15 unknown, 14 completed, 5 recruiting, 2 not yet recruiting. 27 Not applicable, 3 Phase 2, 3 Phase 4, 2 Early Phase 1, 2 Phase 3.
Follow Oxygen therapy: new trials by email Literature Review of Oxygen therapy trials Research Report on Oxygen therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Physiological Effect High-flow Tracheal Oxygen on Viscosity of Airway Mucus and Respiratory Effort in Patients Weaning From Invasive Mechanical Ventilation Oxygen therapy - Weaning From Mechanical Ventilation, Tracheostomy Weaning | Not applicable | Recruiting | Henrik Endeman | 20 | 2026-12-31 | 2026-10-01 |
| Trcheal High-flow for Weaning From Mechanical Ventilation Oxygen therapy - Tracheostomy, Mechanical Ventilation | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 500 | 2026-10-01 | 2026-07-20 |
| Advanced Respiratory Monitoring and Oxygen Therapy in Chronically Ill Patients With Acute Respiratory Failure High-Flow Nasal Cannula (HFNC) Oxygen Therapy, Oxygen therapy - Chronic Respiratory Failure, Cardiac Disease, Pulmonary Disease | Not applicable | Recruiting | Università degli Studi di Ferrara | 16 | 2025-11-05 | 2026-10-08 |
| Oxygen Therapy in Diabetic Kidney Disease Oxygen Therapy - Diabetic Kidney Disease | Not applicable | Not yet recruiting | Assiut University | 80 | 2025-08-01 | 2025-05-06 |
| The Effect of Oxygen Application With Double Nasal Cannula on Respiratory Complications OXYGEN THERAPY - Gastric Disease, Gastric Distress | Not applicable | Unknown | Inonu University | 200 | 2024-03-15 | 2024-02-22 |
| Supplemental Oxygen in Pulmonary Embolism (SO-PE) Oxygen Therapy, Non-rebreather mask - Pulmonary Embolism, Venous Thromboembolism | Early Phase 1 | Recruiting | Massachusetts General Hospital | 80 | 2023-10-01 | 2025-06-15 |
| Oxygen-Enhanced MRI for Generating Hypoxia Maps in Patients With Intracranial Tumors Magnetic Resonance Imaging, Oxygen Therapy - Intracranial Neoplasm | Not applicable | Withdrawn | OHSU Knight Cancer Institute | 2023-04-12 | 2025-11-14 | |
| Oxygen Therapy in Patients With Chronic Heart Failure With Reduced Ejection Fraction Oxygen Therapy - Chronic Heart Failure, Oxygen Deficiency | Not applicable | Terminated | Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta | 1 | 2022-07-01 | 2024-10-08 |
| Oxygen Therapy for Headache Oxygen therapy - Primary Headache Disorder | Completed | Aksaray University Training and Research Hospital | 132 | 2022-07-01 | 2022-10-04 | |
| Single Breath Counting Test for Acute Respiratory Failure in Emergency Department Oxygen Therapy, Non-Invasive Ventilation (NIV), Invasive Ventilation - Acute Respiratory Failure | Unknown | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | 600 | 2022-03-30 | 2024-02-14 | |
| Effect of Oxygen Therapy for Patients With Precapillary Pulmonary Hypertension Who Experience an Altitude Related Adverse Health Effect (ARAHE) During 30h Exposure to 2500m Oxygen Therapy - High Altitude Pulmonary Hypertension, Oxygen Therapy | Not applicable | Completed | University of Zurich | 9 | 2021-10-18 | 2022-05-11 |
| Early Application of Continuous Positive Airway Pressure in Coronavirus Patients at Risk of Obstructive Sleep Apnea CPAP ( Continuous positive airway pressure), oxygen therapy - Covid19, Obstructive Sleep Apnea | Not applicable | Completed | Mansoura University | 80 | 2021-08-01 | 2023-07-07 |
| CO2-Patterns During Hyperoxia and Physical Exercise in COPD Oxygen therapy, Medical Air, 10L/min O2 - COPD | Not applicable | Unknown | Schön Klinik Berchtesgadener Land | 55 | 2021-07-13 | 2021-07-14 |
| Covid-19 Patients Management During Home Isolation Oxygen therapy and physical therapy, Oxygen therapy - Covid19 | Not applicable | Unknown | Cairo University | 60 | 2021-06-30 | 2021-08-16 |
| Automatic Oxygen Titration in Patients After SARS-CoV-2 Infection Oxygen therapy - Post-COVID19 | Not applicable | Completed | Schön Klinik Berchtesgadener Land | 15 | 2021-04-13 | 2021-11-05 |
| Study Testing Convalescent Plasma vs Best Supportive Care high-titer anti-Sars-CoV-2 plasma, oxygen therapy - Pneumonia, Interstitial | Phase 1 | Withdrawn | Baylor Research Institute | 2020-04-17 | 2026-01-26 | |
| Management of Covid-19 Patients During Home Isolation Oxygen Therapy, Physical Therapy - Covid 19 | Not applicable | Unknown | Cairo University | 60 | 2020-03-15 | 2020-06-23 |
| Safety and Effectiveness of Mesenchymal Stem Cells in the Treatment of Pneumonia of Coronavirus Disease 2019 Oseltamivir, hormones, oxygen therapy - COVID-19 Pneumonia | Early Phase 1 | Unknown | Fuzhou General Hospital | 60 | 2020-03-01 | 2020-05-01 |
| Air as a Placebo: Increasing the Respiratory Performance of People With COPD Through Simple Expectations of Improvement Oxygen Therapy, Compressed Medical Air - Chronic Obstructive Pulmonary Disease | Not applicable | Unknown | Fondazione Don Carlo Gnocchi ETS | 102 | 2020-02-19 | 2022-02-01 |
| Optiflow THRIVE for Delivery of Oxygen to Patients During Total Intravenous Anesthesia While Undergoing Radiology Procedures Oxygen Therapy, Questionnaire Administration, Optiflow THRIVE - Obstructive Sleep Apnea | Not applicable | Completed | M.D. Anderson Cancer Center | 108 | 2019-10-04 | 2025-07-24 |
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Pulmonary Disease, Chronic Obstructive (6) · Dyspnea (4) · Respiratory Insufficiency (4) · COVID-19 (3) · Hypoxia (3) · Sleep Apnea, Obstructive (3) · Acute Lung Injury (2) · Lung Diseases, Interstitial (2) · Motor Activity (2) · Neoplasms (2) · Anemia, Sickle Cell (1) · Brain Neoplasms (1) · Bronchiolitis (1) · Coronary Artery Disease (1) · Coronavirus Infections (1)
M.D. Anderson Cancer Center (3) · Schön Klinik Berchtesgadener Land (3) · Cairo University (2) · Guangzhou Institute of Respiratory Disease (2) · OHSU Knight Cancer Institute (2) · Aalborg University Hospital (1) · Ain Shams University (1) · Aksaray University Training and Research Hospital (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria (1) · Bambino Gesù Hospital and Research Institute (1) · Baylor Research Institute (1) · Bayside Health (1) · Beijing Hospital (1)
Italy (7) · United States (6) · Egypt (5) · China (4) · Germany (3) · Denmark (2) · Spain (2) · Turkey (Türkiye) (2) · Australia (1) · Brazil (1) · Canada (1) · France (1) · Israel (1) · Netherlands (1) · Switzerland (1)
Ramon Barajas (2) · Andreas R Koczulla, Prof. Dr. med. (1) · Ashraf Anwar Thabet, Professor (1) · Bernardino Clavo, MD (1) · Bill Barger, ADHS (1) · Bodil S Rasmussen, MD (1) · Chen Wang, MD, PHD (1) · Christopher Kabrhel, MD, MPH (1) · David Hui (1) · David Kaye, MBBS PhD (1) · Dion Stub, MBBS (1) · Domenico Luca Grieco (1) · Frances Chung, MD (1) · Francesca Iodice, MD (1)
PMID 10377201, PMID 10508815, PMID 10787112, PMID 16281648, PMID 17503959, PMID 19232893, PMID 21037955, PMID 23406914, PMID 23899563, PMID 23935833, PMID 24462931, PMID 24912486, PMID 25442940, PMID 26002889, PMID 26164587, PMID 26215539, PMID 26536471, PMID 26719805, PMID 27940278, PMID 28007620, PMID 28069009, PMID 29283682, PMID 31484582, PMID 33289280, PMID 33819166, PMID 34656996, PMID 36366859, PMID 38079468, PMID 39532350, PMID 40648907, PMID 42251313
R37CA288577 (1)