51 completed, 9 unknown, 7 recruiting, 4 active not recruiting. 51 Not applicable, 6 Phase 4, 5 Phase 2, 4 Phase 3, 2 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OBESIAL: A Prospective Interventional Real-world Study of a Multidisciplinary Obesity Management Programme Semaglutide (Wegovy) weekly injection, Behavioral Treatment, Weight loss - Obesity Difficult Airway Airway Management, Obesity Adult Onset | Not applicable | Recruiting | University of Health Sciences, Algeria | 300 | 2026-01-22 | 2026-08-21 |
| Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term Acetazolamide Acetazolamide, Stent (Tentos 4F or Precise ProRX) - Idiopathic Intracranial Hypertension (IIH) | Not applicable | Recruiting | University Hospital, Montpellier | 114 | 2026-01-05 | 2026-03-06 |
| Intracranial Venous Stenting Evaluation in Patients With Idiopathic Intracranial Hypertension in the Early Phase Best medical care, Intervention (stenting) - Idiopathic Intracranial Hypertension (IIH) | Not applicable | Recruiting | University Hospital, Montpellier | 114 | 2025-09-19 | 2025-10-03 |
| Impact of Weight Loss on Mitochondrial Function Weight loss - Weight Loss, Bariatric Surgery | Not yet recruiting | Towson University | 15 | 2025-07-28 | 2025-06-15 | |
| Acute and Chronic Effects of Obesity Weight loss - Obesity & Overweight, Metabolism Changes | Recruiting | Concordia University, Montreal | 150 | 2025-04-30 | 2026-04-07 | |
| Tailored Exercise Training Study Among Adults With HFpEF Moderate-intensity continuous training (MCT), Resistance training, Weight loss - HFpEF - Heart Failure With Preserved Ejection Fraction, Diabetic Cardiomyopathies | Phase 2 / Phase 3 | Recruiting | University of Texas Southwestern Medical Center | 120 | 2025-02-18 | 2025-10-31 |
| 4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity Weight Loss - Breast Cancer | Not applicable | Active not recruiting | University of Colorado, Denver | 36 | 2024-05-28 | 2026-09-01 |
| Weight Change and the Risk of Chronic Pain Following Hip and Knee Arthroplasties Weight gain, Weight loss, Weight unchanged - Persistent Postsurgical Pain, Arthritis Knee | Unknown | Bispebjerg Hospital | 6400 | 2023-11-01 | 2023-09-06 | |
| A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program Weight loss - Obesity | Not applicable | Recruiting | University of Pittsburgh | 205 | 2023-09-29 | 2026-06-12 |
| Choosing Healthy Activities and Lifestyle Management Through Portal Support Active Intervention Group, Comparison Group - Weight Loss, Overweight and Obesity | Not applicable | Active not recruiting | University of Tennessee | 229 | 2023-02-24 | 2025-11-20 |
| Stent Implantation Versus Medical Therapy for Idiopathic IntracraniaL Hypertension (SIMPLE) Stent Implantation, Acetazolamide-based medical therapy, Weight loss - Idiopathic Intracranial Hypotension, Venous Sinus Stenosis | Phase 3 | Recruiting | Beijing Tiantan Hospital | 74 | 2023-02-16 | 2026-02-10 |
| Impact of Weight Loss in Cirrhosis With Obesity and MAFLD Weight loss - Liver Cirrhosis, Obesity | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 96 | 2021-11-10 | 2023-03-01 |
| Effects of a Weight Loss Program in People With Hip Osteoarthritis Weight loss, Exercise - Hip Osteoarthritis, Overweight and Obesity | Not applicable | Completed | University of Melbourne | 101 | 2021-06-16 | 2024-04-05 |
| Dairy Protien Rich Diet for NAFLD Patients High-Protein Diet, Clinical dietician, Weight loss - Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome | Not applicable | Completed | University of Aarhus | 46 | 2021-03-15 | 2025-04-01 |
| Reducing Obesity and Cartilage Compression in Knees Weight Loss - Obesity, Osteoarthritis | Not applicable | Completed | Duke University | 88 | 2020-06-05 | 2024-06-06 |
| Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss Weight loss, Exercise - Peripheral Artery Disease, Overweight or Obesity | Not applicable | Active not recruiting | Northwestern University | 212 | 2020-03-01 | 2026-09-24 |
| Effects of Weight Loss on Vascular Function in Obese Subjects Weight Loss - Obesity | Not applicable | Unknown | Mario Fritsch Neves | 50 | 2019-11-21 | 2019-12-17 |
| Pathogenesis of Uric Acid Nephrolithiasis: Role of Pioglitazone/Weight Loss Pioglitazone 45 mg, Weight Loss, Pioglitazone + Weight Loss - Nephrolithiasis, Uric Acid | Phase 4 | Completed | University of Texas Southwestern Medical Center | 29 | 2019-10-17 | 2026-08-31 |
| Adaptive Responses to Overfeeding and Weight Weight Loss, Exercise training, Overfeeding - Obesity | Not applicable | Unknown | University of Colorado, Denver | 75 | 2019-02-15 | 2023-04-07 |
| Weight Loss on IVF Outcomes in Overweight and Obese Infertile Women weight loss - Infertility, Weight Loss | Not applicable | Completed | Peking University People's Hospital | 197 | 2019-01-01 | 2025-09-16 |
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Obesity (47) · Weight Loss (39) · Overweight (14) · Metabolic Syndrome (10) · Insulin Resistance (9) · Motor Activity (9) · Cardiovascular Diseases (4) · Hypertension (4) · Non-alcoholic Fatty Liver Disease (4) · Arthritis (3) · Pseudotumor Cerebri (3) · Weight Gain (3) · Breast Neoplasms (2) · Diabetes Mellitus (2) · Diabetes Mellitus, Type 2 (2)
VA Office of Research and Development (5) · Washington University School of Medicine (4) · Duke University (3) · University of Colorado, Denver (3) · Baylor College of Medicine (2) · National Heart, Lung, and Blood Institute (NHLBI) (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Rutgers University (2) · Stanford University (2) · US Department of Veterans Affairs (2) · University Hospital, Montpellier (2) · University of Aarhus (2) · University of Missouri-Columbia (2) · University of Pittsburgh (2) · University of Texas Southwestern Medical Center (2)
United States (49) · Canada (4) · Denmark (3) · France (3) · China (2) · Algeria (1) · Australia (1) · Brazil (1) · India (1) · Israel (1) · Norway (1) · United Kingdom (1)
Samuel Klein, MD (2) · Adelaide Hebert, MD (1) · Alice S Ryan, PhD (1) · Angelo Tremblay, Ph.D (1) · Barbara Nicklas, PhD (1) · Bettina Mittendorfer, PhD (1) · Bret H Goodpaster, PhD (1) · Cheryl Lovelady, PhD (1) · Cheryl Rock, PhD, RD (1) · Christos Coutifaris, M.D., Ph.D. (1) · Connie Bales, PhD, RD (1) · Connie Bales, RD, PhD (1) · Daniel Bessesen, MD (1) · Dapeng Mo, MD (1) · David Bradley, MD (1)
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R01AG012161 (2), IK2RX001788-01 (1), K23HD049454 (1), R01AG025501 (1), R01AG051624 (1), R01CA258766 (1), R01CA267643 (1), R01HD093047 (1), R01HL076441 (1), R03DK118215 (1), R29HL056127 (1), U24DK128125 (1), U54CA155435 (1), UG3HL141729-01A1 (1), UH3DK128298 (1)