenia
Phase 3RecruitingAmgen1262026-08-212026-09-17
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Maridebart Cafraglutide, Placebo - Obesity, Overweight
Phase 3RecruitingAmgen9502026-07-292026-10-05
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
Maridebart cafraglutide, Placebo - Obesity, Overweight
Phase 3RecruitingAmgen32002026-07-232026-10-05
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
ABP 938 8 mg, Aflibercept (US) 8 mg - Neovascular Age-related Macular Degeneration, nAMD
Phase 3RecruitingAmgen3042026-05-272026-10-14
TAVNEOS for Otolaryngologic Manifestations of Granulomatosis With Polyangiitis
Avacopan, Placebo - Granulomatosis With Polyangiitis, Wegener's
Phase 2 / Phase 3RecruitingRobert Spiera, MD302026-05-222026-09-02
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
Maridebart Cafraglutide - Obesity or Overweight
Phase 3RecruitingAmgen3002026-05-112026-11-06
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial
Olpasiran, Placebo - Cardiovascular Disease
Phase 3RecruitingAmgen4062026-03-232026-04-16
Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta
Vitamin D, Calcium - Osteogenesis Imperfecta
Phase 3RecruitingAmgen712026-03-182026-06-22
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
Pegloticase, Methotrexate - Uncontrolled Gout
Phase 3RecruitingAmgen2702026-02-092026-10-19
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy
Maridebart cafraglutide, Placebo - Obesity, Obstructive Sleep Apnea
Phase 3Active not recruitingAmgen2502025-12-192026-10-06
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Xaluritamig, Abiraterone acetate, Docetaxel - Metastatic Castration-resistant Prostate Cancer
Phase 3RecruitingAmgen7502025-11-282026-10-20
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy
Maridebart cafraglutide, Placebo - Obstructive Sleep Apnea
Phase 3Active not recruitingAmgen2502025-11-252026-09-29
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Olpasiran, Placebo - Cardiovascular Disease
Phase 3RecruitingAmgen110002025-08-222026-08-21

Showing 20 of 376. Sign in to see all of them.

Conditions studied

Anemia (29)  ·  Renal Insufficiency, Chronic (29)  ·  Neoplasms (28)  ·  Psoriasis (27)  ·  Hypercholesterolemia (24)  ·  Breast Neoplasms (18)  ·  Arthritis, Rheumatoid (17)  ·  Osteoporosis (17)  ·  Hyperparathyroidism, Secondary (16)  ·  Multiple Myeloma (15)  ·  Bone Diseases, Metabolic (14)  ·  Osteoporosis, Postmenopausal (14)  ·  Kidney Diseases (13)  ·  Arthritis (12)  ·  Colorectal Neoplasms (12)

Interventions

Darbepoetin alfa (35)  ·  Denosumab (35)  ·  evolocumab (32)  ·  Etanercept (25)  ·  apremilast (24)  ·  Cinacalcet (13)  ·  romiplostim (13)  ·  tezepelumab (12)  ·  Cyclophosphamide (11)  ·  Panitumumab (11)  ·  Dexamethasone (10)  ·  carfilzomib (10)  ·  etelcalcetide hydrochloride (9)  ·  Docetaxel (8)  ·  Methotrexate (8)

Countries

United States (212)  ·  Canada (150)  ·  Germany (135)  ·  Spain (130)  ·  France (127)  ·  Poland (125)  ·  Italy (119)  ·  Belgium (114)  ·  United Kingdom (109)  ·  Australia (108)  ·  Hungary (99)  ·  Czechia (98)  ·  Japan (81)  ·  Netherlands (74)  ·  South Korea (74)

Top investigators

Corinne Haioun, MD (3)  ·  Andrew Menzies-Gow, MD (2)  ·  A Bacigalupo, Dr. (1)  ·  A Bosi, Dr. (1)  ·  A Ferrant, Dr (1)  ·  A Gratwohl, Dr. (1)  ·  A Nagler, Dr. (1)  ·  A Zander, Dr (1)  ·  A. Pagliuca, Dr. (1)  ·  Afsaneh Barzi, MD (1)  ·  Alfredo Carrato, MD, PhD (1)

Results publications

PMID 37316690, PMID 33078867, PMID 36791280, PMID 38979716, PMID 42825996, PMID 19671919, PMID 22975218, PMID 23975226, PMID 24144944, PMID 26049686, PMID 26093811, PMID 26373676, PMID 29627309, PMID 30018799, PMID 31077258, PMID 31776637, PMID 31909868, PMID 34536218, PMID 36702146, PMID 37185961, PMID 16710026, PMID 18227526, PMID 18242413, PMID 20533525, PMID 20957659, PMID 22070868, PMID 22152181, PMID 22494019, PMID 22508812, PMID 24014831, PMID 25976743, PMID 26165391, PMID 26335402, PMID 26771810, PMID 27282998, PMID 30679026, PMID 31378656, PMID 33263165, PMID 34037241, PMID 34252375, PMID 34928306, PMID 35978286, PMID 38308771, PMID 38573517, PMID 39326921, PMID 40341124, PMID 11277825, PMID 12115173, PMID 15229957, PMID 15248226

NIH funding

2023 (18), 2014 (13), 2009 (9), 2017 (9), 2015 (7), 2025 (6), 2016 (5), 2018 (4), 2005 (3), 2019 (3), 1UF1AG046150-01 (1), 2008 (1), P30CA014089 (1)