20 completed, 11 unknown, 10 recruiting, 5 terminated. 52 Phase 3, 15 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 52 | Completed 20, Unknown 11, Recruiting 10, Terminated 5, Active not recruiting 4, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 15 | Unknown 7, Completed 4, Recruiting 2, Terminated 2 |
Follow Standard Therapy: new trials by email Literature Review of Standard Therapy trials Research Report on Standard Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia Best Practice, Biospecimen Collection, Cytarabine - Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia | Phase 3 | Recruiting | Children's Oncology Group | 556 | 2026-08-14 | 2026-09-04 |
| SGLT2 Inhibitors in Adult Primary Nephrotic Syndrome Dapagliflozin, Empagliflozin, Standard Therapy - Nephrotic Syndrome | Phase 2 / Phase 3 | Recruiting | Mansoura University | 75 | 2025-11-15 | 2026-06-09 |
| Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity Standard of Care Chemotherapy, Biospecimen Collection, Computed Tomography - Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma | Phase 2 / Phase 3 | Recruiting | ECOG-ACRIN Cancer Research Group | 148 | 2025-10-24 | 2026-10-05 |
| Nanocrystalline Megestrol Acetate in Concurrent Chemoradiotherapy for Locally Advanced Non-Small Cell Lung Cancer Nano-crystalline Megestrol Acetate Oral Suspension, Standard Therapy - Non-small Cell Lung Cancer | Phase 3 | Recruiting | Changchun GeneScience Pharmaceutical Co., Ltd. | 134 | 2025-08-20 | 2025-09-08 |
| Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease Tocilizumab, Nintedanib, Standard therapy - Systemic Sclerosis, Interstitial Lung Disease | Phase 3 | Recruiting | National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland | 86 | 2025-07-01 | 2026-04-08 |
| Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy Autologous Hematopoietic Stem Cell Transplantation, Best Practice, Biospecimen Collection - Anaplastic Large Cell Lymphoma, ALK-Negative, Follicular Helper T-Cell Lymphoma | Phase 3 | Recruiting | Eastern Cooperative Oncology Group | 294 | 2025-06-18 | 2026-09-14 |
| Clinical Study on Nanocrystalline Megestrol Acetate for Appetite Improvement and Weight Gain in Pre-Cachexia and Cachexia Stages Key Terminology Analysis Nano-crystalline Megestrol Acetate Oral Suspension, Standard Therapy - Metastatic (Stage IV) Non-squamous Non-small Cell Lung Cancer (Nsq-NSCLC) With Driver Gene Negativity, Untreated With Systemic Therapy | Phase 3 | Not yet recruiting | Changchun GeneScience Pharmaceutical Co., Ltd. | 174 | 2025-06-01 | 2025-05-07 |
| Comparing Radiation Therapy to Usual Treatment for Patients With High-Risk Bone Metastases That Are Not Causing Pain, PREEMPT Trial Best Practice, Biospecimen Collection, Bone Metastases Treatment - Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm | Phase 3 | Active not recruiting | NRG Oncology | 280 | 2025-05-07 | 2026-08-17 |
| Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer Best Practice, Biospecimen Collection, Electronic Health Record Review - Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | Phase 3 | Recruiting | Children's Oncology Group | 60 | 2025-02-27 | 2026-08-31 |
| Clinical Outcome of Vinpocetine in Diabetic Nephropathy Vinpocetine, Standard Therapy, Placebo - Diabetic Kidney Disease, Diabetic Nephropathies | Phase 2 / Phase 3 | Unknown | Ain Shams University | 64 | 2024-07-10 | 2024-07-11 |
| Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial Best Practice, Comprehensive Geriatric Assessment, Educational Intervention - Lymphoma, Malignant Solid Neoplasm | Phase 3 | Recruiting | University of Rochester | 668 | 2023-03-21 | 2026-01-13 |
| Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Mild COVID-19 MIR 19 ®, Standard therapy - COVID-19 | Phase 2 / Phase 3 | Completed | National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia | 984 | 2022-02-10 | 2023-12-27 |
| Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer. All trans-retinoic acid, 13-Cis Retinoic Acid plus Tocopherol, Mifepristone - Breast Cancer Female | Phase 3 | Unknown | Mahmoud Ramadan mohamed Elkazzaz | 160 | 2021-08-01 | 2021-08-23 |
| Study of Efficacy of Different Treatment Regimens of Olokizumab Olokizumab, Standard therapy - COVID-19 | Phase 3 | Unknown | R-Pharm | 198 | 2021-07-08 | 2023-02-13 |
| The Benefits of Vitamin D 5000 IU as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient Standard therapy, Vitamin D 5,000IU Oral Tablet - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Duta Wacana Christian University | 60 | 2020-11-03 | 2020-12-30 |
| The Benefits of Astaxanthin as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient Standard therapy, Astaxanthin - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Duta Wacana Christian University | 60 | 2020-11-03 | 2020-12-30 |
| The Benefits of Vitamin B Combination as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient Standard therapy, Vitamin B combination - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Duta Wacana Christian University | 60 | 2020-11-03 | 2020-12-30 |
| Self-Management Program and Survivorship Care Plan in Improving the Health of Cancer Survivors After Stem Cell Transplant Best Practice and Internet site with links to existing resources, Internet, Mobile app and Telehealth Intervention, Survey Administration - Hematopoietic and Lymphoid Cell Neoplasm | Phase 3 | Completed | Fred Hutchinson Cancer Center | 546 | 2020-10-29 | 2025-01-29 |
| Convalescent Plasma for Patients With COVID-19: A Randomized, Single Blinded, Parallel, Controlled Clinical Study Plasma, Standard Therapy - Coronavirus, Coronavirus Infection | Phase 2 / Phase 3 | Completed | Universidad del Rosario | 92 | 2020-08-08 | 2020-11-27 |
| Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19 Best Practice, Low Dose Radiation Therapy - Pneumonia, Severe Acute Respiratory Syndrome | Phase 3 | Unknown | Emory University | 14 | 2020-06-23 | 2023-08-14 |
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COVID-19 (7) · Acute Coronary Syndrome (3) · Diabetic Neuropathies (3) · Lupus Erythematosus, Systemic (3) · Prostatic Neoplasms (3) · Autoimmune Diseases (2) · Carcinoma, Non-Small-Cell Lung (2) · Cardiovascular Diseases (2) · Coronavirus Infections (2) · Diabetes Mellitus (2) · Hematologic Neoplasms (2) · Neoplasm Metastasis (2) · Neoplasms (2) · Proteinuria (2) · Pulmonary Disease, Chronic Obstructive (2)
Children's Oncology Group (3) · Duta Wacana Christian University (3) · Alliance for Clinical Trials in Oncology (2) · Changchun GeneScience Pharmaceutical Co., Ltd. (2) · Emory University (2) · Fred Hutchinson Cancer Center (2) · GlaxoSmithKline (2) · Human Genome Sciences Inc., a GSK Company (2) · University of Catanzaro (2) · Abramson Cancer Center at Penn Medicine (1) · Ain Shams University (1) · Brooke Army Medical Center (1) · CardioRenal Systems, Inc. (1) · Dexa Medica Group (1) · ECOG-ACRIN Cancer Research Group (1)
United States (26) · Canada (8) · Germany (7) · Italy (6) · Russia (6) · Argentina (5) · Brazil (5) · China (5) · France (5) · Mexico (5) · United Kingdom (5) · Belgium (4) · Colombia (4) · Czechia (4) · Hungary (4)
Rizaldy T Pinzon, MD, MSc, PhD (2) · A. L Frazier (1) · Ajay K Nooka (1) · Amr Ahmed (1) · Charles Davidson, MD (1) · Cristina DeCesaris, MD (1) · Deba P Dhibar, MD (1) · Didier Payen, MD (1) · Eric J Chow (1) · Erin F Gillespie (1) · Fengchun Zhang, M.D. (1) · Iver A Langmoen, MD, PhD (1) · Janice Mehnert (1)
PMID 20671225, PMID 21982651, PMID 23817721, PMID 25030060, PMID 25173516, PMID 25862039, PMID 25965709, PMID 26618098, PMID 27043082, PMID 28077384, PMID 28118533, PMID 29018021, PMID 29671280, PMID 29807477, PMID 30081846, PMID 30371283, PMID 30615259, PMID 30616601, PMID 31488402, PMID 32129478, PMID 32691060, PMID 32871021, PMID 32937045, PMID 33386288, PMID 33558436, PMID 33568389, PMID 33687069, PMID 34508693, PMID 34531304, PMID 34560137, PMID 34890060, PMID 34984028, PMID 35226080, PMID 35283454, PMID 35292232, PMID 35761219, PMID 36058429, PMID 36302567, PMID 37017254, PMID 37228028, PMID 37463054, PMID 37783480, PMID 38018702, PMID 38216728, PMID 38724182, PMID 39115551, PMID 39208825, PMID 40244828, PMID 41092329, PMID 41698328
U10CA180820 (3), P30CA138292 (2), UG1CA189955 (2), R01CA215134 (1), R01CA227092 (1), R01CA243914 (1), R01CA249467 (1), U10CA180886 (1), U24CA196173 (1), UG1CA189867 (1), UG1CA189961 (1), UG1CA189974 (1)