5 completed, 3 active not recruiting, 2 recruiting, 2 unknown. 14 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 14 | Completed 5, Active not recruiting 3, Recruiting 2, Unknown 2, Terminated 1, Withdrawn 1 |
Follow Probiotics: new trials by email Literature Review of Probiotics trials Research Report on Probiotics
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy Biospecimen Collection, Placebo Administration, Probiotic - Advanced Ovarian Carcinoma, Recurrent Ovarian Carcinoma | Early Phase 1 | Recruiting | Ohio State University Comprehensive Cancer Center | 161 | 2026-03-06 | 2026-08-17 |
| Microbiome and Clinical Response to Probiotics and Methotrexate in Early Psoriasis: a Pilot Study Probiotics and methotrexate, Methotrexate - Psoriasis (PsO) | Early Phase 1 | Recruiting | Alexandria University | 24 | 2025-08-01 | 2025-09-11 |
| L. Acidophilus (Strain TW01) on Gut Health, Body Composition, and Inflammation Placebo, Probiotic - Overweight (BMI > 25), Obese, Otherwise Healthy Volunteers | Early Phase 1 | Active not recruiting | University of Connecticut | 12 | 2025-07-01 | 2026-08-13 |
| Metagenomic & Metabolomic Study: Bifidobacterium Probiotic Effects on Gut Microbiota & SCFA in Preterm NICU Infants Probiotics - Prematurity, Low Birth Weight Neonates | Early Phase 1 | Active not recruiting | Hasanuddin University | 72 | 2024-09-02 | 2025-10-08 |
| The Gut, Liver And Metabolome in Human Immunodeficiency Virus and Non Alcoholic Fatty Liver Disease Prebiotic, Probiotic - HIV, Non-Alcoholic Fatty Liver Disease | Early Phase 1 | Active not recruiting | Vanderbilt University Medical Center | 63 | 2024-04-18 | 2026-04-14 |
| Gut Health and the Effect on Substance and Alcohol Cravings probiotic and pickle - Craving | Early Phase 1 | Unknown | City Rescue Mission Medical Clinic | 30 | 2023-09-01 | 2023-09-07 |
| Multistrain Probiotics Against Bacterial Vaginosis OMNi-BiOTiC® FLORA plus+, antibiotic - Bacterial Vaginosis (BV) | Early Phase 1 | Terminated | Institut AllergoSan Pharma GmbH | 56 | 2022-12-12 | 2025-03-21 |
| Oral Vancomycin Versus Probiotics Versus Placebo for Prevention of Clostridium Difficile Infection in Colonized Patients Vancomycin, Culturelle, Vancomycin Placebo - Clostridium Difficile Colonization, Clostridium Difficile Diarrhea | Early Phase 1 | Withdrawn | Hamilton Health Sciences Corporation | 2022-09-01 | 2025-02-20 | |
| Effects of Probiotics on the Gut Microbiome and Immune System in Operable Stage I-III Breast or Lung Cancer Biopsy, Biospecimen Collection, Probiotic - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Early Phase 1 | Completed | Mayo Clinic | 6 | 2021-07-01 | 2023-04-21 |
| Prevention of Acute Exacerbation in Subjects With COPD by Bacterial Decolonization in Lower Respiratory Tract oral probiotics, aerosol inhaled amikacin, combined vaccination - Chronic Obstructive Pulmonary Disease (COPD) | Early Phase 1 | Completed | Shanghai Zhongshan Hospital | 144 | 2018-12-01 | 2022-06-23 |
| Impact of Probiotics on Oral Microbiota in Older Adults With Dysphagia VSL#3 - Dysphagia | Early Phase 1 | Completed | University of Wisconsin, Madison | 9 | 2018-08-27 | 2024-05-16 |
| the Microbiota Are Associated With Iodine-131 Therapy and Hypothyroidism Probiotic - Microbiota | Early Phase 1 | Unknown | First Affiliated Hospital of Harbin Medical University | 30 | 2018-05-01 | 2018-07-16 |
| Probiotic Supplementation to Improve the GUT Microbiota of Very Low Birth Weight Preterm, a Pilot Study Probiotic - Other Preterm Infants, NEC | Early Phase 1 | Completed | Hospital Universitario La Paz | 5 | 2012-12-01 | 2014-07-17 |
| A Trial on Conservative Treatment for Infants' Hirschsprung Disease surgery treatment, anal dilation, colonic lavage - Hirschsprung Disease | Early Phase 1 | Completed | Tongji Hospital | 48 | 2009-10-01 | 2013-11-15 |
Deglutition Disorders (1) · Hirschsprung Disease (1) · Lung Neoplasms (1) · Non-alcoholic Fatty Liver Disease (1) · Obesity (1) · Ovarian Neoplasms (1) · Overweight (1) · Premature Birth (1) · Psoriasis (1) · Pulmonary Disease, Chronic Obstructive (1) · Thyroid Neoplasms (1) · Vaginosis, Bacterial (1)
Alexandria University (1) · City Rescue Mission Medical Clinic (1) · First Affiliated Hospital of Harbin Medical University (1) · Hamilton Health Sciences Corporation (1) · Hasanuddin University (1) · Hospital Universitario La Paz (1) · Institut AllergoSan Pharma GmbH (1) · Mayo Clinic (1) · Ohio State University Comprehensive Cancer Center (1) · Shanghai Zhongshan Hospital (1) · Tongji Hospital (1) · University of Connecticut (1) · University of Wisconsin, Madison (1) · Vanderbilt University Medical Center (1)
United States (5) · China (2) · Austria (1) · Canada (1) · Egypt (1) · Indonesia (1) · Spain (1)
Adhariana H Kaddas, Neonatologist (1) · Anna McCarthy, MD MPH (1) · Doris Maria Gruber, Univ. Prof. Dr. (1) · Ezzeldin A. Saleh, PhD (1) · Gamaleldin A. Elsawaf, PhD (1) · Jing Zhang, MD, PhD (1) · Laura Chambers, DO (1) · Miguel Saenz de Pipaon, PhD. MD. (1) · Mohamed A. Alqasem, MSc (1) · Saranya Chumsri (1) · Yunwei Wei (1)
PMID 22224779, PMID 28588585, PMID 30793796, PMID 31453631, PMID 33926088, PMID 34769005, PMID 35304068, PMID 35350100, PMID 37908308, PMID 37953417, PMID 38249987