12 recruiting, 4 completed, 2 not yet recruiting, 1 active not recruiting. 21 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 21 | Recruiting 12, Completed 4, Not yet recruiting 2, Active not recruiting 1, Suspended 1, Terminated 1 |
| Phase 1 | 3 | Recruiting 2, Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Single Photon Emission Computed Tomography: new trials by email Literature Review of Single Photon Emission Computed Tomography trials Research Report on Single Photon Emission Computed Tomography
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pluvicto for the Treatment of African American Men With Metastatic Castration-Resistant Prostate Cancer Biopsy Procedure, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Not yet recruiting | Emory University | 88 | 2026-11-02 | 2026-10-06 |
| Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial Abiraterone Acetate, Biospecimen Collection, Leuprolide Acetate - Recurrent Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Recruiting | Mayo Clinic | 202 | 2026-08-04 | 2026-09-18 |
| Y-90 Radioembolization, Durvalumab, Tremelimumab, and Zanzalintinib for the Treatment of Unresectable and Locally-Advanced Hepatocellular Carcinoma Angiogram, Biopsy Procedure, Biospecimen Collection - Locally Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8 | Phase 2 | Not yet recruiting | OHSU Knight Cancer Institute | 40 | 2026-04-02 | 2026-04-06 |
| Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial Biospecimen Collection, Carboplatin, Cisplatin - Oral Cavity Squamous Cell Carcinoma, Stage I Lip and Oral Cavity Cancer AJCC v8 | Phase 2 | Recruiting | University of Michigan Rogel Cancer Center | 50 | 2025-07-17 | 2026-07-31 |
| Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease Biospecimen Collection, Bone Scan, Computed Tomography - Metastatic Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Recruiting | University of Washington | 51 | 2025-04-29 | 2026-07-07 |
| Yttrium-90 (Y90) Radioembolization for the Treatment of Early Stage Renal Cell Carcinoma, The RENEGADE Trial Angiogram, Biospecimen Collection, Computed Tomography - Stage I Renal Cell Cancer, Stage II Renal Cell Cancer | Phase 1 / Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 25 | 2024-12-26 | 2026-08-21 |
| Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer Biopsy Procedure, Biospecimen Collection, Bone Scan - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 15 | 2024-09-18 | 2026-08-06 |
| Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial Biospecimen Collection, Computed Tomography, Gallium Ga 68 Gozetotide - Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 40 | 2024-08-01 | 2026-03-13 |
| Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT) Computed Tomography, Gallium Ga 68 Gozetotide, Lutetium Lu 177 Vipivotide Tetraxetan - Prostate Carcinoma, Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 90 | 2024-08-01 | 2026-03-10 |
| Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study Biopsy Procedure, Biospecimen Collection, Bone Scan - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma | Phase 2 | Recruiting | University of Washington | 69 | 2024-05-21 | 2026-07-21 |
| Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer Biospecimen Collection, Bone Scan, Clinical Observation - Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Suspended | Mayo Clinic | 236 | 2024-05-03 | 2026-08-20 |
| Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors Biospecimen Collection, Computed Tomography, Everolimus - Advanced Lung Neuroendocrine Tumor, Functioning Lung Neuroendocrine Tumor | Phase 2 | Recruiting | National Cancer Institute (NCI) | 70 | 2023-02-03 | 2026-11-05 |
| Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer Chest Radiography, Computed Tomography, Fludeoxyglucose F-18 - Buccal Mucosa Squamous Cell Carcinoma, Floor of Mouth Squamous Cell Carcinoma | Phase 2 / Phase 3 | Recruiting | NRG Oncology | 686 | 2020-09-23 | 2026-08-17 |
| Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones Biospecimen Collection, Bone Scan, Computed Tomography - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Negative Breast Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 70 | 2020-08-04 | 2026-09-18 |
| Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation Therapy Gallium Ga 68-DOTATATE, Lutetium Lu 177 Dotatate, Magnetic Resonance Imaging - Grade 1 Meningioma, Grade 2 Meningioma | Phase 2 | Recruiting | Mayo Clinic | 42 | 2020-04-14 | 2026-10-13 |
| 211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia Cyclosporine, Fludarabine Phosphate, Mycophenolate Mofetil - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Phase 1 / Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 75 | 2017-10-24 | 2026-06-22 |
| FLARE RT for Patients With Stage IIB-IIIB Non-small Cell Lung Cancer: Personalizing Radiation Therapy Using PET/CT and SPECT/CT Imaging Computed Tomography, Fludeoxyglucose F-18, Laboratory Biomarker Analysis - Stage IIB Lung Non-Small Cell Carcinoma AJCC v7, Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Phase 2 | Completed | University of Washington | 51 | 2016-05-20 | 2024-08-14 |
| A Study of Regadenoson in Subjects Undergoing Stress Myocardial Perfusion Imaging (MPI) Using Multidetector Computed Tomography (MDCT) Compared to Single Photon Emission Computed Tomography (SPECT) regadenoson, technetium Tc99m sestamibi /technetium Tc99m tetrafosmin, Contrast - Coronary Artery Disease (CAD) | Phase 2 | Completed | Astellas Pharma Inc | 124 | 2011-04-26 | 2024-12-04 |
| Zoledronic Acid and Positron Emission Tomography in Treating Patients With Advanced Non-Small Cell Lung Cancer 3'-deoxy-3'-[18F]FLT, Single photon emission computed tomography - Lung Cancer, Metastatic Cancer | Phase 2 | Terminated | Barbara Ann Karmanos Cancer Institute | 6 | 2008-03-01 | 2015-02-04 |
| Study of Coronary Artery Computed Tomography to Diagnose Emergency Chest Pain coronary artery computed tomography angiogram, single photon emission computed tomography - Chest Pain, Angina Pectoris | Phase 2 | Completed | Corewell Health East | 200 | 2005-03-01 | 2006-01-09 |
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Prostatic Neoplasms (8) · Carcinoma, Non-Small-Cell Lung (2) · Mouth Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Anemia, Refractory, with Excess of Blasts (1) · Angina Pectoris (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Renal Cell (1) · Chest Pain (1) · Coronary Artery Disease (1) · Ischemia (1) · Leukemia, Biphenotypic, Acute (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myeloid, Acute (1) · Leukemia, Myelomonocytic, Chronic (1)
Mayo Clinic (4) · Jonsson Comprehensive Cancer Center (3) · University of Washington (3) · Fred Hutchinson Cancer Center (2) · National Cancer Institute (NCI) (2) · Astellas Pharma Inc (1) · Barbara Ann Karmanos Cancer Institute (1) · Corewell Health East (1) · Emory University (1) · NRG Oncology (1) · OHSU Knight Cancer Institute (1) · University of Michigan Rogel Cancer Center (1)
United States (21) · Canada (1)
Michael Schweizer (2) · Adel Kardosh (1) · Angela Castellanos Rodriguez, MD, MSc (1) · Brenda M. Sandmaier (1) · Gilbert L Raff, MD (1) · Jacob E Berchuck, MD (1) · Jennifer L Shah (1) · Jeremie Calais (1) · Jeremie Calais, MD (1) · Jing Zeng (1) · Kenneth W. Merrell, MD (1) · Matthew K. Tollefson, MD (1) · Matthew P. Thorpe, M.D., Ph.D. (1) · Scott M Glaser (1)
PMID 17320744, PMID 24314823, PMID 30335787, PMID 31142507, PMID 33027064, PMID 34172602, PMID 38981590, PMID 40876952, PMID 41276366, PMID 41679923
P01CA078902 (1), P30CA015083 (1), P30CA022453 (1), P30CA138292 (1), P50CA097186 (1), R01CA204301 (1), R37CA286450 (1), U10CA180821 (1), U10CA180868 (1), UM1CA186644 (1), UM1CA186716 (1)