3 completed, 2 withdrawn, 1 terminated, 1 unknown. 3 Phase 1, 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Terminated 1, Withdrawn 1 |
| Phase 3 | 2 | Completed 2 |
Follow ThermoDox: new trials by email Literature Review of ThermoDox trials Research Report on ThermoDox
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors Magnetic Resonance-Guided High Intensity Focused Ultrasound, Lyso-thermosensitive Liposomal Doxorubicin - Solid Tumors, Soft Tissue Sarcoma | Phase 2 | Withdrawn | Children's National Research Institute | 2022-11-10 | 2025-01-01 | |
| PanDox: Targeted Doxorubicin in Pancreatic Tumours Focused Ultrasound, Doxorubicin, ThermoDox - Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer Stage IV | Phase 1 | Withdrawn | University of Oxford | 2021-06-16 | 2023-04-12 | |
| Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer LTLD, MR-HIFU induced hyperthermia, Cyclophosphamide - Metastatic Breast Cancer, Breast Cancer | Phase 1 | Unknown | UMC Utrecht | 12 | 2021-03-01 | 2021-02-17 |
| Study of ThermoDox With Standardized Radiofrequency Ablation (RFA) for Treatment of Hepatocellular Carcinoma (HCC) ThermoDox, Dummy infusion - Hepatocellular Carcinoma | Phase 3 | Completed | Imunon | 554 | 2014-06-01 | 2024-08-20 |
| Phase 2 Study of Thermodox as Adjuvant Therapy With Thermal Ablation (RFA) in Treatment of Metastatic Colorectal Cancer(mCRC) Lyso-Thermosensitive Liposomal Doxorubicin, 5% Dextrose Solution, ThermoDox - Colon Cancer Liver Metastasis | Phase 2 | Terminated | Imunon | 2 | 2011-09-01 | 2022-10-13 |
| Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC) ThermoDox, 5% Dextrose Solution - Hepatocellular Carcinoma | Phase 3 | Completed | Imunon | 701 | 2008-05-01 | 2024-05-03 |
| A Study of ThermoDox™ in Combination With Radiofrequency Ablation (RFA) in Primary and Metastatic Tumors of the Liver ThermoDox - Hepatocellular Carcinoma, Liver Neoplasms | Phase 1 | Completed | Imunon | 30 | 2007-02-01 | 2019-02-07 |
Carcinoma, Hepatocellular (4) · Liver Neoplasms (4) · Carcinoma (2) · Hyperthermia (2) · Neoplasms (2) · Adenocarcinoma (1) · Breast Neoplasms (1) · Carcinoma, Ductal, Breast (1) · Colonic Neoplasms (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Liver Diseases (1) · Neoplasm Metastasis (1) · Neoplasms by Histologic Type (1) · Neoplasms by Site (1)
Imunon (4) · Children's National Research Institute (1) · UMC Utrecht (1) · University of Oxford (1)
United States (5) · Canada (2) · China (2) · Hong Kong (2) · Italy (2) · Malaysia (2) · Philippines (2) · South Korea (2) · Taiwan (2) · Thailand (2) · Germany (1) · Japan (1) · Netherlands (1) · Singapore (1) · Spain (1)
AeRang Kim, MD, PhD (1) · Britt BM Suelmann, MD (1) · Chen Min Hua, MD (1) · Mark Middleton (1) · Nicholas Borys, M.D. (1) · Ricardo Lencioni, MD (1) · Riccardo Lencioni, M.D. (1) · Ronnie T Poon, M.D. (1) · Ronnie Tung Ping Poon, MD (1)
2015 (1)