12 completed, 4 unknown, 1 active not recruiting, 1 recruiting. 18 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 18 | Completed 12, Unknown 4, Active not recruiting 1, Recruiting 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
Follow oxybutynin: new trials by email Literature Review of oxybutynin trials Research Report on oxybutynin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial Evaluating the Clinical Efficacy and Safety of Hibero SR (Mirabegron) 50 mg and Ditropan (Oxybutynin Chloride) 10 mg in Children Between 5 and 18 Years With Overactive Bladder (OAB) Mirabegron 50 MG, Oxybutynin Chloride 5 MG - Overactive Bladder | Phase 2 | Unknown | Seoul National University Hospital | 44 | 2024-04-01 | 2024-03-08 |
| Pharyngeal Muscle Control Mechanisms of Atomoxetine-plus-oxybutynin in Obstructive Sleep Apnea Atomoxetine 80 mg plus Oxybutynin 5 mg, Atomoxetine 80 MG, Placebo - OSA | Phase 1 / Phase 2 | Completed | Brigham and Women's Hospital | 27 | 2023-12-01 | 2025-12-17 |
| Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome Atomoxetine and Oxybutynin (ato-oxy) - Obstructive Sleep Apnea, Down Syndrome | Phase 2 | Active not recruiting | University of Arizona | 36 | 2023-09-29 | 2026-04-07 |
| Topical Oxybutynin for Treatment of Hyperidrosis: Local or Systemic Effect? Topical oxybutynin spray, Topical placebo spray, Oral oxybutynin - Hyperhidrosis, Oxybutynin | Phase 2 | Unknown | Samantha Rodrigues Camargo Neves de Moura | 17 | 2022-09-26 | 2024-05-28 |
| Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin Therapy Atomoxetine, Oxybutynin - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Unknown | Brigham and Women's Hospital | 22 | 2022-05-05 | 2023-10-18 |
| Testing the Effects of Oxybutynin for the Treatment of Hot Flashes in Men Receiving Hormone Therapy for Prostate Cancer Oxybutynin Chloride, Placebo Administration, Quality-of-Life Assessment - Prostate Carcinoma | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 88 | 2021-10-28 | 2025-03-30 |
| Medications for Obstructive Sleep Apnea In Children With Down Syndrome Atomoxetine and oxybutynin (ato-oxy) - Obstructive Sleep Apnea, Down Syndrome | Phase 2 | Completed | University of Arizona | 22 | 2020-10-21 | 2025-08-19 |
| Early Oxybutinin Treatment for Boys With Posterior Urethral Valves Oxybutynin 1 mg/ml Syrup - Male Urogenital Diseases | Phase 2 | Recruiting | University Hospital, Bordeaux | 50 | 2020-09-10 | 2026-06-10 |
| A Novel Pharmacological Therapy for Obstructive Sleep Apnea Atomoxetine, Oxybutynin, Placebo - Sleep Apnea | Phase 2 | Completed | Brigham and Women's Hospital | 117 | 2019-09-03 | 2026-07-02 |
| Mirabegron and Oxybutynin Safety and Efficacy Trial in Spinal Cord Injury Oxybutynin Chloride IR, Mirabegron - Spinal Cord Injuries, Urinary Bladder, Neurogenic | Phase 2 | Unknown | Kessler Foundation | 62 | 2019-04-03 | 2019-12-17 |
| Atomoxetine and Oxybutynin in Obstructive Sleep Apnea Combination product of Atomoxetine and Oxybutynin, Placebo, 2 tablets - Obstructive Sleep Apnea (OSA) | Phase 1 / Phase 2 | Completed | Brigham and Women's Hospital | 22 | 2016-09-01 | 2019-01-29 |
| A Study of Fesoterodine and Oxybutynin on Cognitive Function in Mild Cognitive Impairment fesoterodine 4mg, Oxybutynin, placebo - Overactive Bladder, Mild Cognitive Impairment | Phase 2 | Completed | University of Alberta | 47 | 2016-08-01 | 2020-02-19 |
| A Relative Efficacy and Safety Study of OC Oral Solution for Sialorrhoea in Patients With Parkinson's Disease oxybutynin and clonidine oral solution treatment A, oxybutynin and clonidine oral solution treatment B, oxybutynin and clonidine oral solution treatment C - Sialorrhoea | Phase 2 | Completed | Orient Pharma Co., Ltd. | 24 | 2011-08-01 | 2023-04-10 |
| A Study to Compare Oxybutynin to a Placebo in Women and the Effect on Plantar Hyperhidrosis Oxybutynin 5 mg pills - Hyperhidrosis | Phase 2 | Completed | Federal University of São Paulo | 32 | 2010-03-01 | 2011-04-04 |
| A Study of Oxybutynin for the Treatment of Urge Urinary Incontinence oxybutynin - Urinary Incontinence, Urge | Phase 2 | Completed | FemmePharma Global Healthcare, Inc. | 45 | 2007-07-01 | 2009-10-15 |
| Desloratadine With Oxybutynin for the Treatment of Seasonal Allergic Rhinitis and Post-Nasal Drip (Study P04258)(COMPLETED) Desloratadine 2.5 mg, Oxybutynin 2.5 mg, Placebo for Desloratadine 2.5 mg - Post-nasal Drip, Seasonal Allergic Rhinitis | Phase 2 | Completed | Organon and Co | 540 | 2005-04-01 | 2022-02-16 |
| Cognitive Effects of Darifenacin and Oxybutynin Extended Release in Volunteers Aged 60 and Over Darifenacin, Oxybutynin, Placebo - Healthy Volunteers | Phase 2 | Completed | Novartis | 150 | 2005-02-01 | 2008-01-23 |
| The Effect of Extended-Release Oxybutynin Chloride on Vasomotor Symptoms in Healthy Post-Menopausal Women Placebo, Oxybutynin chloride - Menopause, Hot Flashes | Phase 2 | Completed | Ortho-McNeil Janssen Scientific Affairs, LLC | 148 | 2004-04-01 | 2012-12-12 |
Sleep Apnea, Obstructive (4) · Down Syndrome (2) · Hyperhidrosis (2) · Urinary Bladder, Overactive (2) · Cognitive Dysfunction (1) · Hot Flashes (1) · Male Urogenital Diseases (1) · Parkinson Disease (1) · Prostatic Neoplasms (1) · Rhinitis, Allergic, Seasonal (1) · Rhinorrhea (1) · Sialorrhea (1) · Skin Diseases (1) · Sleep Apnea Syndromes (1) · Spinal Cord Injuries (1)
Brigham and Women's Hospital (4) · University of Arizona (2) · Alliance for Clinical Trials in Oncology (1) · Federal University of São Paulo (1) · FemmePharma Global Healthcare, Inc. (1) · Kessler Foundation (1) · Novartis (1) · Organon and Co (1) · Orient Pharma Co., Ltd. (1) · Ortho-McNeil Janssen Scientific Affairs, LLC (1) · Samantha Rodrigues Camargo Neves de Moura (1) · Seoul National University Hospital (1) · University Hospital, Bordeaux (1) · University of Alberta (1)
United States (11) · Brazil (1) · Canada (1) · France (1) · South Korea (1)
Scott A Sands, PhD (3) · Aaron L Ellenbogen, DO, MPH (1) · Adrian S Wagg, MD (1) · Altair S Costa Jr, MD (1) · Bradley J. Stish, MD (1) · Chi-Tai Chang, PhD (1) · Daniel Combs, MD (1) · Dillon Gilbertson (1) · Eduardo Ramacciotti, MD, PhD (1) · Kwanjin Park, MD/PhD (1)
PMID 24519200, PMID 30395486, PMID 37555595, PMID 38402104, PMID 41587370
R01HL146697 (1), R33HL151254 (1), R61HL151254 (1), UG1CA189823 (1)