23 completed, 4 active not recruiting, 4 recruiting, 4 unknown. 44 Phase 3, 10 Phase 2.
Follow Placebo control: new trials by email Literature Review of Placebo control trials Research Report on Placebo control
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of HSK39004 Inhalation Suspension in Patients With COPD HSK39004 Inhalation Suspension, Placebo control - COPD (Chronic Obstructive Pulmonary Disease) | Phase 3 | Not yet recruiting | Haisco Pharmaceutical Group Co., Ltd. | 387 | 2026-07-11 | 2026-06-22 |
| Confirmatory Study of Govorestat in CMT-SORD Govorestat, Placebo Control - Charcot-Marie-Tooth Disease With Sorbitol Dehydrogenase Deficiency (CMT-SORD) | Phase 3 | Withdrawn | Applied Therapeutics, Inc. | 2026-05-01 | 2026-05-29 | |
| To Evaluate the Efficacy, Safety, and Tolerability of Dronabinol Oral Solution for Agitation in Patients With Alzheimer's Disease Dronabinol Oral Solution, Placebo Control - Agitation in Dementia | Phase 2 / Phase 3 | Not yet recruiting | Benuvia Therapeutics Inc. | 140 | 2026-05-01 | 2026-02-25 |
| Adaptive Platform Trial of Treatments for Respiratory Infections in Community Settings (TreatResp) Baloxavir, Placebo Control - Influenza A, Influenza B | Phase 3 | Recruiting | Unity Health Toronto | 264 | 2026-04-29 | 2026-08-18 |
| Thymosin-α1 for Recurrent Implantation Failure Thymosin Alpha1, Placebo Control - Recurrent Implantation Faliure | Phase 2 / Phase 3 | Recruiting | Fakih IVF Fertility Center | 136 | 2026-02-11 | 2026-10-15 |
| Non-invasive Ventilation and Dexmedetomidine in Critically Ill Adults Dexmedetomidine, Placebo Control - Non-Invasive Ventilation | Phase 3 | Recruiting | St. Joseph's Healthcare Hamilton | 846 | 2025-07-29 | 2025-09-10 |
| Evaluation of Early Administration of Levetiracetam in the Prevention and Treatment Encephalopathy in Septic Shock: Randomized, Double-blind, Placebo-controlled Trial Levetiracetam IV, Placebo control - Septic Shock | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 280 | 2025-03-15 | 2025-03-12 |
| Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML Quizartinib, Placebo, Chemotherapy - Leukemia | Phase 3 | Active not recruiting | Daiichi Sankyo | 700 | 2024-11-19 | 2026-07-02 |
| Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm Endothelin Receptor Antagonist, Placebo control - Coronary Spasm | Phase 2 / Phase 3 | Enrolling by invitation | Radboud University Medical Center | 100 | 2024-11-11 | 2024-11-18 |
| VTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy Rivaroxaban 10 MG, Placebo control - Venous Thromboembolism, Urologic Cancer | Phase 2 / Phase 3 | Recruiting | Ottawa Hospital Research Institute | 120 | 2024-11-04 | 2025-07-10 |
| SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes Empagliflozin, Placebo Control - Cystic Fibrosis-related Diabetes, Cystic Fibrosis | Phase 2 / Phase 3 | Active not recruiting | University of Minnesota | 8 | 2024-01-08 | 2026-09-21 |
| Dexamethasone Treatment for OSA in Children Dexamethasone, Placebo Control - Obstructive Sleep Apnea | Phase 3 | Completed | The Hospital for Sick Children | 10 | 2022-10-26 | 2026-05-12 |
| Study to Determine the Efficacy and Safety of TG-C in Subjects With Kellgren/Lawrence Grade 2 or 3 OA of the Knee TG-C, Placebo Control - Degenerative Osteoarthritis | Phase 3 | Completed | Kolon TissueGene, Inc. | 531 | 2021-12-09 | 2026-08-20 |
| A Global Phase III Clinical Trial of Recombinant COVID- 19 Vaccine (Sf9 Cells) Recombinant COVID-19 vaccine (Sf9 cells), Placebo control - COVID-19 | Phase 3 | Completed | WestVac Biopharma Co., Ltd. | 39663 | 2021-06-15 | 2025-03-26 |
| A Phase 2b/3a Study to Evaluate the Efficacy and Safety of JointStem in Patients Diagnosed as Knee Osteoarthritis JointStem, Placebo Control - Osteoarthritis, Knee | Phase 2 / Phase 3 | Active not recruiting | Nature Cell Co. Ltd. | 173 | 2021-05-26 | 2026-08-03 |
| Garcinia Mangostana L Rind and Solanum Lycopersicum Fructus Trial to Prevent Exercise-induced Oxidative Stress Garcinia-mangostana-L-rind and Solanum-Lycopersicum-Fructus mixture-extract, Placebo Control - Exertion; Excess, Oxidative Stress | Phase 2 / Phase 3 | Unknown | Universitas Negeri Semarang | 30 | 2020-07-15 | 2019-07-30 |
| A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee TG-C, Placebo Control - Degenerative Osteoarthritis | Phase 3 | Active not recruiting | Kolon TissueGene, Inc. | 535 | 2018-10-30 | 2026-08-20 |
| Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility) Bempedoic acid, Ezetimibe, Placebo - Hypercholesterolemia, Atherosclerosis | Phase 3 | Completed | Esperion Therapeutics, Inc. | 269 | 2016-11-29 | 2020-05-11 |
| Clinical Study of Recombinant Anti-HER2 Humanized Monoclonal Antibody (GB221) for Injection GB221, Placebo control - HER-2-positive Advanced Breast Cancer | Phase 3 | Unknown | Genor Biopharma Co., Ltd. | 336 | 2016-11-24 | 2019-11-15 |
| Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk bempedoic acid, placebo - Hypercholesterolemia, Atherosclerotic Cardiovascular Disease | Phase 3 | Completed | Esperion Therapeutics, Inc. | 779 | 2016-11-18 | 2020-04-27 |
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Atherosclerosis (3) · Epilepsy (3) · Hypercholesterolemia (3) · Hypersensitivity (3) · Papillomavirus Infections (3) · Uterine Cervical Neoplasms (3) · Alzheimer Disease (2) · COVID-19 (2) · Cystic Fibrosis (2) · Epilepsies, Myoclonic (2) · Hyperlipidemias (2) · Hyperlipoproteinemia Type II (2) · Joint Diseases (2) · Leukemia (2) · Leukemia, Myeloid, Acute (2)
GlaxoSmithKline (4) · Artu Biologicals (3) · Esperion Therapeutics, Inc. (3) · Jazz Pharmaceuticals (3) · Daiichi Sankyo (2) · JANSSEN Alzheimer Immunotherapy Research & Development, LLC (2) · Kolon TissueGene, Inc. (2) · Lindner Center of HOPE (2) · Applied Therapeutics, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Benuvia Therapeutics Inc. (1) · Fakih IVF Fertility Center (1) · Genor Biopharma Co., Ltd. (1) · Haisco Pharmaceutical Group Co., Ltd. (1) · London School of Hygiene and Tropical Medicine (1)
United States (25) · Canada (11) · Australia (8) · Germany (8) · Netherlands (8) · United Kingdom (8) · France (7) · China (6) · Poland (6) · Spain (6) · Czechia (5) · Hungary (5) · Singapore (5) · Belgium (4) · Bulgaria (4)
Ron Haberman, MD (3) · Moon Jong Noh, PhD (2) · Andrew Pinto, MD (1) · Daniel Qi, M.D. (1) · Dyonne van Duren, MD, PhD (1) · Folkert R Roossien (1) · Folkert Roossien (1) · Indra Narang, MD (1) · Iveta Kozlovska, MD, PhD (1) · Joanne Fraser, PhD (1) · Joseph Neimat, M.D. (1) · Kent Allenby, MD (1) · Kimberley Lewis, MD (1)
PMID 32609313, PMID 35916348, PMID 24450891, PMID 26208959, PMID 28269765, PMID 29854934, PMID 29854935, PMID 30412493, PMID 31824976, PMID 34265088, PMID 41276263, PMID 20131255, PMID 23113480, PMID 23200183, PMID 23967083, PMID 25424785, PMID 26685704, PMID 29768152, PMID 29859851, PMID 29910030, PMID 30922146, PMID 30955420, PMID 31273942, PMID 31305011, PMID 32119035, PMID 32780946, PMID 33180670, PMID 33198657, PMID 33229973, PMID 33797076, PMID 33825230, PMID 34870327, PMID 34939897, PMID 35662406, PMID 37052803, PMID 37116523, PMID 40079105, PMID 40274007, PMID 40452051, PMID 40775196, PMID 41052406, PMID 41791832, PMID 41949390, PMID 42434847
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