68 completed, 21 unknown, 11 recruiting, 7 not yet recruiting. 78 Not applicable, 12 Phase 4, 8 Phase 2, 8 Phase 3, 4 Phase 1.
Follow Scaling and Root Planing: new trials by email Literature Review of Scaling and Root Planing trials Research Report on Scaling and Root Planing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alb-PRF as an Adjunct to Nonsurgical Periodontal Therapy Nonsurgical Periodontal Therapy, Albumin Platelet-Rich Fibrin - Periodontitis | Not applicable | Not yet recruiting | Halil Ata BIÇAKÇIOĞLU | 24 | 2026-12-01 | 2026-08-31 |
| Photodynamic Therapy as an Adjunct in Periodontal Treatment Scaling and Root Planing, Antimicrobial Photodynamic Therapy - Periodontitis, Periodontal Disease | Not applicable | Enrolling by invitation | Universidad Catolica Santiago de Guayaquil | 30 | 2026-07-28 | 2026-09-25 |
| Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial scaling and root planing - Periodontitis, Adult, Periodontal Diseases | Not applicable | Not yet recruiting | Zeyad Nazar | 21 | 2026-07-15 | 2026-05-19 |
| Hyaluronic Acid as an Adjunct to Non-Surgical Periodontal Therapy in Smokers Scaling and Root Planing, Hyaluronic Acid (HYADENT BG) - Hyaluronic Acid, Periodontal Therapy | Not applicable | Recruiting | Marmara University | 23 | 2026-07-13 | 2026-08-18 |
| NON-SURGİCAL PERİODONTAL THERAPY WİTH L-ARGİNİNE L-arginine 0.8% subgingival irrigation, Saline 0.9% subgingival irrigation (placebo), Scaling and root planing - Periodontal Disease, Periodontal Diseases | Not applicable | Active not recruiting | Alanya Alaaddin Keykubat University | 60 | 2026-06-01 | 2026-10-23 |
| Adjunctive Hyaluronic Acid Gel in Non-Surgical Periodontal Treatment of Patients With Diabetes Mellitus Scaling and root planing, Hyaluronic Acid (HYADENT BG) - Periodontitis, Diabetes Mellitus | Not applicable | Not yet recruiting | Marmara University | 23 | 2026-06-01 | 2026-06-08 |
| Periodontal Inflammation and Epigenetics in Obese Individuals Non-surgical periodontal therapy will be administered - Obesity, Periodontitis | Not applicable | Not yet recruiting | Louisiana State University Health Sciences Center in New Orleans | 40 | 2026-05-25 | 2026-05-28 |
| This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients Injectable Platelet-Rich Fibrin (I-PRF), Diode Laser Activation, Povidone-Iodine Irrigation (1%) - Periodontitis, Smokers | Phase 4 | Recruiting | Military Hospital of Tunis | 50 | 2026-05-25 | 2026-07-16 |
| Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus Scaling and root planing, Photodynamic Therapy with Conventional Methylene Blue - Type 2 Diabetes, Halitosis | Not applicable | Recruiting | University of Sao Paulo | 32 | 2026-04-02 | 2026-03-16 |
| Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics local antibiotic application of topical minocycline, Scaling and Root Planing - Periodontitis, Diabetes Mellitus Type 2 | Early Phase 1 | Recruiting | Case Western Reserve University | 42 | 2026-02-06 | 2026-02-19 |
| Effect of Morus Nigra Mouthwash on Gingivitis Treatment Scaling and Root Planing, Morus Nigra Mouthwash - Gingivitis | Not applicable | Recruiting | Inonu University | 30 | 2026-01-15 | 2026-04-13 |
| Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients Scaling and Root Planing, Diode Laser - Periodontitis, Kidney Transplant Recipients | Not applicable | Recruiting | Military Hospital 103 | 80 | 2025-12-09 | 2026-04-16 |
| Advanced Platelet-Rich Fibrin Plus in Nonsurgical Periodontal Therapy Scaling and Root Planing, Advanced Platelet-Rich Fibrin Plus - Periodontitis | Not applicable | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 14 | 2025-10-03 | 2026-08-24 |
| Minimally Invasive Non- Surgical Periodontal Therapy of Intrabony Defects: Healing Patterns and Smoking Impact Minimally Invasive Non- Surgical Periodontal Therapy (MINST), conventional Non-Surgical Periodontal Treatment (cNSPT) - Periodontitis | Not applicable | Not yet recruiting | University of Turku | 120 | 2025-09-01 | 2025-08-19 |
| Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols Scaling and Root Planing, antibiotic prophylaxis, 810nm Diode Laser - Periodontitis | Not applicable | Recruiting | National and Kapodistrian University of Athens | 75 | 2025-08-25 | 2025-09-04 |
| The Efficacy of Salvia Officinalis Gel in the Treatment of Periodontitis CLINICAL TRIAL Salvia officinalis Gel - Periodontal Pocket | Not applicable | Not yet recruiting | University of Baghdad | 23 | 2025-05-01 | 2025-03-28 |
| Hyaluronic Acid and Albumin-PRF in Non-Surgical Periodontal Therapy Non-Surgical Periodontal Treatment, Albumin Platelet-Rich Fibrin (Alb-PRF), Hyaluronic Acid Gel - Periodontitis, Periodontal Inflammation | Not applicable | Completed | Inonu University | 51 | 2025-04-09 | 2026-07-07 |
| The Efficacy of Scaling and Root Planing on Endothelin-1 Level Scaling and root surface debritment - Periodontitis | Not applicable | Not yet recruiting | University of Baghdad | 24 | 2025-02-01 | 2025-01-20 |
| Active Oxygen Releasing Gel With Photodynamic Therapy in Treating Stage III Periodontitis Scaling and root planing, topical active oxygen-releasing gel, and photodynamic therapy using diode laser, Scaling and root planing and topical application of active oxygen-releasing gel, Scaling and root planing - Stage III Periodontitis | Not applicable | Recruiting | Alexandria University | 42 | 2025-01-26 | 2026-10-09 |
| Effectiveness of Scaling and Root Planing in Deeper Pockets Scaling and root planing - Periodontal Disease, Periodontitis | Active not recruiting | Texas A&M University | 110 | 2025-01-01 | 2025-12-09 |
Showing 20 of 117. Sign in to see all of them.
Periodontitis (72) · Chronic Periodontitis (32) · Periodontal Diseases (30) · Gingivitis (7) · Periodontal Pocket (7) · Diabetes Mellitus (6) · Diabetes Mellitus, Type 2 (6) · Smoking (4) · Arthritis, Rheumatoid (3) · Inflammation (3) · Obesity (3) · Bacteremia (2) · Cardiovascular Diseases (2) · Periodontal Attachment Loss (2) · Premature Birth (2)
Postgraduate Institute of Dental Sciences Rohtak (6) · Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre (5) · Meenakshi Ammal Dental College and Hospital (4) · University of Sao Paulo (4) · Alexandria University (3) · Belén Retamal-Valdes (3) · Cairo University (3) · Assiut University (2) · Ataturk University (2) · Inonu University (2) · Mansoura University (2) · Marmara University (2) · October 6 University (2) · Ondine Research Laboratories (2) · Tanta University (2)
United States (16) · India (14) · Egypt (13) · Turkey (Türkiye) (13) · Brazil (9) · Italy (4) · Spain (4) · Canada (3) · Germany (2) · Saudi Arabia (2) · Vietnam (2) · Austria (1) · Chile (1) · Colombia (1) · Ecuador (1)
Gaetano Isola (2) · Magda Feres, Professor (2) · Maha R. Taalab, PhD (2) · Ahmed Mortada Fikry, professor (1) · Aliaa Gamaleldin Aboulela, PhD (1) · Alpiste Illueca Francisco, Professor (1) · Andrea Vergara (1) · Anne D Haffajee, BDS (1) · Anne Haffajee, DDS (1) · Anthony DiAngelis, DMD (1) · Ariel Hirsch (1) · Armin Rashidi, MD, PhD (1) · Ayesha Ahmed (1) · Cansu Can Yasar, Dr. (1)
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R01DE014242 (1)