6 recruiting, 6 terminated, 4 active not recruiting, 4 completed. 24 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 24 | Recruiting 6, Terminated 6, Active not recruiting 4, Completed 4, Withdrawn 2, Not yet recruiting 1, Suspended 1 |
| Phase 1 | 2 | Recruiting 1, Terminated 1 |
Follow Resection: new trials by email Literature Review of Resection trials Research Report on Resection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in Patients With Sarcoma, SarcoSIGHT Trial Electronic Health Record Review, Fluorescence Imaging, Fluorescence-Guided Surgery - High Grade Sarcoma, Sarcoma | Phase 2 | Recruiting | City of Hope Medical Center | 22 | 2026-08-14 | 2026-10-16 |
| Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment Zanidatamab, Resection, Patient Observation - Colon Carcinoma, Colorectal Carcinoma | Phase 2 | Recruiting | Emory University | 38 | 2026-04-07 | 2026-04-17 |
| Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery Biopsy Procedure, Biospecimen Collection, Cisplatin - Resectable Intrahepatic Cholangiocarcinoma | Phase 2 | Suspended | National Cancer Institute (NCI) | 27 | 2024-07-10 | 2026-09-04 |
| Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma Biopsy, Biospecimen Collection, Computed Tomography - Retroperitoneal Sarcoma | Phase 1 / Phase 2 | Recruiting | Northwestern University | 28 | 2024-04-02 | 2026-07-07 |
| Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial Stereotactic Ablative Radiotherapy, Resection, Microwave Ablation - Metastatic Colorectal Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8 | Phase 2 | Recruiting | Alliance for Clinical Trials in Oncology | 146 | 2023-10-09 | 2026-11-03 |
| Induction Chemotherapy and Tazemetostat for Locally Advanced SMARCB1-deficient Sinonasal Carcinoma Docetaxel, Cis Platinum, 5-FU - Sinonasal Carcinoma | Phase 2 | Not yet recruiting | Dr. Victor H.F. Lee | 30 | 2023-09-01 | 2023-02-28 |
| Impact of Total Intravenous Anesthesia Following Cancer Surgery, TIVACS Study Anesthesia Procedure, General Anesthesia Procedure, Resection - Pancreatic Adenocarcinoma | Phase 2 | Terminated | Ohio State University Comprehensive Cancer Center | 8 | 2023-06-02 | 2025-07-10 |
| Nivolumab and ADI-PEG 20 Before Surgery for the Treatment of Resectable Liver Cancer Nivolumab, Pegargiminase, Resection - Resectable Hepatocellular Carcinoma | Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2022-04-13 | 2023-02-16 | |
| Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer Carboplatin, Endoscopic Biopsy, External Beam Radiation Therapy - Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 2 | Active not recruiting | City of Hope Medical Center | 3 | 2022-01-25 | 2026-06-23 |
| NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer Capecitabine, Fluorouracil, Irinotecan Hydrochloride - Pancreatic Adenocarcinoma, Stage 0 Pancreatic Cancer American Joint Committee on Cancer v8 | Phase 2 | Active not recruiting | OHSU Knight Cancer Institute | 42 | 2021-05-27 | 2026-01-14 |
| Hypofractionated Radiotherapy Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas Ultra-Hypo-fractionation Radiotherapy, Resection, Questionnaire Administration - Soft Tissue Sarcomas | Phase 2 | Recruiting | Vanderbilt-Ingram Cancer Center | 40 | 2021-03-02 | 2025-03-28 |
| Radiation Therapy Before Surgery for Localized, Resectable Soft Tissue Sarcoma of the Extremity and Superficial Trunk Hypofractionated Radiation Therapy, Quality-of-Life Assessment, Questionnaire Administration - Resectable Soft Tissue Sarcoma, Stage I Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Phase 2 | Active not recruiting | Mayo Clinic | 120 | 2020-11-30 | 2026-02-04 |
| A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC) Alectinib, Entrectinib, Vemurafenib - Non-small Cell Lung Cancer | Phase 2 | Recruiting | Genentech, Inc. | 99 | 2020-11-06 | 2026-10-13 |
| A PD-1 Checkpoint Inhibitor (Cemiplimab) for High-Risk Localized, Locally Recurrent, or Regionally Advanced Skin Cancer Cemiplimab, Resection - Recurrent Skin Squamous Cell Carcinoma, Resectable Skin Squamous Cell Carcinoma | Phase 2 | Active not recruiting | University of Southern California | 35 | 2020-06-17 | 2026-06-01 |
| Biomarker Correlates of Hypoxia in Metastatic Melanoma Pimonidazole hydrochloride (Hypoxyprobe™-1), Optional 18F-FMISO PET scan (18F-fluoromisonidazole), Surgical Resection of Melanoma Metastases - Melanoma, Skin Cancer | Phase 2 | Withdrawn | H. Lee Moffitt Cancer Center and Research Institute | 2014-10-01 | 2016-05-09 | |
| Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer CRLX101, Capecitabine, Radiotherapy - Rectal Cancer | Phase 1 / Phase 2 | Terminated | UNC Lineberger Comprehensive Cancer Center | 32 | 2013-12-01 | 2020-11-03 |
| CHFR Methylation Status Esophageal Cancer Study Paclitaxel, Cisplatin, Oxaliplatin - Esophageal Cancer | Phase 2 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 31 | 2011-06-01 | 2019-01-25 |
| S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer cetuximab, capecitabine, oxaliplatin - Colorectal Cancer | Phase 2 | Completed | SWOG Cancer Research Network | 83 | 2009-02-01 | 2018-05-18 |
| Preoperative Chemotherapy (Gemcitabine and Erlotinib) With or Without Radiation Therapy Gemcitabine, Radiation Therapy, Erlotinib - Pancreatic Cancer | Phase 2 | Terminated | M.D. Anderson Cancer Center | 5 | 2008-09-01 | 2016-05-19 |
| Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer capecitabine, oxaliplatin, resection - Colorectal Cancer | Phase 2 | Completed | Radiation Therapy Oncology Group | 79 | 2008-04-01 | 2018-09-25 |
Showing 20 of 24. Sign in to see all of them.
Carcinoma, Non-Small-Cell Lung (5) · Colorectal Neoplasms (5) · Lung Neoplasms (4) · Rectal Neoplasms (4) · Sarcoma (2) · Skin Neoplasms (2) · Adenocarcinoma Of Esophagus (1) · Adenocarcinoma of Lung (1) · Colonic Neoplasms (1) · Esophageal Neoplasms (1) · Esophageal Squamous Cell Carcinoma (1) · Melanoma (1) · Pancreatic Neoplasms (1)
City of Hope Medical Center (2) · M.D. Anderson Cancer Center (2) · Radiation Therapy Oncology Group (2) · Alliance for Clinical Trials in Oncology (1) · Dr. Victor H.F. Lee (1) · Emory University (1) · Genentech, Inc. (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Masonic Cancer Center, University of Minnesota (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · National Cancer Institute (NCI) (1) · Northwestern University (1) · OHSU Knight Cancer Institute (1) · Ohio State University Comprehensive Cancer Center (1)
United States (22) · Canada (2)
Adam C. Berger, MD (1) · Andrew Wang, MD (1) · Arkadiusz Dudek, MD (1) · Aslam Ejaz, MD (1) · Charles D Lopez (1) · Cynthia G. Leichman, MD (1) · Eric Shinohara, MD (1) · Gino K In, MD (1) · Hop S Tran Cao (1) · Jason B. Fleming, MD (1) · Johanna Bendell, MD (1) · Jonathan Zager, M.D. (1) · Michael C. Garofalo, MD (1) · Mohan Suntharalingam, MD (1)
PMID 22543206, PMID 27784746, PMID 30858085, PMID 36652155, PMID 38350888, PMID 40389098
P30CA033572 (2), P30CA014089 (1), P30CA060553 (1), P30CA138292 (1), R33CA127055 (1), U10CA032102 (1), UM1CA186688 (1)