sulforaphane: Clinical Trials

42 trials of sulforaphane, newest first

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21 completed, 9 unknown, 4 active not recruiting, 3 recruiting. 17 Not applicable, 17 Phase 2, 5 Phase 1, 3 Phase 4, 2 Phase 3.

By phase and status

PhaseTrialsStatus
Not applicable17Completed 10, Unknown 3, Enrolling by invitation 1, Not yet recruiting 1, Recruiting 1, Withdrawn 1
Phase 217Completed 8, Unknown 3, Active not recruiting 2, Recruiting 2, Terminated 1, Withdrawn 1
Phase 15Completed 3, Recruiting 1, Withdrawn 1
Phase 43Unknown 3
Phase 32Active not recruiting 1, Completed 1
Early Phase 11Active not recruiting 1

Follow sulforaphane: new trials by email Literature Review of sulforaphane trials Research Report on sulforaphane

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Mechanisms of Sulforaphane Supplementation in Alleviating Negative Symptoms and Cognitive Impairment in Schizophrenia
Placebo, Sulforaphane - Schizophrenia Disorder
Not applicableNot yet recruitingSecond Xiangya Hospital of Central South University602026-06-022026-06-18
Sulforaphane for the Prevention of Melanoma in Patients With Multiple Atypical Nevi and a Prior History of Melanoma
Biopsy Procedure, Biospecimen Collection, Placebo Administration - Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8
Phase 2RecruitingECOG-ACRIN Cancer Research Group1202026-02-202026-09-15
Safety and Feasibility of Sulforaphane to Promote Early Haematopoietic Recovery After Cord Blood Transplantation
Sulforaphane - ALL (Acute B-Lymphoblastic Leukemia), AML (Acute Myelogenous Leukemia
Not applicableRecruitingInstitute of Hematology & Blood Diseases Hospital, China362025-10-222025-12-30
Study of the Efficacy of Sulforaphane in Children Aged 6 to 12 With Attention Deficit Disorder With or Without Hyperactivity
Sulforaphane, Placebo - Attention Deficit Disorder
Not applicableUnknownAssistance Publique - Hôpitaux de Paris702024-12-012024-09-19
Mechanism Study of Sulforaphane in ASD Improvement
Sulforaphane - Autism Spectrum Disorder, Sulforaphane
Not applicableWithdrawnJian-Jun Ou2024-09-202025-09-04
Safety, Feasibility, and Tolerability of Sulforaphane in Children with Chronic Kidney Disease
Sulforaphane - Pediatric Kidney Disease
Phase 2Active not recruitingUniversity of Rochester122023-05-152024-09-19
Safety, Feasibility and Efficacy of Sulforaphane (Avmacol Extra Strength) in Chronic Kidney Disease
Sulforaphane (Avmacol Extra Strength), Placebo - Chronic Kidney Disease Stage 3, Chronic Kidney Disease Stage 4
Phase 2CompletedUniversity of Rochester962023-05-032026-05-18
Treatment Strategy to Enhance Nrf2 Signaling in Older Adults
Sulforaphane, Placebo capsules - Aging Problems
Not applicableCompletedNorthern Arizona University322023-02-092025-08-28
Validation Digital Bio-markers During Sulforaphane Treatment.
Sulforaphane - Autism, Autism Spectrum Disorder
Not applicableEnrolling by invitationRutgers, The State University of New Jersey102022-07-072025-10-30
Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol ES
Sulforaphane - Diastolic Dysfunction, Systolic Dysfunction
Phase 1 / Phase 2WithdrawnTexas Tech University Health Sciences Center2022-07-012026-06-29
Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction
sulforaphane, Placebo Oral Tablet - Anthracycline Related Cardiotoxicity in Breast Cancer
Phase 1 / Phase 2RecruitingTexas Tech University Health Sciences Center702022-06-012026-06-29
Study of Sulphoraphane in Chronic Kidney Disease
Sulforaphane - Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
Phase 1CompletedUniversity of Rochester182022-05-022024-08-12
Sulforaphane Use to Effect Inflammatory and Metabolic Changes in Virally Suppressed HIV Patients
Sulforaphane, Placebo - HIV Infections
Phase 4UnknownSunshine Specialty Health Care202022-02-212022-02-07
A 6-month Study to Evaluate Sulforaphane Effects in PD Patients
Sulforaphane, Placebo - Parkinson Disease
Phase 2UnknownCentral South University1002021-11-282023-07-06
The PROtective Effect of SulforAphaNe on Chronic Low-grade Inflammation in Healthy Participants
BroccoCress, Affilla Cress - Inflammation
Not applicableCompletedMaastricht University Medical Center122021-11-112022-04-13
Effect of Broccoli Sprout Extract in Patients With Chronic Kidney Disease With Diabetes Type 2
Sulforaphane, administered as Broccoli sprout extract - Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4
Not applicableCompletedKarolinska Institutet1002021-10-102024-03-04
Open-Label Trial of Sulforaphane in Premutation Carriers With FXTAS
Sulforaphane - Fragile X Associated Tremor/Ataxia Syndrome (Fxtas) (Diagnosis)
Not applicableCompletedUniversity of California, Davis152021-06-252023-07-12
A 6-month Study to Evaluate Sulforaphane Effects in Schizophrenia Patients
Sulforaphane, placebo - Schizophrenia
Phase 2CompletedCentral South University1252020-08-312023-04-26
A 12-weeks Study to Evaluate Sulforaphane in the Treatment of Depression
sulforaphane, placedo, selective 5 - HT reuptake inhibitors (SSRI) - Depressive Disorder
Phase 2UnknownCentral South University902020-07-152020-08-20
Effects of Sulforaphane on Cognitive Function in Patients With Frontal Brain Damage
sulforaphane, placedo - Frontal Lobe Dysfunction
Phase 2UnknownXiangya Hospital of Central South University902020-06-012020-05-19

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Conditions studied

Autism Spectrum Disorder (6)  ·  Autistic Disorder (4)  ·  Schizophrenia (3)  ·  Diabetes Mellitus, Type 2 (2)  ·  Prostatic Neoplasms (2)  ·  Renal Insufficiency, Chronic (2)  ·  Alzheimer Disease (1)  ·  Anemia, Refractory, with Excess of Blasts (1)  ·  Attention Deficit Disorder with Hyperactivity (1)  ·  Cardiotoxicity (1)  ·  Child Development Disorders, Pervasive (1)  ·  Cognition Disorders (1)  ·  Cystic Fibrosis (1)  ·  Depression (1)  ·  Depressive Disorder (1)

Sponsors

Central South University (5)  ·  University of Rochester (3)  ·  Johns Hopkins University (2)  ·  Rutgers, The State University of New Jersey (2)  ·  Texas Tech University Health Sciences Center (2)  ·  Anders Rosengren, MD PhD (1)  ·  Assistance Publique - Hôpitaux de Paris (1)  ·  ECOG-ACRIN Cancer Research Group (1)  ·  Institute of Hematology & Blood Diseases Hospital, China (1)  ·  Jian-Jun Ou (1)  ·  Jian-Min Yuan, MD (1)  ·  Karolinska Institutet (1)  ·  Kyunghee University Medical Center (1)  ·  Maastricht University Medical Center (1)  ·  Northern Arizona University (1)

Countries

United States (20)  ·  China (10)  ·  United Kingdom (3)  ·  Netherlands (1)  ·  South Korea (1)  ·  Sweden (1)

Top investigators

Anna Chien (2)  ·  Renrong Wu, M.D Ph.D (2)  ·  Alexander MacGregor, PhD (1)  ·  Anders Rosengren (1)  ·  Andrew W Zimmerman, MD (1)  ·  Carla Avesani, PhD (1)  ·  Daomeng Cheng, M.D. (1)  ·  David Heber, MD, PhD (1)  ·  David L Eaton, PhD (1)  ·  Fang Dong (1)  ·  Fengyu Zhang, Ph.D. (1)  ·  Hua Jin, M.D Ph.D (1)  ·  Hua Jin, M.D., Ph. D. (1)  ·  Hua Jin, PhD (1)  ·  Jackilen Shannon, PhD (1)

Results publications

PMID 24287881, PMID 25313065, PMID 28615356, PMID 29854372, PMID 31155953, PMID 32242086, PMID 33067279, PMID 34034808, PMID 37485383, PMID 38089924, PMID 39832347, PMID 40041932, PMID 41099966, PMID 41802185

NIH funding

R01DK128677 (2), 5KL2TR001109-05 (1), P01CA090890 (1), R01CA213123 (1), UG1CA189828 (1)