86 completed, 14 unknown, 6 withdrawn, 3 recruiting. 39 Phase 2, 23 Not applicable, 17 Phase 1, 16 Phase 4, 12 Early Phase 1.
Follow Syntocinon: new trials by email Literature Review of Syntocinon trials Research Report on Syntocinon
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Oxytocin Bolus Versus Slow Infusion on Haemodynamic Stability During Caesarean Section Under Spinal Anaesthesia Oxytocin - Cesarean Section, Hypotension | Not applicable | Not yet recruiting | Khyber Girls Medical College | 60 | 2026-09-01 | 2026-08-25 |
| Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial Carbetocin, Oxytocin, Placebo Saline Infusion - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Recruiting | Mansoura University | 332 | 2026-08-08 | 2026-10-09 |
| Effects of Intranasal Oxytocin on Sexual Well-Being in Patients With Arginine Vasopressin Deficiency and Healthy Controls Oxytocin nasal spray, Placebo - Arginine Vasopressin Deficiency, Central Diabetes Insipidus | Phase 2 | Recruiting | University Hospital, Basel, Switzerland | 42 | 2025-07-01 | 2025-10-03 |
| Oxytocin and Reward Processing in Women Intranasal oxytocin administration, Intranasal placebo administration - Menstrual Cycle, Hormonal Contraception | Not applicable | Recruiting | International Research Training Group 2804 | 100 | 2024-02-16 | 2024-02-28 |
| Oxytocin on Approach Bias and Craving Oxytocin, Placebo - Alcohol Use Disorder | Phase 2 | Withdrawn | Jennifer Mitchell | 2023-11-01 | 2022-06-06 | |
| Comparative Study Between Preoperative and Postoperative Rectal Misoprostol Misoprostol - Blood Loss, Surgical, Blood Loss, Postoperative | Not applicable | Completed | Egymedicalpedia | 128 | 2023-08-31 | 2024-08-20 |
| Carbetocin Compared To Oxytocin During Cesarean Delivery oxytocin, Carbetocin - Cesarean Delivery | Unknown | Assiut University | 260 | 2023-05-01 | 2023-03-07 | |
| Low-Dose Versus High-Dose Oxytocin Dosing for Induction and Augmentation of Labor Oxytocin (Low dose), Oxytocin (High dose) - Labor Long | Phase 4 | Completed | The University of Texas Medical Branch, Galveston | 170 | 2023-04-17 | 2026-01-09 |
| Blood Loss During Cesarean Delivery in Placenta Previa Patients Tranexamic acid, Misoprostol, Oxytocin - Placenta Previa | Phase 4 | Completed | Cairo University | 81 | 2022-05-04 | 2023-01-06 |
| Effects of Intranasal Oxytocin in the Treatment of Benzodiazepine Withdrawal: A Pilot RCT Oxytocin nasal spray, Saline (NaCl 0,9 %) (placebo) - Benzodiazepine Dependence | Phase 2 | Completed | St. Olavs Hospital | 66 | 2022-03-01 | 2026-09-28 |
| Carbetocin Versus Syntocinon for Prevention of Postpartum Hemorrhage in Cardiac Patients Undergoing Caesarean Section Syntocinon, Carbetocin - Adverse Effect of Oxytocic Drugs | Phase 4 | Unknown | Cairo University | 38 | 2021-11-30 | 2023-06-06 |
| Hemostatic Effect of Intrauterine Instillation of Oxytocin in Hysteroscopic Myomectomy Oxytocin, sterile bacteriostatic water ampule - Leiomyoma | Not applicable | Completed | Ain Shams Maternity Hospital | 60 | 2021-04-15 | 2023-11-07 |
| Prevention of Primary Postpartum Haemorrhage Misoprostol, Oxytocin - Primary, Post Partum Hemorrhage | Phase 2 | Unknown | Islamabad Medical and Dental College | 180 | 2021-02-03 | 2021-02-25 |
| Induction of Labor in Pregnant Women With Prelabor Rupture of Membranes - Oxytocin or Misoprostol Misoprostol, Syntocinon - Prelabor Rupture of Membranes | Phase 4 | Completed | Ain Shams Maternity Hospital | 200 | 2021-02-01 | 2022-06-23 |
| A Pharmaco-imaging Approach to Predicting Social Functioning and Clinical Responses to Oxytocin Administration in Schizophrenia Oxytocin, Placebo - Schizophrenia | Phase 2 | Terminated | VA Office of Research and Development | 26 | 2020-01-13 | 2026-01-20 |
| Oxytocin Treatment for Alcohol Use Disorders Oxytocin, Placebo - Alcohol Use Disorder | Phase 2 | Withdrawn | University of North Carolina, Chapel Hill | 2019-10-01 | 2019-11-13 | |
| Inhaled Oxytocin and HPA Axis Reactivity Intranasal Oxytocin, Placebo - Depression, Postpartum, Anxiety Disorders | Phase 2 | Completed | University of North Carolina, Chapel Hill | 109 | 2019-02-07 | 2025-08-08 |
| Intranasal Oxytocin and Food Intake in Obese Adolescents Syntocinon, Placebo - Obesity | Phase 2 | Withdrawn | Shana McCormack, MD | 2018-09-01 | 2018-12-26 | |
| Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Prader-Willi Syndrome Intranasal Oxytocin (IN-OXT), Matched Placebo - Prader-Willi Syndrome, Hyperphagia | Phase 2 | Completed | Eric Hollander | 32 | 2018-04-11 | 2025-02-07 |
| Intranasal Oxytocin for Frontotemporal Dementia Syntocinon - Frontotemporal Dementia | Phase 2 | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 112 | 2018-01-31 | 2023-12-15 |
Showing 20 of 113. Sign in to see all of them.
Autism Spectrum Disorder (11) · Postpartum Hemorrhage (11) · Schizophrenia (9) · Autistic Disorder (7) · Alcoholism (6) · Anxiety Disorders (5) · Obesity (5) · Prader-Willi Syndrome (5) · Diabetes Insipidus (4) · Stress Disorders, Post-Traumatic (4) · Substance-Related Disorders (4) · Depression, Postpartum (3) · Frontotemporal Dementia (3) · Hemorrhage (3) · Blood Loss, Surgical (2)
University of California, San Francisco (9) · Massachusetts General Hospital (8) · Ain Shams Maternity Hospital (4) · University of North Carolina, Chapel Hill (4) · Ain Shams University (3) · Cairo University (3) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (3) · University Hospital, Bonn (3) · Alexander Kolevzon (2) · Emory University (2) · Evdokia Anagnostou (2) · Holland Bloorview Kids Rehabilitation Hospital (2) · KU Leuven (2) · Norwegian University of Science and Technology (2) · Shana McCormack, MD (2)
United States (56) · Egypt (13) · Canada (10) · Germany (4) · Israel (4) · Norway (4) · Australia (2) · Belgium (2) · Pakistan (2) · Sweden (2) · Brazil (1) · China (1) · Denmark (1) · France (1) · Iran (1)
Josh D Woolley, MD/PhD (5) · Evdokia Anagnostou, M.D. (3) · David Mankuta, MD (2) · Eric Hollander, MD (2) · Gagan Joshi, MD (2) · Kaat Alaerts, PhD (2) · Lane Strathearn, MBBS PhD (2) · Olav Spigset, MD PhD (2) · Suma Jacob, M.D., Ph.D. (2) · Alexander Kolevzon, MD (1) · Alison M Stuebe, MD, MSc (1) · Allan L Reiss (1) · Allen Song, PhD (1) · Amanda Wang, MD (1) · Annie Dupuis, Ph.D. (1)
PMID 37811711, PMID 15931222, PMID 21862226, PMID 23216716, PMID 24734184, PMID 25224026, PMID 26994593, PMID 27137199, PMID 27314560, PMID 27350226, PMID 28416501, PMID 30189345, PMID 30261917, PMID 30606246, PMID 30784955, PMID 30791944, PMID 31477047, PMID 32053696, PMID 32963103, PMID 33112417, PMID 33543897, PMID 33587397, PMID 33853878, PMID 34593045, PMID 34697392, PMID 35141873, PMID 35358738, PMID 36239406, PMID 37442883, PMID 37883133, PMID 38445382, PMID 38767196, PMID 38815173, PMID 39862881, PMID 42714565
2015 (2), 1IK2CX001495-01 (1), 2004 (1), 2014 (1), 2019 (1), I01CX001761 (1), P50DA016511 (1), P50MH082999 (1), P50MH100023 (1), R01AA025942 (1), R01HD093901 (1), R01NR012899 (1), R21HD078778 (1), R21HD090396 (1), U54HD079124 (1)