6 completed, 1 no longer available, 1 suspended, 1 unknown. 3 Not applicable, 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
Follow Pergolide: new trials by email Literature Review of Pergolide trials Research Report on Pergolide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MOTION, Safinamide in Early IPD, as add-on to Dopamine Agonist Safinamide (as add-on therapy) - Idiopathic Parkinson's Disease | Phase 3 | Completed | Newron Pharmaceuticals SPA | 679 | 2007-11-01 | 2013-10-29 |
| Adjuvant Therapy With Pergolide in Treating Cognitive Deficits in Schizophrenia Pergolide - Schizophrenia | Not applicable | Completed | Heidelberg University | 28 | 2003-10-01 | 2010-02-10 |
| Effective Adjunctive Use of Pergolide for Cognitive Impairment and Negative Symptoms in Schizophrenia Pergolide (drug) - Schizophrenia, Negative Symptoms | Suspended | Hamamatsu University | 20 | 2003-03-01 | 2005-09-20 | |
| Pergolide for Cognitive Symptoms in Schizotypal Personality Disorder Pergolide - Schizotypal Personality Disorder, Other Personality Disorders | Not applicable | Unknown | Bronx VA Medical Center | 2000-10-01 | 2005-11-21 | |
| Dose Response Trial of Pergolide for Cocaine Dependence - 1 Pergolide - Cocaine-Related Disorders | Phase 3 | Completed | Medical University of South Carolina | 1996-02-01 | 2018-05-16 | |
| Pergolide Treatment for Substance Abusers - 4 Pergolide - Cocaine-Related Disorders, Substance-Related Disorders | Phase 2 | Completed | National Institute on Drug Abuse (NIDA) | 1995-10-01 | 2017-01-12 | |
| Randomized Study of Pergolide in Children With Tourette Syndrome pergolide - Tourette Syndrome | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 74 | 1994-12-01 | 2015-03-25 |
| Compassionate Use Study of Pergolide in Patients With Parkinson's Disease Pergolide - Parkinson Disease | No longer available | Bausch Health Americas, Inc. | 2012-06-22 | |||
| IV Cocaine Abuse: A Laboratory Model - 4 Pergolide - Cocaine-Related Disorders | Phase 2 | Completed | National Institute on Drug Abuse (NIDA) | 2017-01-12 |
Cocaine-Related Disorders (3) · Cognition Disorders (2) · Parkinson Disease (2) · Schizophrenia (2) · Cognitive Dysfunction (1) · Depression (1) · Mental Disorders (1) · Neurologic Manifestations (1) · Rare Diseases (1) · Schizotypal Personality Disorder (1) · Substance-Related Disorders (1) · Tourette Syndrome (1)
National Institute on Drug Abuse (NIDA) (2) · Bausch Health Americas, Inc. (1) · Bronx VA Medical Center (1) · Children's Hospital Medical Center, Cincinnati (1) · Hamamatsu University (1) · Heidelberg University (1) · Medical University of South Carolina (1) · Newron Pharmaceuticals SPA (1)
United States (5) · Germany (2) · Argentina (1) · Brazil (1) · Bulgaria (1) · Canada (1) · Chile (1) · Colombia (1) · Croatia (1) · Czechia (1) · Finland (1) · India (1) · Italy (1) · Japan (1) · Mexico (1)
Floyd R. Sallee (1) · Herbert Kleber, M.D. (1) · Jonathan Willmer, MD (1) · Larry J Siever, MD (1) · Norio Mori, Ph.D (1) · Richard Foltin, Ph.D. (1) · Robert Malcolm, M.D. (1)
R01DA008355 (1)