16 completed, 3 recruiting, 3 unknown, 2 terminated. 11 Phase 2, 8 Phase 1, 5 Not applicable, 4 Phase 3, 1 Early Phase 1.
Follow PBS: new trials by email Literature Review of PBS trials Research Report on PBS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Addition of Maintenance Immunotherapy Compared to the Usual Treatment of Chemotherapy and Autologous Stem Cell Transplant Alone for High-risk Patients With Relapsed or Refractory Hodgkin Lymphoma 3-Dimensional Conformal Radiation Therapy, Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection - Recurrent Classic Hodgkin Lymphoma, Refractory Classic Hodgkin Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | National Cancer Institute (NCI) | 374 | 2026-12-04 | 2026-07-08 |
| BZLF1 Peptide Vaccine (OSU-2131) With QS-21 for the Prevention of Epstein-Barr Virus Related Cancer in Patients Awaiting Solid Organ Transplants Biospecimen Collection, Dulbecco''s Phosphate-Buffered Saline, Peptide Vaccine - Chronic Kidney Disease, Stage 4, Chronic Kidney Disease, Stage 5 | Phase 1 | Recruiting | Ohio State University Comprehensive Cancer Center | 55 | 2026-06-28 | 2026-07-02 |
| Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer Intensity-Modulated Radiation Therapy, Volume Modulated Arc Therapy, Pencil Beam Scanning - Astrocytoma, IDH-Mutant, Grade 3 | Phase 3 | Recruiting | Alliance for Clinical Trials in Oncology | 408 | 2026-06-24 | 2026-10-02 |
| Clinical Relevance of Modifying RANKL Signaling During Folliculogenesis Denosumab, PBS - Female Infertility, NF-κB Ligand | Not applicable | Recruiting | Peter Humaidan | 100 | 2025-08-01 | 2026-04-22 |
| 53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee TPX-100 200mg, Once weekly for 4 weeks, PBS - Osteoarthritis (OA) of the Knee | Phase 2 | Active not recruiting | OrthoTrophix, Inc | 270 | 2025-05-09 | 2026-02-17 |
| WJMSCs Anti-inflammatory Therapy in Acute Myocardial Infarction Intravenous infusion placebo, Intravenous infusion WJMSCs - Acute Myocardial Infarction | Phase 2 | Unknown | Navy General Hospital, Beijing | 200 | 2020-11-01 | 2020-09-16 |
| hCG-activated PBMC-therapy in RIF Patients Peripheral Blood Monouclear Cell, Phosphate Baffer Saline - Recurrent Implantation Failure | Not applicable | Completed | SCARM Institute, Tabriz, Iran | 100 | 2017-10-07 | 2019-08-26 |
| Safety and Efficacy Study of Herpes Simplex Virus Type 2 (HSV-2) Therapeutic DNA Vaccine VCL-HB01, Phosphate-buffered saline - Herpes Genitalis | Phase 2 | Completed | Vical | 261 | 2016-09-01 | 2019-02-27 |
| Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome ACI-24 low dose, ACI-24 high dose, Placebo - Down Syndrome | Phase 1 | Completed | AC Immune SA | 20 | 2016-03-01 | 2021-10-15 |
| Study on Efficacy and Safety of CBLB612 for Neutropenia Prophylaxis CBLB612, Placebo - Breast Cancer | Phase 2 | Completed | BioLab 612 LLC | 23 | 2015-12-01 | 2016-07-20 |
| Clinical Study of Safety and Tolerability of CBLB502 as a Neo-adjuvant Treatment in Patients With Colorectal Cancer CBLB502, Placebo - Colorectal Cancer | Phase 2 | Unknown | BioLab 612 LLC | 40 | 2015-11-01 | 2017-02-09 |
| Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy PBS, TLH _adnexal preservation - Uterine Fibroids, Adenomyosis | Not applicable | Unknown | University Magna Graecia | 167 | 2014-02-01 | 2016-11-18 |
| Safety and Efficacy Trial of DNA Vaccines to Treat Genital Herpes in Adults VCL-HB01, VCL-HM01, PBS - Genital Herpes Simplex Type 2 | Phase 1 / Phase 2 | Completed | Vical | 165 | 2013-12-01 | 2019-02-27 |
| Gel-One Treatment in Knee Osteoarthritis Gel-One, PBS - Osteoarthritis Knee | Not applicable | Completed | Seikagaku Corporation | 814 | 2013-08-01 | 2023-03-23 |
| Durolane Versus Phosphate Buffered Saline (PBS) in Knee Osteoarthritis Durolane, PBS - Knee Osteoarthritis | Not applicable | Terminated | Galderma R&D | 75 | 2012-12-01 | 2022-08-26 |
| Safety and Immunogenicity Study of Therapeutic HSV-2 Vaccine GEN-003 with Matrix M-2, GEN-003, Placebo - Genital Herpes Simplex Type 2 | Phase 1 / Phase 2 | Completed | Genocea Biosciences, Inc. | 143 | 2012-07-01 | 2018-06-01 |
| Proof of Concept Study With an Endothelin Receptor B Inhibitor (BQ-788) for Human Melanoma Endothelin Receptor B inhibitor BQ788, PBS - Melanoma | Early Phase 1 | Terminated | MelCure SA | 5 | 2011-05-01 | 2015-05-20 |
| Hymovis™ Versus Placebo in Knee Osteoarthritis Hymovis Intra-articular Injection, Phosphate Buffered Saline Injection - Knee Osteoarthritis | Phase 3 | Completed | Fidia Farmaceutici s.p.a. | 800 | 2011-03-01 | 2014-04-08 |
| Safety and Immunogenicity Study to Assess TDV, a Live Attenuated Tetravalent Vaccine for Prevention of Dengue Fever TDV - Low Dose, TDV - High Dose, Placebo - Dengue Fever | Phase 1 | Completed | Inviragen Inc. | 96 | 2010-10-11 | 2018-06-19 |
| Use of Dexmedetomidine to Reduce Emergence Delirium Incident in Children Dexmedetomidine, Saline - Agitation, Anesthesia | Phase 3 | Completed | St. Luke's-Roosevelt Hospital Center | 33 | 2009-08-01 | 2018-11-27 |
Showing 20 of 26. Sign in to see all of them.
Herpes Simplex (3) · Osteoarthritis (3) · Osteoarthritis, Knee (3) · Influenza in Birds (2) · Influenza, Human (2) · Adenomyosis (1) · Alzheimer Disease (1) · Astrocytoma (1) · Breast Neoplasms (1) · Cognitive Dysfunction (1) · Colorectal Neoplasms (1) · Dengue (1) · Dermatitis, Atopic (1) · Down Syndrome (1) · Emergence Delirium (1)
Vical (4) · BioLab 612 LLC (2) · AC Immune SA (1) · Aerovance, Inc. (1) · Alliance for Clinical Trials in Oncology (1) · Fidia Farmaceutici s.p.a. (1) · Galderma R&D (1) · Genocea Biosciences, Inc. (1) · Inviragen Inc. (1) · MelCure SA (1) · National Cancer Institute (NCI) (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Navy General Hospital, Beijing (1) · Ohio State University Comprehensive Cancer Center (1) · OrthoTrophix, Inc (1)
United States (15) · Colombia (1) · Denmark (1) · Iran (1) · Italy (1) · Japan (1) · Puerto Rico (1) · Russia (1) · United Kingdom (1)
Don Guterwill, BS, MT (2) · Aleksei G. Manikhas, MD PhD (1) · Cynthia Secchieri, PhD (1) · Darren Wilbraham, MBBS (1) · Dmitrii A. Krasnozhon, MD PhD (1) · Fulvio Zullo (1) · Ivan D Velez, MD, Ph.D. (1) · Jolie Narang, M.D. (1) · Lian Ru Gao, MD (1) · Mammen P Mammen, MD, FIDSA (1) · Mammen P. Mammen, Jr., MD, FIDSA (1) · Mehdi Yousefi, Ph.D (1) · Michael S. Rafii, MD, PhD (1) · Mohammad Nouri, Ph.D (1)
PMID 11756389, PMID 12525435, PMID 14629021, PMID 15670421, PMID 16820110, PMID 17021188, PMID 19467808, PMID 2064208, PMID 22035703, PMID 22464086, PMID 23028125, PMID 23909917, PMID 2419430, PMID 24289920, PMID 24354307, PMID 24408973, PMID 25087476, PMID 25731629, PMID 25820067, PMID 26330458, PMID 26469146, PMID 28329211, PMID 29644875, PMID 29714875, PMID 35532913, PMID 37314061, PMID 42720126
R01AG047922 (1), U10CA180820 (1)