276 completed, 34 terminated, 30 active not recruiting, 28 recruiting. 376 Phase 3, 14 Phase 2.
By phase and status
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Trials (filtered) newest first · largest first
All 376 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
A Study Evaluating Subcutaneous Versus Intravenous Blinatumomab in Newly Diagnosed Adults With B-cell Precursor Acute Lymphoblastic Leukaemia Blinatumomab, HyperCVAD - Philadelphia Chromosome Negative B-cell Precursor Acute Lymphoblastic Leukemia | Phase 3 | Not yet recruiting | 560 | 2028-06-30 | 2026-09-15 |
Tarlatamab and Durvalumab vs. Durvalumab Alone for Limited-Stage-Small Cell Lung Cancer Tarlatamab, Durvalumab - Limited Stage Small-Cell Lung Cancer | Phase 3 | Not yet recruiting | 430 | 2027-01-01 | 2026-06-09 |
A Trial of Inebilizumab in Participants With Autoimmune Hepatitis Inebilizumab, Placebo, Standard of Care - Autoimmune Hepatitis, AIH | Phase 3 | Recruiting | 180 | 2026-12-18 | 2026-11-03 |
Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight Maridebart cafraglutide, Autoinjector - Obesity, Overweight | Phase 3 | Not yet recruiting | 230 | 2026-10-28 | 2026-10-13 |
Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes Maridebart cafraglutide, Semaglutide - Diabetes Mellitus, Type 2 | Phase 3 | Recruiting | 1300 | 2026-10-16 | 2026-11-05 |
A Phase 3 Study of Inebilizumab in Participants With Primary Membranous Nephropathy Inebilizumab, Tacrolimus - Glomerulonephritis, Membranous | Phase 3 | Recruiting | 159 | 2026-10-01 | 2026-10-01 |
Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC) Tarlatamab - Small Cell Lung Cancer | Phase 3 | Recruiting | 400 | 2026-08-28 | 2026-09-17 |
A Study of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of Previously Untreated Primary Immune Thrombocytopenia (ITP) Romiplostim, Predniso(lo)ne - Primary Immune Thrombocytopenia | Phase 3 | Recruiting | 126 | 2026-08-21 | 2026-09-17 |
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION) Maridebart Cafraglutide, Placebo - Obesity, Overweight | Phase 3 | Recruiting | 950 | 2026-07-29 | 2026-10-05 |
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION) Maridebart cafraglutide, Placebo - Obesity, Overweight | Phase 3 | Recruiting | 3200 | 2026-07-23 | 2026-10-05 |
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration ABP 938 8 mg, Aflibercept (US) 8 mg - Neovascular Age-related Macular Degeneration, nAMD | Phase 3 | Recruiting | 304 | 2026-05-27 | 2026-10-14 |
TAVNEOS for Otolaryngologic Manifestations of Granulomatosis With Polyangiitis Avacopan, Placebo - Granulomatosis With Polyangiitis, Wegener's | Phase 2 / Phase 3 | Recruiting | 30 | 2026-05-22 | 2026-09-02 |
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH) Maridebart Cafraglutide - Obesity or Overweight | Phase 3 | Recruiting | 300 | 2026-05-11 | 2026-11-06 |
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial Olpasiran, Placebo - Cardiovascular Disease | Phase 3 | Recruiting | 406 | 2026-03-23 | 2026-04-16 |
Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta Vitamin D, Calcium - Osteogenesis Imperfecta | Phase 3 | Recruiting | 71 | 2026-03-18 | 2026-06-22 |
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout Pegloticase, Methotrexate - Uncontrolled Gout | Phase 3 | Recruiting | 270 | 2026-02-09 | 2026-10-19 |
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy Maridebart cafraglutide, Placebo - Obesity, Obstructive Sleep Apnea | Phase 3 | Active not recruiting | 250 | 2025-12-19 | 2026-10-06 |
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer Xaluritamig, Abiraterone acetate, Docetaxel - Metastatic Castration-resistant Prostate Cancer | Phase 3 | Recruiting | 750 | 2025-11-28 | 2026-10-20 |
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy Maridebart cafraglutide, Placebo - Obstructive Sleep Apnea | Phase 3 | Active not recruiting | 250 | 2025-11-25 | 2026-09-29 |
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events Olpasiran, Placebo - Cardiovascular Disease | Phase 3 | Recruiting | 11000 | 2025-08-22 | 2026-08-21 |
Showing 20 of 376. Sign in to see all of them.
Conditions studied
Anemia (29) · Renal Insufficiency, Chronic (29) · Neoplasms (28) · Psoriasis (27) · Hypercholesterolemia (24) · Breast Neoplasms (18) · Arthritis, Rheumatoid (17) · Osteoporosis (17) · Hyperparathyroidism, Secondary (16) · Multiple Myeloma (15) · Bone Diseases, Metabolic (14) · Osteoporosis, Postmenopausal (14) · Kidney Diseases (13) · Arthritis (12) · Colorectal Neoplasms (12)
Interventions
Darbepoetin alfa (35) · Denosumab (35) · evolocumab (32) · Etanercept (25) · apremilast (24) · Cinacalcet (13) · romiplostim (13) · tezepelumab (12) · Cyclophosphamide (11) · Panitumumab (11) · Dexamethasone (10) · carfilzomib (10) · etelcalcetide hydrochloride (9) · Docetaxel (8) · Methotrexate (8)
Countries
United States (212) · Canada (150) · Germany (135) · Spain (130) · France (127) · Poland (125) · Italy (119) · Belgium (114) · United Kingdom (109) · Australia (108) · Hungary (99) · Czechia (98) · Japan (81) · Netherlands (74) · South Korea (74)
Top investigators
Corinne Haioun, MD (3) · Andrew Menzies-Gow, MD (2) · A Bacigalupo, Dr. (1) · A Bosi, Dr. (1) · A Ferrant, Dr (1) · A Gratwohl, Dr. (1) · A Nagler, Dr. (1) · A Zander, Dr (1) · A. Pagliuca, Dr. (1) · Afsaneh Barzi, MD (1) · Alfredo Carrato, MD, PhD (1)
Results publications
PMID 37316690, PMID 33078867, PMID 36791280, PMID 38979716, PMID 42825996, PMID 19671919, PMID 22975218, PMID 23975226, PMID 24144944, PMID 26049686, PMID 26093811, PMID 26373676, PMID 29627309, PMID 30018799, PMID 31077258, PMID 31776637, PMID 31909868, PMID 34536218, PMID 36702146, PMID 37185961, PMID 16710026, PMID 18227526, PMID 18242413, PMID 20533525, PMID 20957659, PMID 22070868, PMID 22152181, PMID 22494019, PMID 22508812, PMID 24014831, PMID 25976743, PMID 26165391, PMID 26335402, PMID 26771810, PMID 27282998, PMID 30679026, PMID 31378656, PMID 33263165, PMID 34037241, PMID 34252375, PMID 34928306, PMID 35978286, PMID 38308771, PMID 38573517, PMID 39326921, PMID 40341124, PMID 11277825, PMID 12115173, PMID 15229957, PMID 15248226
NIH funding
2023 (18), 2014 (13), 2009 (9), 2017 (9), 2015 (7), 2025 (6), 2016 (5), 2018 (4), 2005 (3), 2019 (3), 1UF1AG046150-01 (1), 2008 (1), P30CA014089 (1)