6 unknown, 5 completed, 1 not yet recruiting, 1 recruiting. 13 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Unknown 6, Completed 5, Not yet recruiting 1, Recruiting 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
Follow Trimetazidine: new trials by email Literature Review of Trimetazidine trials Research Report on Trimetazidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Trimetazidine on Coronary Flow in Transthyretin Cardiac Amyloidosis Trimetazidine - Transthyretin Cardiac Amyloidosis | Phase 2 | Not yet recruiting | Fábio Fernandes | 20 | 2027-01-01 | 2026-10-23 |
| Effect of Trimetazidine on Endothelin-1 and Clinical Outcomes of Patients With Diabetic Peripheral Neuropathy Trimetazidine Dihydrochloride Tablets - Diabetic Peripheral Neuropathic Pain (DPN) | Phase 1 / Phase 2 | Recruiting | Sara Refaat Azab Metry | 60 | 2026-08-01 | 2026-08-31 |
| Trimetazidine Efficacy in Attenuating Paclitaxel-Induced Peripheral Neuropathy Trimetazidine, Placebo - Peripheral Neuropathy Due to Chemotherapy | Phase 1 / Phase 2 | Completed | Minia University | 60 | 2024-06-23 | 2025-03-30 |
| Benefits of Trimetazidine in MASLD Patients Trimetazidine, Conventional therapy, Placebo - Metabolic Associated Fatty Liver Disease | Phase 2 | Completed | October 6 University | 60 | 2023-12-10 | 2025-07-11 |
| Efficacy of Trimetazidine in Diabetic Patients Trimetazidine Dihydrochloride, Placebo - Diabetes Mellitus, Type 2, Diabetic Cardiomyopathies | Phase 2 | Unknown | Ain Shams University | 60 | 2022-09-18 | 2022-09-27 |
| The Effects of TMZ on Diabetic Nephropathy Trimetazidine - Diabetic Nephropathies | Phase 2 | Unknown | Tongji Hospital | 150 | 2022-01-01 | 2021-12-07 |
| Targeting Metabolic Flexibility in Amyotrophic Lateral Sclerosis (ALS) Trimetazidine Dihydrochloride - Amyotrophic Lateral Sclerosis, Motor Neuron Disease | Phase 2 | Completed | The University of Queensland | 21 | 2021-06-29 | 2023-07-20 |
| Effect of Trimetazidine on Radiotherapy-induced Heart Damage. Trimetazidine - Cardiotoxicity | Phase 2 / Phase 3 | Unknown | Peking University Third Hospital | 80 | 2021-06-25 | 2021-06-25 |
| Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19 Trimetazidine - Acute Respiratory Distress Syndrome, Covid19 | Phase 2 | Unknown | Ministry of Health, Brazil | 80 | 2020-12-10 | 2021-02-21 |
| Trimetazidine as an Adjunct to Enhance Clopidogrel Response. Trimetazidine - Platelet Dysfunction Due to Drugs | Phase 2 | Completed | The University of The West Indies | 24 | 2018-07-01 | 2019-12-02 |
| The Role of Trimetazidine on Right Ventricle Function in Pulmonary Arterial Hypertension Trimetazidine, Placebo oral capsule - Precapillary Pulmonary Hypertension | Phase 2 / Phase 3 | Completed | Universitas Indonesia | 26 | 2017-09-10 | 2019-10-03 |
| Trimetazidine in Pulmonary Artery Hypertension Trimetazidine - Pulmonary Artery Hypertension | Phase 2 | Unknown | Pontificia Universidad Catolica de Chile | 25 | 2014-03-01 | 2014-04-03 |
| Trimetazidine Therapy in Hypertrophic Cardiomyopathy Trimetazidine, Placebo capsule - Hypertrophic Cardiomyopathy | Phase 2 | Unknown | University College, London | 90 | 2012-04-01 | 2013-02-28 |
Amyotrophic Lateral Sclerosis (1) · COVID-19 (1) · Cardiomyopathy, Hypertrophic (1) · Cardiotoxicity (1) · Coronavirus Infections (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Cardiomyopathies (1) · Diabetic Nephropathies (1) · Familial Primary Pulmonary Hypertension (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Motor Neuron Disease (1) · Peripheral Nervous System Diseases (1) · Respiratory Distress Syndrome (1)
Ain Shams University (1) · Fábio Fernandes (1) · Minia University (1) · Ministry of Health, Brazil (1) · October 6 University (1) · Peking University Third Hospital (1) · Pontificia Universidad Catolica de Chile (1) · Sara Refaat Azab Metry (1) · The University of Queensland (1) · The University of The West Indies (1) · Tongji Hospital (1) · Universitas Indonesia (1) · University College, London (1)
Egypt (4) · Brazil (2) · United Kingdom (2) · Australia (1) · Chile (1) · Indonesia (1) · Netherlands (1) · Trinidad and Tobago (1)
Ahmed Mostafa Abd-Elaziz, Lecturer (1) · Ammar Al-Chalabi, MB ChB, PhD (1) · Asmaa N. Iqbal Ahmed, Demonstrator (1) · Dan Zhu, doctor (1) · Eman M. Sadek, Lecturer (1) · Engy A. Wahsh, Asst. Prof. (1) · Fatma M. Mady, Professor (1) · Felipe Gallego Lima, MD (1) · Frederik Steyn, PhD (1) · Hary Sakti Muliawan, MD,PhD (1) · Lamia El Wakeel, PhD (1) · Leonard van den Berg, MD, PhD (1) · Luis Henrique Wolff Gowdak, MD, PhD (1) · Noha Mahmood Abd-Allah, Lecturer (1)