165 completed, 35 recruiting, 29 unknown, 22 not yet recruiting. 116 Not applicable, 66 Phase 2, 50 Phase 1, 44 Phase 3, 24 Phase 4.
Follow Placebo control: new trials by email Literature Review of Placebo control trials Research Report on Placebo control
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gut Microbiome Changes During Abemaciclib Therapy in Breast Cancer Resistant Potato Starch, Placebo control - Breast Cancer, HER-2 Positive Breast Cancer | Not applicable | Not yet recruiting | University of Vermont Medical Center | 12 | 2027-10-01 | 2026-02-12 |
| A Study to Determine the Safety and Efficacy of TG-C in Subjects With Symptomatic Early Hip Osteoarthritis TG-C, Placebo Control - Degenerative Osteoarthritis | Phase 2 | Not yet recruiting | Kolon TissueGene, Inc. | 255 | 2027-10-01 | 2026-08-20 |
| Study of CU06-1004 in Patients With Daibetic Macular Edema CU06-1004, Placebo Control - DME, Diabetic Macular Edema | Phase 2 | Not yet recruiting | Curacle Co., Ltd. | 156 | 2026-12-01 | 2026-10-23 |
| Effect of Dietary Fiber Supplementation on Systemic Inflammation and Clinical Parameters in COPD Dietary Fiber Supplementation, Placebo Control - Pulmonary Disease, Chronic Obstructive (COPD), Pulmonary Diseases | Not applicable | Not yet recruiting | Júnea Regina Pires Drews | 100 | 2026-11-01 | 2026-10-14 |
| A Phase 2a Study to Evaluate the Dose-response, Safety, Tolerability, Efficacy, and Population Pharmacokinetics of Intravenous NTS-521 Infusions in the Early Recovery Treatment From Acute Ischemic Stroke NTS-521, Placebo Control - Acute Ischemic Stroke | Phase 2 | Not yet recruiting | NeuroTrauma Sciences, LLC | 140 | 2026-10-31 | 2026-08-03 |
| Alcohol Sensitivity Among Older Adults Who Consume Alcohol Alcohol (Oral), Placebo Control - Healthy Adult Participants | Not applicable | Recruiting | University of Florida | 80 | 2026-10-03 | 2026-09-30 |
| Effect of Pelvic Floor Muscle Training Combined With Dietary Supplementation on Urinary Incontinence and Pelvic Floor Muscle Function in Women Incoxil, Placebo Control - Stress Incontinence Female | Not applicable | Not yet recruiting | FEMPHARMA Kft. | 100 | 2026-10-01 | 2026-10-15 |
| Daily, Encapsulated, Green Tea Extract to Mitigate Neuropathic Pain in Patients With Established Cancer-Associated Neuropathic Pain Green Tea Leaf Extract Decaffeinated, Placebo Control - Neuropathic Pain, Cancer Treatment | Phase 1 | Not yet recruiting | University of Alabama at Birmingham | 20 | 2026-09-30 | 2026-08-21 |
| The Effect of Urolithin A (Mitopure®) on Alzheimer's Disease Urolithin A, Placebo Control - Alzheimer's Disease (AD), Early Alzheimer's Disease | Not applicable | Recruiting | University Hospital, Akershus | 60 | 2026-09-26 | 2026-10-08 |
| "The Effect of Lavender Aromatherapy on Dental Anxiety" Lavender Aromatherapy, Placebo Control - Aromatherapy (Geranium Essential Oil) | Not applicable | Not yet recruiting | Dow University of Health Sciences | 68 | 2026-09-01 | 2026-09-10 |
| NAD Supplementation to Reduce the Incidence of Cardiac Surgery Associated Acute Kidney Injury Nicotinamide (NAM), Placebo control - Acute Kidney Injury | Not applicable | Not yet recruiting | Beth Israel Deaconess Medical Center | 20 | 2026-09-01 | 2026-07-31 |
| Finasteride and Cutibacterium Finasteride 1 mg, Placebo Control - Dihydrotestosterone, Periprosthetic Joint Infection (PJI) | Phase 4 | Not yet recruiting | University of Washington | 40 | 2026-08-31 | 2026-07-28 |
| NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease Droxidopa Oral Product, Placebo Control - Menkes Disease | Phase 1 / Phase 2 | Recruiting | Stephen G. Kaler | 6 | 2026-08-10 | 2026-10-05 |
| Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma. Dried chicory roots, Placebo - Melanoma (Skin) Stage IV, Melanoma (Skin Cancer) | Phase 2 | Recruiting | Radboud University Medical Center | 70 | 2026-07-31 | 2026-07-27 |
| A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of HSK39004 Inhalation Suspension in Patients With COPD HSK39004 Inhalation Suspension, Placebo control - COPD (Chronic Obstructive Pulmonary Disease) | Phase 3 | Not yet recruiting | Haisco Pharmaceutical Group Co., Ltd. | 387 | 2026-07-11 | 2026-06-22 |
| Efficacy of Recombinant Human G-CSF in Women With Unexplained Recurrent Miscarriage Placebo control, Recombinant G-CSF - Recurrent Pregnancy Loss, Recurrent Miscarriages | Phase 2 | Recruiting | Fakih IVF Fertility Center | 150 | 2026-07-10 | 2026-07-24 |
| Effectiveness of Chinese Herbal Medicine for Older Adults With Urinary Incontinence Chinese Herbal Medicine (CHM) supplement, Placebo Control - Urinary Incontinence (UI) | Not applicable | Not yet recruiting | Kwantlen Polytechnic University | 150 | 2026-06-01 | 2026-06-09 |
| Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HT31-1 for Treating ARDS HT31-1, Saline (0.9%, sterile, for infusion) - ARDS (Acute Respiratory Distress Syndrome) | Phase 1 | Recruiting | HTIC, Inc | 24 | 2026-05-28 | 2026-09-16 |
| A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Abdominal Surgery HSK55718 dose level1, HSK55718 dose level2, HSK55718 dose level 3 - Pain After Surgery | Phase 2 | Recruiting | Haisco Pharmaceutical Group Co., Ltd. | 200 | 2026-05-22 | 2026-05-28 |
| Dietary Supplements and Middle Aged Women (Collagen & Omega) Collagen peptides and omega-3, Placebo control - Cognition, Inflammation Biomarkers | Not applicable | Recruiting | Loughborough University | 34 | 2026-05-01 | 2026-08-03 |
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Obesity (9) · Diabetes Mellitus (8) · Motor Activity (8) · Alzheimer Disease (6) · Epilepsy (6) · Influenza, Human (6) · Acne Vulgaris (5) · Hypercholesterolemia (5) · Hypersensitivity (5) · Neoplasms (5) · Brain Injuries, Traumatic (4) · COVID-19 (4) · Diabetes Mellitus, Type 2 (4) · Osteoarthritis, Knee (4) · Overweight (4)
Jazz Pharmaceuticals (9) · Sun Pharmaceutical Industries, Inc. (8) · The University of Hong Kong (7) · GlaxoSmithKline (5) · Kessler Foundation (4) · Olistic Research Labs S.L. (4) · Sun Yat-sen University (4) · Vaxart (4) · Artu Biologicals (3) · Esperion Therapeutics, Inc. (3) · Hungkuang University (3) · Kolon TissueGene, Inc. (3) · McMaster University (3) · University of Maryland, Baltimore (3) · Colorado State University (2)
United States (115) · China (37) · United Kingdom (25) · Canada (21) · Germany (17) · Australia (14) · Spain (12) · Taiwan (11) · Czechia (9) · France (9) · Netherlands (9) · Poland (9) · South Korea (9) · Italy (8) · Brazil (7)
Natalie Yantovskiy (4) · Moon Jong Noh, PhD (3) · Ron Haberman, MD (3) · Zaidoon A. Al-Zubaidy (3) · Alan S. Lader, Ph.D. (2) · Christian Seiler, MD, Prof. (2) · Christopher J Lettieri, MD (2) · Gail Gauvreau, PhD (2) · Ho Cheung William Li (2) · Huilian Zhu, professor (2) · Michael Stoller, MD (2)
PMID 32609313, PMID 35916348, PMID 24450891, PMID 26208959, PMID 28269765, PMID 29854934, PMID 29854935, PMID 30412493, PMID 31824976, PMID 34265088, PMID 41276263, PMID 18598362, PMID 18788656, PMID 19567493, PMID 19920270, PMID 19968674, PMID 20018364, PMID 20131255, PMID 20576835, PMID 20632888, PMID 20880898, PMID 21127322, PMID 21285968, PMID 21861845, PMID 21899741, PMID 22736448, PMID 22821620, PMID 23113480, PMID 23200183, PMID 23357198, PMID 23587190, PMID 23967083, PMID 23998516, PMID 24151639, PMID 24186565, PMID 24237718, PMID 24379032, PMID 24937546, PMID 25424785, PMID 25440210, PMID 26333337, PMID 26467994, PMID 26677237, PMID 26685704, PMID 26833336, PMID 27091900, PMID 27173813, PMID 27413123, PMID 27506771, PMID 27648659
2014 (5), 2009 (2), 2015 (2), 2005 (1), 2016 (1), 2017 (1), 2023 (1), K23AG044441 (1), KL2TR002381 (1), P50NS044227 (1), R01AG073113 (1), R01DA019992 (1), R01GM116119 (1), R01MH024652 (1), R21AA032614 (1)