7 not yet recruiting, 4 completed, 3 recruiting, 1 unknown. 14 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Not yet recruiting 7, Completed 4, Recruiting 3 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Sham photobiomodulation: new trials by email Literature Review of Sham photobiomodulation trials Research Report on Sham photobiomodulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Can Acute Photobiomodulation Improve Balance and Cognition in Individuals With Ataxia: a Pilot Feasibility Placebo Randomized Controlled Trial. Photobiomodulation, Sham photobiomodulation - Ataxia | Not applicable | Not yet recruiting | University of Central Lancashire | 20 | 2027-01-01 | 2026-09-22 |
| Photobiomodulation After Nonsurgical Root Canal Treatment Adjunctive Photobiomodulation, Sham Photobiomodulation - Symptomatic Apical Periodontitis, Postoperative Pain | Not applicable | Not yet recruiting | University of Minnesota | 60 | 2026-10-19 | 2026-10-21 |
| Photobiomodulation Laser for Reticular Pseudodrusen in Age-Related Macular Degeneration Photobiomodulation Therapy, Sham Photobiomodulation - AMD - Age-Related Macular Degeneration | Not applicable | Not yet recruiting | Fondazione G.B. Bietti, IRCCS | 67 | 2026-10-01 | 2026-09-04 |
| Increasing Mitochondrial Respiration as a Novel Mechanism for Cognitive Augmentation Active transcranial photobiomodulation, Active MCT dietary supplementation, Sham photobiomodulation - Cognition Improvement, Emotion Regulation | Not applicable | Not yet recruiting | Francisco Gonzalez-Lima, PhD | 180 | 2026-10-01 | 2026-08-28 |
| Neuromodulation Combined With Dual FES Cycling and Cognitive Training After Stroke Functional Electrical Stimulation Cycling, Cognitive Task Training, Transcutaneous Auricular Photobiomodulation - Stroke | Not applicable | Not yet recruiting | Chang Gung Memorial Hospital | 150 | 2026-10-01 | 2026-09-08 |
| Photobiomodulation Effects on Blood Pressure and Vascular Function in Treated Hypertensive Patients Vascular Photobiomodulation, Sham Photobiomodulation - Hypertension | Not applicable | Recruiting | University of Nove de Julho | 80 | 2026-09-01 | 2026-09-09 |
| Photobiomodulation for Median Nerve Neuroplasticity in Carpal Tunnel Syndrome: A Randomized Controlled Trial Photobiomodulation (Low-Level Laser Therapy), Sham Photobiomodulation, Routine Physiotherapy Programme - Carpal Tunnel Syndrome (CTS) | Not applicable | Not yet recruiting | University of Lahore | 70 | 2026-08-15 | 2026-07-20 |
| Effect of Photobiomodulation on Healing of Venous Leg Ulcers Photobiomodulation Therapy, Sham Photobiomodulation, Compression Therapy - Venous Leg Ulcer (VLU), Venous Hypertension Ulcers | Not applicable | Recruiting | University of Nove de Julho | 102 | 2026-08-03 | 2026-09-09 |
| Effects of Photobiomodulation With Superpulsed Laser and Dual Wavelengths in Children and Adolescents Active Photobiomodulation, Sham Photobiomodulation - Facial Pain, Headache | Not applicable | Not yet recruiting | University of Nove de Julho | 60 | 2025-07-01 | 2025-06-22 |
| Biomodulation and Rehabilitation Interventions to tarGet Pelvic Health Photobiomodulation, Sham photobiomodulation, Multimodal physiotherapy - Vulvodynia, Provoked Vestibulodynia | Not applicable | Recruiting | University of Ottawa | 240 | 2025-03-17 | 2026-05-05 |
| Laser Photobiomodulation After Dental Implant Surgery: A Comparison of 650 nm and 810 nm Diode Lasers 650 nm Diode Laser PBM, 810 nm Diode Laser PBM, Sham Laser PBM - Postoperative Pain, Dental Implant | Not applicable | Completed | National Institute of Laser Enhanced Sciences | 60 | 2023-08-17 | 2025-05-25 |
| Photobiomodulation on NMES-Induced Muscle Fatigue and Damage Photobiomodulation Therapy (PBMT), Sham Photobiomodulation - Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Federal University of Rio Grande do Sul | 12 | 2022-11-01 | 2026-08-31 |
| Effect of Photobiomodulation on Orthodontic Tooth Movement 635-nm photobiomodulation, Sham photobiomodulation - Class II Malocclusion, Orthodontic Tooth Movement | Not applicable | Completed | Wroclaw Medical University | 18 | 2021-01-05 | 2026-02-10 |
| Effect of Photobiomodulation on the Treatment of Soft Tissue Traumatic Injuries Photobiomodulation, Sham Photobiomodulation - Soft Tissue Injuries | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 84 | 2020-05-30 | 2020-04-24 |
| Physiotherapy Treatment for Chronic Achilles Tendinopathy Low-level Laser Therapy, Sham Low-level Laser Therapy, Exercise therapy - Achilles Tendinopathy | Not applicable | Completed | University of Bergen | 41 | 2017-08-01 | 2020-10-27 |
Pain, Postoperative (2) · Agnosia (1) · Ataxia (1) · Carpal Tunnel Syndrome (1) · Dental Pulp Diseases (1) · Dyspareunia (1) · Emotional Regulation (1) · Facial Pain (1) · Headache (1) · Hyperalgesia (1) · Hypertension (1) · Macular Degeneration (1) · Overbite (1) · Soft Tissue Injuries (1) · Stroke (1)
University of Nove de Julho (4) · Chang Gung Memorial Hospital (1) · Federal University of Rio Grande do Sul (1) · Fondazione G.B. Bietti, IRCCS (1) · Francisco Gonzalez-Lima, PhD (1) · National Institute of Laser Enhanced Sciences (1) · University of Bergen (1) · University of Central Lancashire (1) · University of Lahore (1) · University of Minnesota (1) · University of Ottawa (1) · Wroclaw Medical University (1)
Brazil (3) · United States (2) · Canada (1) · Egypt (1) · Italy (1) · Norway (1) · Pakistan (1) · Poland (1) · United Kingdom (1)
Chia-Ling Chen (1) · Dr Ashfaq Ahmad, PhD (1) · Dr Ishaq Ahmed, PhD (1) · Dr Sajid Mehmood, MS (OMPT) (1) · Dr Umair Ahmed, PhD (1) · Ingvill F Naterstad, MSc (1) · Linda McLean, PhD (1) · Marco A Vaz, PhD (1) · Mohammad M Abdussalam, BDS, MSc (1) · Raphael Dias, PhD (1) · Ronald Ordinola-Zapata (1) · Stephanie Bernard, PhD (1)