17 completed, 7 not yet recruiting, 5 recruiting, 4 unknown. 15 Phase 2, 11 Phase 4, 6 Not applicable, 5 Phase 3, 4 Phase 1.
Follow Placebo Drug: new trials by email Literature Review of Placebo Drug trials Research Report on Placebo Drug
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Statins to Prevent Cancer Associated Blood Clots Rosuvastatin, Placebo Drug - Venous Thromboembolism, Cancer | Phase 4 | Recruiting | Brigham and Women's Hospital | 4000 | 2026-06-11 | 2026-09-16 |
| Clinical Study on Guben Kechuan Granules Promoting Disease Recovery by Regulating Immune-Inflammatory Dysregulation in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease During the Peri-Discharge Period Guben Kechuan Granules group, Placebo Drug - Chronic Obstructive Pulmonary Disease (COPD) | Not applicable | Not yet recruiting | Cuiling Feng | 126 | 2026-03-15 | 2026-03-06 |
| Efficacy and Safety of Stapokibart for Primary Cutaneous Amyloidosis Stapokibart, Placebo drug - Primary Cutaneous Amyloidosis | Not applicable | Not yet recruiting | First Affiliated Hospital of Chongqing Medical University | 40 | 2025-09-15 | 2025-08-27 |
| Choline and Iron Deficiency choline bitartrate, placebo drug - Pediatric Iron Deficiency, Anemia | Phase 2 / Phase 3 | Recruiting | University of Minnesota | 300 | 2025-08-11 | 2026-08-05 |
| Effect of Sinbiotic With Multispecies Probiotics on Liver Parameters Liver Enzymes, Ultrasound, Elastography and Adipokines in Same Cases) in Patients With Metabolic Associated Steatotic Liver Disease. The test product is a ready-to-use sinbiotic preparation of multispecies probiotics, ca-butyrate and FOS, Placebo Drug - MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis), Diabetes Mellitus | Phase 2 | Not yet recruiting | Eva Cubric | 114 | 2025-07-01 | 2025-06-18 |
| Phase IIa Trial of Oral SSS17 for Post-Arthroplasty Anemia SSS17 Capsule (6 Dose Levels), Placebo Drug - Postoperative Anemia, Arthroplasty, Replacement, Hip | Phase 2 | Not yet recruiting | Shenyang Sunshine Pharmaceutical Co., LTD. | 90 | 2025-07-01 | 2025-06-11 |
| Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis Decartes-08, Placebo Drug - Myasthaenia Gravis | Phase 3 | Active not recruiting | Cartesian Therapeutics | 128 | 2025-05-06 | 2026-09-01 |
| Initial Pilot Study to Evaluate the Safety and Temporary Symptom Improvement Efficacy of CKD-981 CKD-981(1), CKD-981(2), Sham device - Knee Osteoarthritis | Phase 2 | Completed | Chong Kun Dang Pharmaceutical | 100 | 2025-04-28 | 2026-04-13 |
| Clinical Evaluation of Aromatic Wentong in the Treatment of Coronary Microvascular Disease Kuangxiong Aerosol, Placebo Drug - Coronary Microvascular Disease | Phase 4 | Not yet recruiting | China-Japan Friendship Hospital | 528 | 2025-04-01 | 2025-04-11 |
| Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease LHP588, Placebo Drug - Alzheimer Disease, Alzheimer Disease Due to P. Gingivalis | Phase 2 | Recruiting | Lighthouse Pharmaceuticals, Inc. | 300 | 2025-02-17 | 2026-10-07 |
| Efficacy and Safety of Oral Probiotics on Ocular Symptoms and Gut Microbiome of Children with Vernal Keratoconjunctivitis Probiotic, Placebo Drug - Probiotic, Ocular Surface Disease | Phase 1 | Not yet recruiting | Mohsen Pourazizi | 32 | 2025-02-01 | 2025-01-27 |
| Evaluating Efficacy and Safety of Oral Melatonin in Acute Central Serous Chorioretinopathy melatonin 3mg, Placebo Drug - Central Serous Chorioretinopathy, Melatonin | Phase 2 / Phase 3 | Not yet recruiting | Mohsen Pourazizi | 48 | 2025-02-01 | 2025-02-05 |
| Magnesium Sulfate and Postoperative Hypercoagulability in Laparoscopic Gynecological Surgeries Magnesium sulphate, Placebo Drug - Magnesium Sulfate, Thromboelastometry | Not applicable | Recruiting | Marianna Mavromati | 60 | 2024-12-01 | 2024-12-05 |
| Efficacy of Locally Delivered Rosemary Extract Gel in Management of Periodontitis Herbal therapy, Placebo Drug - Periodontitis (Stage 3), Periodontal Pocket | Phase 2 | Completed | Ain Shams University | 48 | 2024-10-20 | 2026-04-13 |
| Efficacy Of Sodium Glucose Transporter Inhibitor (SGLT2I) In Adult Patients With Congenital Heart Disease Empagliflozin 10 MG, Placebo - Adult Congenital Heart Disease, Heart Failure | Phase 4 | Active not recruiting | Anita Saraf | 40 | 2024-09-17 | 2026-09-17 |
| Capsule Microbiota Transplant Therapy for Hidradenitis Suppurativa Fecal Microbiota - lyophilized, Placebo drug - Hidradenitis Suppurativa | Early Phase 1 | Recruiting | University of Minnesota | 16 | 2023-12-27 | 2026-09-03 |
| Treatment of Tinnitus With Olanzapine Olanzapine 5 Mg ORAL TABLET, Placebo Drug - Tinnitus, Tinnitus, Subjective | Phase 1 | Completed | University of Sao Paulo | 50 | 2023-10-01 | 2026-09-15 |
| Effect of Atorvastatin as a Renal Protection in Patients With Systemic Inflammatory Response Syndrome Using Renal Arterial Resistive Index Atorvastatin 40 Mg Oral Tablet, placebo drug - Renal Protection | Phase 1 | Unknown | Minia University | 106 | 2023-05-30 | 2023-07-14 |
| Effects of Usage of Simvastatin in Mild to Moderate Traumatic Brain Injury (TBI) Patients. Could it Make a Difference? Simvastatin, Placebo drug - Traumatic Brain Injury | Not applicable | Unknown | Assiut University | 60 | 2022-10-01 | 2022-10-10 |
| Effects of 4-AP on Functional SCI Recovery Dalfampridine, Placebo drug, STDP stimulation - Spinal Cord Injury | Early Phase 1 | Completed | Shirley Ryan AbilityLab | 26 | 2022-06-30 | 2026-06-03 |
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Hyperlipidemias (3) · Diabetes Mellitus (2) · Diabetes Mellitus, Type 2 (2) · Heart Failure (2) · Hypertension (2) · Neoplasms (2) · Spinal Cord Injuries (2) · Venous Thromboembolism (2) · Agnosia (1) · Alzheimer Disease (1) · Amyloidosis, Primary Cutaneous (1) · Anemia (1) · Aortic Valve Stenosis (1) · Autism Spectrum Disorder (1) · Brain Injuries, Traumatic (1)
Assiut University (2) · Mohsen Pourazizi (2) · Seoul National University Hospital (2) · Shirley Ryan AbilityLab (2) · University of Minnesota (2) · Ain Shams University (1) · Anita Saraf (1) · Brigham and Women's Hospital (1) · Cartesian Therapeutics (1) · China-Japan Friendship Hospital (1) · Chong Kun Dang Pharmaceutical (1) · Columbia University (1) · Cuiling Feng (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Eva Cubric (1)
United States (14) · South Korea (4) · China (3) · Egypt (3) · Canada (2) · Iran (2) · Brazil (1) · Croatia (1) · Denmark (1) · France (1) · Greece (1) · Italy (1) · Poland (1) · Serbia (1) · Singapore (1)
Mohsen Pourazizi (2) · Akram Pourshams, PhD (1) · Anita Saraf, MD, PhD (1) · Aude Henin, PhD (1) · Christine Rohde, MD (1) · Emad Zarief Kamel, MD (1) · Fady Abdallah (1) · Fatemeh Malekzadeh, M.D. (1) · Hasan Kamel (1) · Hisham Abou-Taleb (1) · Jin S. Yeom, M.D. (1) · John Gabrieli, PhD (1) · Kar K Cheng, PhD (1) · Kassiani Theodoraki, Professor (1)
PMID 15507947, PMID 15713717, PMID 20484472, PMID 21374750, PMID 23040523, PMID 23798922, PMID 25482466, PMID 27400005, PMID 29557414, PMID 30511879, PMID 33337539, PMID 33857789, PMID 34622445, PMID 35124234, PMID 35235659, PMID 35660801, PMID 37811711, PMID 40347940, PMID 41257751, PMID 41559698, PMID 7504210, PMID 8623789, PMID 9819872
R01DA011160 (1), R01DK107680 (1), R35NS122336 (1), U54HD012629 (1), UG3HL176627 (1)