27 completed, 10 recruiting, 4 unknown, 3 terminated. 38 Not applicable, 5 Phase 2, 3 Phase 3, 2 Early Phase 1, 2 Phase 1.
Follow Placebo beverage: new trials by email Literature Review of Placebo beverage trials Research Report on Placebo beverage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder Kenetik, magnetic resonance imaging scan, Alcohol bar lab - Alcohol Use Disorder, Ketosis | Phase 2 / Phase 3 | Recruiting | University of Pennsylvania | 60 | 2026-12-01 | 2026-10-21 |
| Effects of Pre-Run Nutritional Supplements During a Fixed-Pace 5 km Treadmill Run Caffeine, L-Citrulline, Exogenous Ketone (Beta-Hydroxybutyrate) - Exercise Physiology, Nutritional Supplementation | Not applicable | Recruiting | St. Louis University | 20 | 2026-10-01 | 2026-10-02 |
| Hydration & Female Life Stages placebo beverage, electrolyte beverage - Dehydration, Menstruation | Not applicable | Recruiting | PepsiCo Global R&D | 72 | 2026-06-29 | 2026-09-21 |
| Carbohydrate Availability and Running Performance in Professional Male Footballers High-Carbohydrate Beverage, placebo beverage - Carbohydrate Intake and Exercise Performance | Not applicable | Completed | Göteborg University | 17 | 2026-04-01 | 2026-06-25 |
| Maple Syrup Carbohydrate Dose-Response on 20-km Cycling Time-Trial Performance Maple Syrup Beverages, placebo beverage, Pre-Trial Meals - Exercise, Endurance Cycling Performance | Not applicable | Not yet recruiting | Université de Montréal | 32 | 2026-02-01 | 2026-02-05 |
| Effects of an Elderberry-Based Functional Beverage on Exercise Performance, Muscle Structure, and the Gut-Muscle Axis Elderberry-Based Functional Beverage, Placebo Beverage - Exercise, Anthocyanins | Not applicable | Not yet recruiting | Burdur Mehmet Akif Ersoy University | 54 | 2025-11-01 | 2025-07-08 |
| Use of Maltodextrins in the ERAS Preoperative Fasting Protocol in Pediatric Surgery Maltodextrin Clear Liquid, Non-Sugared Clear Liquid - Preoperative Care, Anxiety | Not applicable | Recruiting | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | 200 | 2025-09-03 | 2026-07-06 |
| Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate - Healthy Adults, Mechanical Ventilation Dependence | Not applicable | Recruiting | Embry-Riddle Aeronautical University | 80 | 2025-09-01 | 2025-10-15 |
| Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder ketone supplement "D-beta-hydroxybutryric acid and R-1,3 butanediol" 12g of ketones,, magnetic resonance imaging session, Placebo beverage - Alcohol Use Disorder, Alcohol Withdrawal | Phase 2 / Phase 3 | Recruiting | University of Pennsylvania | 30 | 2025-08-01 | 2026-11-05 |
| A Study of Chios Mastic Water in Dyspepsia Chios mastic beverage, Placebo beverage - Dyspepsia | Not applicable | Recruiting | Harokopio University | 60 | 2025-07-10 | 2025-09-15 |
| Effects of Cranberry on Gut and Metabolic Health Cranberry beverage, Placebo beverage - Overweight/Obesity, Metabolic Syndrome | Not applicable | Recruiting | Laval University | 73 | 2025-07-07 | 2026-03-10 |
| The Effect of Short-term Supplementation of OliPhenolia® on Fat Oxidation Concentrated olive fruit water, Placebo, Anhydrous caffeine - Healthy | Not applicable | Recruiting | Anglia Ruskin University | 40 | 2025-05-30 | 2026-10-28 |
| Bioavailability of Ration Items Containing Tart Cherry Extract Fruit Bar, Powdered Drink, Commercially available 100% tart cherry juice - Bioavailability | Not applicable | Recruiting | United States Army Research Institute of Environmental Medicine | 15 | 2024-06-14 | 2025-12-29 |
| Internalized Stress in Relation to Alcohol Consumption Relevant Trier Social Stressor Test (TSST), Ethanol, Placebo Trier Social Stressor Test (TSST) - Stress, Physiological, Ethanol Intoxication | Early Phase 1 | Terminated | Texas Tech University | 165 | 2024-02-12 | 2025-05-08 |
| Ethanol Consumption in the Heat Placebo Beverage, Alcohol (Ethanol) - Alcohol Consumption, Heat Stress | Not applicable | Completed | Lakehead University | 28 | 2023-12-04 | 2026-09-24 |
| Elderberry Consumption and Human Health Elderberry Juice, Placebo Beverage - Obesity, Unspecified | Not applicable | Completed | Washington State University | 18 | 2023-02-27 | 2024-10-03 |
| Elderberries and Obesity Elderberry juice, Placebo beverage - Fuel Management | Not applicable | Completed | Washington State University | 10 | 2021-07-27 | 2023-02-10 |
| Familial Risk for Bipolar Disorder and Alcohol Sensitivity Alcohol beverage, Placebo beverage - Bipolar Disorder, Alcohol Drinking | Not applicable | Completed | University of Texas at Austin | 68 | 2021-05-13 | 2024-07-24 |
| Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors Alcohol beverage, Placebo beverage - Alcohol Consumption | Phase 1 | Completed | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 20 | 2021-03-18 | 2026-10-26 |
| Cardiometabolic Effects of Sweet Cherry Juice Cherry juice, Placebo beverage - Obesity, Metabolic Syndrome | Not applicable | Completed | USDA, Western Human Nutrition Research Center | 4 | 2019-10-01 | 2023-10-27 |
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Alcohol Drinking (5) · Alcoholism (4) · Inflammation (3) · Motor Activity (3) · Obesity (3) · Bipolar Disorder (2) · Insulin Resistance (2) · Ketosis (2) · Metabolic Syndrome (2) · Overweight (2) · Alcoholic Intoxication (1) · Alzheimer Disease (1) · Anxiety Disorders (1) · Behavior (1) · Binge-Eating Disorder (1)
PepsiCo Global R&D (3) · University of Texas at Austin (3) · Old Dominion University (2) · USDA, Western Human Nutrition Research Center (2) · United States Army Research Institute of Environmental Medicine (2) · University of Pennsylvania (2) · Washington State University (2) · Anglia Ruskin University (1) · Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria (1) · Burdur Mehmet Akif Ersoy University (1) · Embry-Riddle Aeronautical University (1) · Göteborg University (1) · Harokopio University (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · Icahn School of Medicine at Mount Sinai (1)
United States (25) · United Kingdom (5) · Canada (3) · Italy (2) · China (1) · Greece (1) · Serbia (1) · South Korea (1) · Sweden (1) · Turkey (Türkiye) (1)
Corinde Wiers, Ph.D. (2) · Elizabeth Lippard, PhD (2) · Aleksandra Konic Ristic, PhD (1) · Amanda G Smith, MD (1) · Amy C Ellis, PhD, RD (1) · Andy Jones, PhD (1) · Brandi C Fink, Ph.D. (1) · Brett Chaney, MD (1) · Conor P Kerley, BSc (1) · Darshan S Kelley, PhD (1) · Eric D. Claus, Ph.D. (1) · Francesca Danesi, PhD (1) · Francis Stephens, PhD (1) · Gary Williamson, PhD (1) · Giannis Arnaoutis, PhD (1)
PMID 26513587, PMID 26581682, PMID 26797134, PMID 27251185, PMID 31171016, PMID 32695957, PMID 33596852, PMID 33940082, PMID 34222308, PMID 34344546, PMID 35285906, PMID 36206822, PMID 36695842, PMID 37068952, PMID 37353164, PMID 37474761, PMID 37947276, PMID 40255128
P01ES006052 (1), R01AA031570 (1), R15HL173855 (1), R21AA031337 (1)