11 completed, 4 terminated, 3 unknown, 1 withdrawn. 19 Phase 2, 8 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 19 | Completed 11, Terminated 4, Unknown 3, Withdrawn 1 |
| Phase 3 | 8 | Completed 6, Unknown 2 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
Follow Vitamin B 6: new trials by email Literature Review of Vitamin B 6 trials Research Report on Vitamin B 6
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Efficacy of B6 and Metoclopramide Combination in Comparison With the Other Antiemetics Metoclopramide and Vitamin B6, Vitamin B6, Ondansetron - Vomiting | Phase 2 / Phase 3 | Completed | University of Baghdad | 250 | 2024-01-30 | 2024-04-30 |
| Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals Dolutegravir (DTG), Isoniazid (INH), Rifapentine (RPT) - HIV Infection, LTBI | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 37 | 2021-02-27 | 2024-09-19 |
| StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosis Pravastatin, Rifafour, Vitamin B6 - Tuberculosis, Pulmonary Tuberculosis | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 16 | 2020-02-21 | 2023-09-18 |
| Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics Pyridoxine, Cobalamin, Placebo Oral Tablet - Schizophrenia, Drug Induced Movement Disorder, Unspecified | Phase 2 / Phase 3 | Unknown | Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara | 45 | 2019-09-03 | 2019-12-18 |
| Vitamin B6 and Magnesium- A Clinical Trial on ASD Patients Magnesium and Vitamin B6 - Autism Spectrum Disorder | Phase 2 | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 50 | 2019-01-01 | 2019-07-31 |
| Evaluate the Neuroprotective Effect of Vitamin B6 and Vitamin B12 Against Vincristine Induced Neurotoxicity in Acute Lymphoblastic Leukaemia Patients Injection Mecobalamin, Tablet Pyridoxine hydrochlorid, Normal saline - Vincristine Induced Neurotoxicity, Acute Lymphoblastic Leukaemia | Phase 2 / Phase 3 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 40 | 2018-03-29 | 2020-07-08 |
| Nutraceuticals Versus Usual Care in the Prevention or Reduction of CIPN in Patients Treated With Docetaxel as Neoadjuvant/Adjuvant Breast Cancer Therapy Vitamin D, Vitamin B6, Vitamin B12 - Peripheral Neuropathy in Breast Cancer Patient | Phase 2 | Terminated | AHS Cancer Control Alberta | 13 | 2017-06-27 | 2019-07-05 |
| Evaluating PK, Tolerability, and Safety of Rifapentine and Isoniazid in Pregnant and Postpartum Women Rifapentine (RPT), Isoniazid (INH), Pyridoxine (vitamin B6) - Tuberculosis | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 50 | 2017-03-13 | 2021-11-04 |
| Treatment of Nodding Syndrome - A Randomized Blinded Placebo-Controlled Crossover Trial of Oral Pyridoxine and Conventional Anti-Epileptic Therapy, in Northern Uganda - 2012 Pyridoxine, Sodium Valproate, Phenytoin - Nodding Syndrome | Phase 2 | Withdrawn | Centers for Disease Control and Prevention | 2016-02-01 | 2022-05-18 | |
| High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB) Isoniazid, Vitamin B6 - Tuberculosis | Phase 2 | Completed | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 282 | 2014-08-13 | 2023-02-17 |
| The Effects of Vitamin B-6 and Coenzyme Q10 Status on Oxidative Stress, Antioxidant Capacities, and Inflammatory Responses in Patients With Liver Cancer Vitamin B-6, Coenzyme Q10, Vitamin B-6+Coenzyme Q10 - Hepatocellular Carcinoma. | Phase 2 / Phase 3 | Completed | Taichung Veterans General Hospital | 71 | 2014-01-01 | 2016-06-15 |
| Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV Standard-dose Lopinavir/Ritonavir, Double-dose Lopinavir/Ritonavir, Raltegravir - HIV Infection, Tuberculosis | Phase 2 | Terminated | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 71 | 2013-07-13 | 2018-02-13 |
| The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer Vitamin C, Vitamin B6, Folic acid - Colorectal Cancer | Phase 2 / Phase 3 | Unknown | Taichung Veterans General Hospital | 300 | 2011-08-01 | 2014-02-19 |
| Sunitinib or Cediranib for Alveolar Soft Part Sarcoma Cediranib, Sunitinib, Prochlorperazine - Sarcoma, Alveolar Soft Part | Phase 2 | Completed | National Cancer Institute (NCI) | 34 | 2011-07-18 | 2026-02-02 |
| Trial on Treatment of Patients With Primary Hyperoxaluria Type I With Pyridoxal-phosphate Vitamin B 6 - Primary Hyperoxaluria Type I | Phase 2 | Completed | University of Cologne | 12 | 2010-12-01 | 2012-10-29 |
| Vitamin B6 Effects for Women Taking Birth Control Pills Vitamin B6, Infusion of labeled serine, methionine and leucine - Vitamin B6 Deficiency | Phase 2 / Phase 3 | Completed | University of Florida | 13 | 2010-04-01 | 2017-02-07 |
| Addition of Modulators of Homocysteine to Adalimumab Therapy in the Treatment of Moderate to Severe Plaque Psoriasis Humira Then Humira plus 3 B vitamins - Psoriasis | Phase 1 / Phase 2 | Terminated | Wayne State University | 8 | 2009-01-01 | 2015-02-04 |
| Combination Natural Health Product in Children With Attention Deficit/Hyperactivity Disorder (ADHD) Zinc, Magnesium, Vitamin B6, Vitamin C (Compound Natural Health Product for ADHD) - Attention Deficit Hyperactivity Disorder | Phase 2 / Phase 3 | Completed | Kieran Cooley | 28 | 2008-09-01 | 2015-10-19 |
| BVAIT: B-Vitamin Atherosclerosis Intervention Trial folic acid, vitamin B12, vitamin B6 - Atherosclerosis | Phase 2 / Phase 3 | Completed | National Institute on Aging (NIA) | 506 | 2000-11-01 | 2009-12-11 |
Tuberculosis (4) · HIV Infections (2) · Atherosclerosis (1) · Attention Deficit Disorder with Hyperactivity (1) · Autism Spectrum Disorder (1) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1) · Cardiovascular Diseases (1) · Colorectal Neoplasms (1) · Hyperoxaluria (1) · Hyperoxaluria, Primary (1) · Impulsive Behavior (1) · Nodding Syndrome (1) · Peripheral Nervous System Diseases (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
National Institute of Allergy and Infectious Diseases (NIAID) (3) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (2) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (2) · Taichung Veterans General Hospital (2) · AHS Cancer Control Alberta (1) · Centers for Disease Control and Prevention (1) · Kieran Cooley (1) · National Cancer Institute (NCI) (1) · National Institute on Aging (NIA) (1) · Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara (1) · University of Baghdad (1) · University of Cologne (1) · University of Florida (1) · Wayne State University (1)
Haiti (4) · South Africa (4) · United States (4) · Bangladesh (2) · Brazil (2) · Canada (2) · Kenya (2) · Malawi (2) · Taiwan (2) · Thailand (2) · Zimbabwe (2) · Botswana (1) · Germany (1) · Iraq (1) · Peru (1)
Alice P Chen, M.D. (1) · Andreas H Diacon, MD, PhD (1) · Anthony Podany, PharmD (1) · Constance A Benson, MD (1) · Hashim Talib T Hashim, MBChB (1) · Heather Boon, PhD (1) · Howard N. Hodis, MD (1) · Jesse Gregory, PhD (1) · Jyoti S. Mathad, MD, MSc (1) · Katia Tonkin, MD (1) · Kelly Dooley, MD, PhD (1) · Lia LO Sanders, MD, PhD (1) · Neil Martinson, MD, MPH (1) · Peter J Aronson, MD (1)
PMID 19118243, PMID 24385516, PMID 25527663, PMID 26201817, PMID 26765812, PMID 27051670, PMID 27716246, PMID 31945300, PMID 34323955, PMID 34403326, PMID 35526057, PMID 36302173, PMID 38564365, PMID 38568956
R01AG017160 (1), U01AI068636 (1), UM1AI068636 (1)