13 completed, 8 terminated. 21 Phase 2, 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 21 | Completed 13, Terminated 8 |
| Phase 1 | 5 | Completed 4, Terminated 1 |
Follow Reverse Transcriptase Polymerase Chain Reaction: new trials by email Literature Review of Reverse Transcriptase Polymerase Chain Reaction trials Research Report on Reverse Transcriptase Polymerase Chain Reaction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hsp90 Inhibitor STA-9090 in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy Hsp90 inhibitor STA-9090, laboratory biomarker analysis, polymerase chain reaction - Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer | Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 18 | 2011-01-01 | 2018-09-18 |
| Panobinostat and Letrozole in Treating Patients With Metastatic Breast Cancer letrozole, panobinostat, RNA analysis - Breast Cancer | Phase 1 / Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 28 | 2010-09-01 | 2017-06-27 |
| Low-Dose Azacitidine, Lenalidomide, and Low-Dose Dexamethasone in Relapsed or Refractory Multiple Myeloma azacitidine, lenalidomide, dexamethasone - Refractory Multiple Myeloma | Phase 1 / Phase 2 | Completed | Case Comprehensive Cancer Center | 45 | 2010-06-01 | 2020-11-16 |
| Panobinostat in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia panobinostat, gene expression analysis, reverse transcriptase-polymerase chain reaction - Leukemia | Phase 2 | Terminated | City of Hope Medical Center | 16 | 2008-04-01 | 2014-09-09 |
| Cetuximab, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Head and Neck Cancer That Cannot Be Removed By Surgery cetuximab, carboplatin, cisplatin - Head and Neck Cancer | Phase 2 | Terminated | European Organisation for Research and Treatment of Cancer - EORTC | 47 | 2008-02-01 | 2018-07-09 |
| Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma temozolomide, protein expression analysis, reverse transcriptase-polymerase chain reaction - Brain and Central Nervous System Tumors | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 47 | 2007-06-01 | 2016-02-29 |
| Combination Chemotherapy and Radiation Therapy With or Without Lapatinib in Treating Patients With Locally Advanced Cancer of the Larynx or Hypopharynx carboplatin, cisplatin, docetaxel - Head and Neck Cancer | Phase 1 / Phase 2 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 7 | 2007-05-01 | 2018-07-09 |
| Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery trastuzumab, cyclophosphamide, doxorubicin hydrochloride - Breast Cancer, Cardiac Toxicity | Phase 2 | Completed | Mayo Clinic | 122 | 2007-03-16 | 2022-08-05 |
| Oxaliplatin, Capecitabine, and Radiation Therapy in Patients Undergoing Surgery for Stage II, III, IV Esophageal Cancer capecitabine, oxaliplatin, gene expression analysis - Esophageal Cancer | Phase 2 | Completed | Roswell Park Cancer Institute | 41 | 2006-11-01 | 2013-11-25 |
| Everolimus in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Previous Therapy everolimus, antiangiogenesis therapy, biopsy - Colorectal Cancer | Phase 2 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 1 | 2006-10-01 | 2014-10-08 |
| Oxaliplatin and Pemetrexed Disodium in Treating Patients With Refractory Hormone-Resistant Prostate Cancer oxaliplatin, pemetrexed disodium, questionnaire administration - Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer | Phase 2 | Completed | University of Southern California | 47 | 2006-06-01 | 2014-03-10 |
| Paclitaxel, Cyclophosphamide & Doxorubicin, Autologous Dendritic Cells & Surgery in Stage II/III Breast Cancer (Women) therapeutic autologous dendritic cells, aromatase inhibition therapy, cyclophosphamide - Breast Cancer | Phase 2 | Completed | University of Nebraska | 17 | 2006-05-01 | 2023-09-29 |
| Nelfinavir Mesylate in Treating Patients With Recurrent, Metastatic, or Unresectable Liposarcoma nelfinavir mesylate, biopsy, laboratory biomarker analysis - Adult Liposarcoma, Recurrent Adult Soft Tissue Sarcoma | Phase 1 / Phase 2 | Terminated | City of Hope Medical Center | 29 | 2006-03-01 | 2015-04-01 |
| Celecoxib and Recombinant Interferon Alfa-2b in Metastatic Kidney Cancer Who Have Undergone Surgery celecoxib, recombinant interferon alfa-2b, polymerase chain reaction - Renal Cell Cancer, Stage IV Renal Cell Cancer | Phase 2 | Completed | Case Comprehensive Cancer Center | 17 | 2006-03-01 | 2012-08-07 |
| Vaccine Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia bcr-abl peptide vaccine, reverse transcriptase-polymerase chain reaction - Leukemia | Phase 2 | Terminated | OHSU Knight Cancer Institute | 4 | 2005-10-01 | 2011-09-02 |
| Cetuximab and Capecitabine in Treating Patients With Metastatic Colorectal Cancer That Failed Irinotecan Treatment cetuximab, capecitabine, gene expression analysis - Colorectal Cancer | Phase 2 | Terminated | City of Hope Medical Center | 13 | 2005-08-01 | 2014-08-28 |
| Bortezomib and Pemetrexed Disodium in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors bortezomib, pemetrexed disodium, gene expression analysis - Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 / Phase 2 | Completed | University of California, Davis | 27 | 2005-03-01 | 2018-10-31 |
| Combination Chemotherapy in Treating Patients With Previously Untreated Stage II or Stage III Esophageal Cancer That Can Be Removed By Surgery Docetaxel, Floxuridine, Leucovorin - Esophageal Cancer | Phase 2 | Completed | University of Miami | 29 | 2004-10-01 | 2017-02-07 |
| Biomarkers in Women Receiving Chemotherapy & Celecoxib for Stage II or Stage III Breast Cancer Removable by Surgery filgrastim, capecitabine, celecoxib - Breast Cancer | Phase 2 | Terminated | University of Nebraska | 3 | 2004-04-15 | 2023-09-13 |
| Interferon-gamma or Aldesleukin and Vaccine Therapy in Treating Patients With Multiple Myeloma aldesleukin, idiotype-pulsed autologous dendritic cell vaccine APC8020, recombinant interferon gamma - Multiple Myeloma and Plasma Cell Neoplasm | Phase 2 | Completed | Mayo Clinic | 15 | 2001-08-01 | 2011-05-16 |
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Breast Neoplasms (4) · Adenocarcinoma Of Esophagus (2) · Breast Neoplasms, Male (2) · Carcinoma, Non-Small-Cell Lung (2) · Colonic Neoplasms (2) · Colorectal Neoplasms (2) · Esophageal Neoplasms (2) · Head and Neck Neoplasms (2) · Leukemia (2) · Lung Neoplasms (2) · Multiple Myeloma (2) · Prostatic Neoplasms (2) · Rectal Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Astrocytoma (1)
City of Hope Medical Center (4) · Case Comprehensive Cancer Center (2) · European Organisation for Research and Treatment of Cancer - EORTC (2) · Mayo Clinic (2) · University of Nebraska (2) · Alliance for Clinical Trials in Oncology (1) · Barbara Ann Karmanos Cancer Institute (1) · Memorial Sloan Kettering Cancer Center (1) · OHSU Knight Cancer Institute (1) · Roswell Park Cancer Institute (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · University of California, Davis (1) · University of Miami (1) · University of Southern California (1)
United States (17) · Belgium (2)
Ahmad Awada, MD, PhD (1) · Angela Davies, MD (1) · Antonio Omuro, MD (1) · Bach Ardalan, MD (1) · Brian Rini (1) · Donald W. Northfeld, MD (1) · Edith A. Perez, MD (1) · Ehsan Malek, MD (1) · Elisabeth Heath (1) · Elizabeth C Reed, MD (1) · Elizabeth C. Reed, MD (1) · Frederic Reu (1) · Jacek Pinski (1) · James N. Ingle, MD (1) · Jan B. Vermorken, MD, PhD (1)
PMID 18090584, PMID 21258083, PMID 22989664, PMID 23243055, PMID 24099865, PMID 26774555, PMID 35135810
P30CA033572 (3), P30CA015083 (2), P30CA036727 (2), P30CA008748 (1)