16 completed, 3 active not recruiting, 2 recruiting, 2 terminated. 9 Not applicable, 5 Phase 4, 3 Phase 1, 3 Phase 2, 3 Phase 3.
Follow this drug Literature Review of Technetium Tc 99m Sestamibi trials Research Report on Technetium Tc 99m Sestamibi
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast Cancer Tc99m sestamibi - Breast Cancer | Not applicable | Recruiting | M.D. Anderson Cancer Center | 300 | 2021-12-13 | 2026-10-06 |
| Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities Biopsy of Breast, Medical Device Usage and Evaluation, Scintimammography - Breast Neoplasm | Not applicable | Recruiting | Mayo Clinic | 70 | 2021-08-26 | 2026-10-05 |
| SPECT/CT for the Characterization of Renal Masses Computed Tomography, Questionnaire Administration, Single Photon Emission Computed Tomography - Kidney Neoplasm, Renal Mass | Active not recruiting | Jonsson Comprehensive Cancer Center | 102 | 2018-12-07 | 2026-03-13 | |
| DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancer Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Laboratory Biomarker Analysis, Scintimammography - Estrogen Receptor Negative, HER2/Neu Negative | Early Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 96 | 2016-11-07 | 2026-10-07 |
| 99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients 99mTc sestamibi - Thyroid Cancer | Phase 4 | Terminated | Medstar Health Research Institute | 4 | 2016-10-01 | 2022-07-26 |
| Tc99m Sestamibi Molecular Breast Imaging Molecular Breast Imaging (MBI), Tc99m sestamibi - Breast Cancer | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 96 | 2015-06-15 | 2026-09-16 |
| Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue Meal, Exercise, Sestamibi - Molecular Imaging | Phase 1 | Completed | Mayo Clinic | 154 | 2013-09-01 | 2017-04-18 |
| Stress and Rest Myocardial Tomoscintigraphies Using Mono- or Double-isotope Protocol With a Semiconductor Camera Tomoscintigraphy with D.SPECT camera (SPECTRUM Dynamics®, Israel), 99mTc-Sestamibi, Thallium-201 - Myocardial Perfusion | Not applicable | Completed | Central Hospital, Nancy, France | 118 | 2012-09-01 | 2016-08-16 |
| Half-Dose Radiopharmaceutical in Wide Beam Reconstruction Half-dose of the Tc99-m sestamibi (Cardiolite) - Myocardial Infarction, Ischemic Heart Disease | Not applicable | Terminated | Edwin Wu | 64 | 2011-10-01 | 2016-02-24 |
| A Phase 3 Multi-center Study to Assess PET Imaging of Flurpiridaz F 18 Injection in Patients With CAD. Flurpiridaz F18, 99mTechnicium (sestamibi or tetrofosmin) - Coronary Artery Disease | Phase 3 | Completed | Lantheus Medical Imaging | 795 | 2011-06-01 | 2020-11-24 |
| A Study of Regadenoson in Subjects Undergoing Stress Myocardial Perfusion Imaging (MPI) Using Multidetector Computed Tomography (MDCT) Compared to Single Photon Emission Computed Tomography (SPECT) regadenoson, technetium Tc99m sestamibi /technetium Tc99m tetrafosmin, Contrast - Coronary Artery Disease (CAD) | Phase 2 | Completed | Astellas Pharma Inc | 124 | 2011-04-26 | 2024-12-04 |
| Regadenoson Blood Flow in Type 1 Diabetes (RABIT1D) Regadenoson myocardial perfusion imaging, Regadenoson MRI myocardial blood flow - Coronary Artery Disease, Type 1 Diabetes Mellitus | Phase 4 | Completed | University of Colorado, Denver | 26 | 2009-11-01 | 2015-12-14 |
| Low Dose Molecular Breast Imaging as a Screening Tool for Women With Dense Breasts Molecular Breast Imaging, Conventional Mammography, Technetium (99mTc) sestamibi - Breast Cancer | Not applicable | Completed | Mayo Clinic | 1638 | 2009-04-01 | 2014-08-19 |
| Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI) regadenoson, overencapsulated caffeine, technetium - Coronary Artery Disease (CAD) | Phase 3 | Completed | Astellas Pharma Inc | 347 | 2009-03-24 | 2024-12-03 |
| Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Chest Pain Coronary Computed Tomography Angiography, Stress Nuclear Myocardial Perfusion Imaging - Coronary Artery Disease, Angina Pectoris | Not applicable | Completed | Montefiore Medical Center | 400 | 2008-07-01 | 2015-08-25 |
| Paclitaxel and CBT-1(Registered Trademark) to Treat Solid Tumors paclitaxel, CBT-1(Registered Trademark), Tc 99m sestamibi - Cervical, Ovarian | Not applicable | Completed | National Cancer Institute (NCI) | 12 | 2007-12-01 | 2012-07-19 |
| Radiation Therapy and Ammonium Tetrathiomolybdate in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer ammonium tetrathiomolybdate, immunoenzyme technique, laboratory biomarker analysis - Lung Cancer | Phase 1 | Withdrawn | Roswell Park Cancer Institute | 2007-05-01 | 2022-10-03 | |
| A Study to Evaluate the Use and Safety of CARDIOLITE® in Pediatric Patients With Kawasaki Disease Sestamibi - Kawasaki Disease | Phase 3 | Completed | Lantheus Medical Imaging | 445 | 2005-08-01 | 2019-07-23 |
| Molecular Breast Imaging as a Screening Tool for Women With Dense Breasts Molecular Breast Imaging, Conventional Mammography, Technetium (99mTc) sestamibi - Breast Cancer | Not applicable | Completed | Mayo Clinic | 969 | 2005-08-01 | 2014-08-01 |
| CARDIOLITE-413: A Study for Patients Who Had a PCI for an Acute MI Technetium Tc99m Sestamibi - Myocardial Infarction | Phase 4 | Completed | Lantheus Medical Imaging | 74 | 2005-01-01 | 2011-04-15 |
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Breast Neoplasms (5) · Coronary Artery Disease (5) · Ischemia (2) · Kidney Neoplasms (2) · Lung Neoplasms (2) · Mucocutaneous Lymph Node Syndrome (2) · Myocardial Infarction (2) · Acute Coronary Syndrome (1) · Adenocarcinoma of Lung (1) · Angina Pectoris (1) · Angina, Unstable (1) · Carcinoma, Non-Small-Cell Lung (1) · Coronary Restenosis (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 1 (1)
Lantheus Medical Imaging (6) · Mayo Clinic (4) · M.D. Anderson Cancer Center (3) · Astellas Pharma Inc (2) · National Cancer Institute (NCI) (2) · Central Hospital, Nancy, France (1) · Edwin Wu (1) · Jonsson Comprehensive Cancer Center (1) · Medstar Health Research Institute (1) · Montefiore Medical Center (1) · Roswell Park Cancer Institute (1) · University of Colorado, Denver (1)
United States (23) · Canada (5) · Brazil (2) · Puerto Rico (2) · Taiwan (2) · Finland (1) · France (1) · Philippines (1) · South Korea (1) · Thailand (1)
Qi Zhu, MD (3) · Beatriz Adrada (1) · Brian Shuch (1) · Cesare Orlandi, MD (1) · Deborah J Rhodes, M.D. (1) · Deborah J. Rhodes, M.D. (1) · Douglas Van Nostrand, MD (1) · Edwin Wu, M.D., FACC (1) · Gaiane M Rauch (1) · Gaiane M. Rauch, MD, PHD (1) · Jeffrey M Levsky, MD, PhD (1) · Katie N. Hunt, M.D. (1) · Linda B Haramati, MD, MS (1) · Martin Rosenberg, MD (1) · Michael K O'Connor, PhD, R-D (1)
PMID 21045179, PMID 21081657, PMID 21082298, PMID 22416063, PMID 24314823, PMID 25613340, PMID 25858045, PMID 26052677, PMID 30479286, PMID 32703509, PMID 35917778, PMID 36401636, PMID 37807004, PMID 38847615, PMID 41064867
P30CA016672 (1), R44CA143716 (1)