6 completed, 3 not yet recruiting, 2 recruiting, 2 withdrawn. 15 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Completed 6, Not yet recruiting 3, Recruiting 2, Withdrawn 2, Active not recruiting 1, Unknown 1 |
| Phase 3 | 3 | Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow placebo drug: new trials by email Literature Review of placebo drug trials Research Report on placebo drug
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Choline and Iron Deficiency choline bitartrate, placebo drug - Pediatric Iron Deficiency, Anemia | Phase 2 / Phase 3 | Recruiting | University of Minnesota | 300 | 2025-08-11 | 2026-08-05 |
| Effect of Sinbiotic With Multispecies Probiotics on Liver Parameters Liver Enzymes, Ultrasound, Elastography and Adipokines in Same Cases) in Patients With Metabolic Associated Steatotic Liver Disease. The test product is a ready-to-use sinbiotic preparation of multispecies probiotics, ca-butyrate and FOS, Placebo Drug - MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis), Diabetes Mellitus | Phase 2 | Not yet recruiting | Eva Cubric | 114 | 2025-07-01 | 2025-06-18 |
| Phase IIa Trial of Oral SSS17 for Post-Arthroplasty Anemia SSS17 Capsule (6 Dose Levels), Placebo Drug - Postoperative Anemia, Arthroplasty, Replacement, Hip | Phase 2 | Not yet recruiting | Shenyang Sunshine Pharmaceutical Co., LTD. | 90 | 2025-07-01 | 2025-06-11 |
| Initial Pilot Study to Evaluate the Safety and Temporary Symptom Improvement Efficacy of CKD-981 CKD-981(1), CKD-981(2), Sham device - Knee Osteoarthritis | Phase 2 | Completed | Chong Kun Dang Pharmaceutical | 100 | 2025-04-28 | 2026-04-13 |
| Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease LHP588, Placebo Drug - Alzheimer Disease, Alzheimer Disease Due to P. Gingivalis | Phase 2 | Recruiting | Lighthouse Pharmaceuticals, Inc. | 300 | 2025-02-17 | 2026-10-07 |
| Evaluating Efficacy and Safety of Oral Melatonin in Acute Central Serous Chorioretinopathy melatonin 3mg, Placebo Drug - Central Serous Chorioretinopathy, Melatonin | Phase 2 / Phase 3 | Not yet recruiting | Mohsen Pourazizi | 48 | 2025-02-01 | 2025-02-05 |
| Efficacy of Locally Delivered Rosemary Extract Gel in Management of Periodontitis Herbal therapy, Placebo Drug - Periodontitis (Stage 3), Periodontal Pocket | Phase 2 | Completed | Ain Shams University | 48 | 2024-10-20 | 2026-04-13 |
| The Therapeutic Effects of Bu Shen Yi Jing Pill on Semen Quality in Sub Fertile Males: a Randomized Controlled Trial Bu Shen Yi Jing Pill, Placebo Drug - Male Infertility, Infertility | Phase 2 | Active not recruiting | KK Women's and Children's Hospital | 59 | 2022-01-07 | 2024-10-10 |
| Trial Comparing Preoperative Dienogest Therapy Followed by Surgery vs. Upfront Surgery to Save Ovarian Reserve in Young Women With Ovarian Endometrioma Dienogest, Placebo drug, Surgery - Ovarian Reserve, Endometriosis | Phase 2 | Withdrawn | Seoul National University Hospital | 2017-10-01 | 2017-10-31 | |
| Use of Sildenafil Citrate in Management of Mild Pre-eclampsia Sildenafil 20 MG, Placebo Oral Tablet - Pre-Eclampsia; Mild | Phase 2 / Phase 3 | Unknown | Assiut University | 80 | 2016-09-15 | 2017-08-28 |
| A Randomized, Controlled Trial of Intranasal Oxytocin as an Adjunct to Behavioral Therapy for Autism Spectrum Disorder Oxytocin, Social Skills focused CBT, Stress management/relaxation training - Autism Spectrum Disorders | Phase 2 | Completed | Massachusetts General Hospital | 92 | 2014-04-01 | 2020-01-27 |
| Apixaban for the Prevention of Venous Thromboembolism in Cancer Patients Apixaban, Placebo drug - Venous Thromboembolism, Cancer | Phase 2 | Completed | Ottawa Hospital Research Institute | 575 | 2014-03-24 | 2018-11-20 |
| HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone Acyline, placebo hCG (no active ingredient), hCG (human chorionic gonadotropin) - Healthy Males | Phase 1 / Phase 2 | Completed | University of Washington | 59 | 2009-03-01 | 2016-01-11 |
| Phase II Study of Heart Polypill Safety and Efficacy in Primary Prevention of Cardiovascular Disease Polypill, Placebo drug - Cardiovascular Disease, Hypertension | Phase 2 | Completed | Tehran University of Medical Sciences | 475 | 2006-11-01 | 2009-10-02 |
| Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-3 - 6 Test Drug, Placebo Drug - Heroin Dependence, Opioid-Related Disorders | Phase 2 | Withdrawn | University of Colorado, Denver | 2002-12-01 | 2017-05-04 |
Diabetes Mellitus (2) · Hyperlipidemias (2) · Hypertension (2) · Alzheimer Disease (1) · Anemia (1) · Autism Spectrum Disorder (1) · Cardiovascular Diseases (1) · Central Serous Chorioretinopathy (1) · Endometriosis (1) · Heart Diseases (1) · Heroin Dependence (1) · Infertility (1) · Infertility, Male (1) · Iron Deficiencies (1) · Lymphoma, Follicular (1)
Ain Shams University (1) · Assiut University (1) · Chong Kun Dang Pharmaceutical (1) · Eva Cubric (1) · KK Women's and Children's Hospital (1) · Lighthouse Pharmaceuticals, Inc. (1) · Massachusetts General Hospital (1) · Mohsen Pourazizi (1) · Ottawa Hospital Research Institute (1) · Seoul National University Hospital (1) · Shenyang Sunshine Pharmaceutical Co., LTD. (1) · Tehran University of Medical Sciences (1) · University of Colorado, Denver (1) · University of Minnesota (1) · University of Washington (1)
United States (5) · Egypt (2) · South Korea (2) · Canada (1) · China (1) · Croatia (1) · Iran (1) · Singapore (1)
Akram Pourshams, PhD (1) · Aude Henin, PhD (1) · Fady Abdallah (1) · Fatemeh Malekzadeh, M.D. (1) · Hasan Kamel (1) · Hisham Abou-Taleb (1) · John Gabrieli, PhD (1) · Kar K Cheng, PhD (1) · Leslie Amass, Ph.D. (1) · Mansoor Rastegarpanah, Ph.D. (1) · Marc Carrier, MD (1) · Marko Skelin, ass.prof.dr.sc, mag.pharm. (1) · Mohsen Pourazizi (1) · Phil Wells, MD (1)
PMID 15507947, PMID 15713717, PMID 20484472, PMID 21374750, PMID 23040523, PMID 23798922, PMID 27400005, PMID 29557414, PMID 30511879, PMID 33337539, PMID 33857789, PMID 34622445, PMID 35124234, PMID 35660801, PMID 37811711, PMID 41257751, PMID 7504210, PMID 8623789, PMID 9819872
R01DA011160 (1), U54HD012629 (1)