11 completed, 4 unknown, 1 active not recruiting, 1 not yet recruiting. 7 Phase 2, 6 Not applicable, 5 Phase 3, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 4, Unknown 2, Suspended 1 |
| Not applicable | 6 | Completed 3, Active not recruiting 1, Not yet recruiting 1, Unknown 1 |
| Phase 3 | 5 | Completed 5 |
| Phase 4 | 3 | Completed 2, Unknown 1 |
Follow Omega-3 Polyunsaturated Fatty Acids: new trials by email Literature Review of Omega-3 Polyunsaturated Fatty Acids trials Research Report on Omega-3 Polyunsaturated Fatty Acids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Fish Oil Supplementation on the Voice of Female Professional Voice Users (PVU) Omega-3 Polyunsaturated Fatty Acids - Mitigation of Acute Voice Changes Follwing Rigorous Voice Use | Not applicable | Not yet recruiting | Baylor University | 68 | 2026-10-01 | 2026-09-02 |
| Omega-3 Fatty Acid in the Prevention of Migraine Omega-3 polyunsaturated fatty acids, omega-6 PUFAs - Migraine, Omega-3 Polyunsaturated Fatty Acids | Not applicable | Completed | Kuang Tien General Hospital | 70 | 2020-12-03 | 2022-06-23 |
| Clinical Intervention on Cognitive Impairment of Schizophrenia With Metabolic Syndrome Omega-3 polyunsaturated fatty acids, Xbox aerobic exercise, transcranial direct current stimulation,tDCS - Schizophrenia | Phase 2 | Suspended | Shanghai Mental Health Center | 120 | 2020-10-01 | 2023-04-18 |
| Fish Oil-derived Omega-3 Fatty Acids on Gut Microbiota and Lipid Metabolome in Type 2 Diabetes Mellitus omega-3 polyunsaturated fatty acids, corn oil - Type 2 Diabetes Mellitus, Lipid Metabolism Disorder | Not applicable | Completed | Southeast University, China | 110 | 2019-06-08 | 2023-11-27 |
| Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis Omega-3 polyunsaturated fatty acids, Aspirin, Placebo - Aggressive Periodontitis | Phase 2 / Phase 3 | Completed | Universidade Estadual Paulista Júlio de Mesquita Filho | 38 | 2017-05-15 | 2021-12-28 |
| Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis Open flap debridement, Placebo, Omega-3 polyunsaturated fatty acids - Residual Disease, Aggressive Periodontitis | Phase 2 / Phase 3 | Completed | Universidade Estadual Paulista Júlio de Mesquita Filho | 34 | 2017-05-15 | 2020-11-17 |
| Effects of Omega-3 Plus Low-dose Aspirin as Adjunct to Periodontal Debridement for Chronic Periodontitis in Diabetics Placebo, 3g omega-3 plus 100mg aspirin daily for 60 days, omega-3 plus aspirin before periodontal therapy - Diabetes Mellitus, Chronic Periodontitis | Not applicable | Unknown | Universidade Estadual Paulista Júlio de Mesquita Filho | 75 | 2016-06-01 | 2016-11-23 |
| The Synchronized Trial on Expectant Mothers With Depressive Symptoms by Omega-3 PUFAs (SYNCHRO) Omega-3 polyunsaturated fatty acids, Olive oil - Pregnancy, Depression | Phase 3 | Completed | Tokyo Medical University | 108 | 2014-06-01 | 2017-12-21 |
| The Synchronized Trial on Expectant Mothers With Depressive Symptoms by Omega-3 PUFAs (SYNCHRO): Open Trial Omega-3 polyunsaturated fatty acids - Pregnancy, Depression | Phase 2 | Completed | Tokyo Medical University | 13 | 2013-10-01 | 2016-04-21 |
| Perioperative Application of Omega-3 Polyunsaturated Fatty Acids in Gastric Cancer Patients omega-3 polyunsaturated fatty acids - Gastric Cancer | Phase 4 | Unknown | Jian Suo | 100 | 2013-06-01 | 2013-07-30 |
| The Synchronized Trial on Expectant Mothers With Depressive Symptoms by Omega-3 PUFAs (SYNCHRO)in Tokyo: Open Trial Omega-3 polyunsaturated fatty acids - Depressive Symptoms | Not applicable | Completed | National Science and Technology Council, Taiwan | 5 | 2013-01-09 | 2025-06-10 |
| Omega-3 Fatty Acids and Insulin Sensitivity Omega-3, placebo - Insulin Resistance | Phase 3 | Completed | Mayo Clinic | 31 | 2012-12-21 | 2017-03-03 |
| Role of a Combination of Nutraceuticals (Ritmonutra) on Benign Supraventricular and Ventricular Arrhythmias Ritmonutra, placebo - Ventricular and Atrial Extrasytoles | Phase 4 | Completed | Federico II University | 1500 | 2012-12-01 | 2016-02-03 |
| Modulation of Esophageal Inflammation in Barrett's Esophagus by Omega-3 Fatty Acids Omega-3 polyunsaturated fatty acids, Placebo - Barrett's Esophagus, Obesity | Phase 4 | Completed | Mayo Clinic | 60 | 2012-11-01 | 2022-01-11 |
| Obesity and Asthma: Nutrigenetic Response to Omega-3 Fatty Acids omega-3 polyunsaturated fatty acids, Omega-3 Fatty Acid - Asthma, Obesity | Phase 2 / Phase 3 | Completed | Nemours Children's Clinic | 143 | 2010-07-01 | 2023-09-08 |
| Effects of Fish Oil and Red Wine on Oxidative Stress Biomarkers Fish Oil, Safflower Oil, Ethanol - Healthy | Not applicable | Active not recruiting | Carsten Skarke, MD | 40 | 2008-05-01 | 2026-02-24 |
| A Study of Omega-3 as an Augmentor of Antidepressant Treatment for Major Depression Omega-3 Polyunsaturated Fatty Acids - Major Depression | Phase 2 | Unknown | The University of New South Wales | 52 | 2006-02-01 | 2006-09-13 |
| A Study of Omega-3 as a Treatment for Major Depression Omega-3 Polyunsaturated Fatty Acids - Major Depression, Dysthymia | Phase 2 | Unknown | The University of New South Wales | 128 | 2005-10-01 | 2006-09-13 |
Depression (3) · Aggressive Periodontitis (2) · Depressive Disorder, Major (2) · Mood Disorders (2) · Obesity (2) · Arrhythmias, Cardiac (1) · Asthma (1) · Barrett Esophagus (1) · Chronic Periodontitis (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Dysthymic Disorder (1) · Insulin Resistance (1) · Lipid Metabolism Disorders (1) · Migraine Disorders (1)
Universidade Estadual Paulista Júlio de Mesquita Filho (3) · Mayo Clinic (2) · The University of New South Wales (2) · Tokyo Medical University (2) · Baylor University (1) · Carsten Skarke, MD (1) · Federico II University (1) · Jian Suo (1) · Kuang Tien General Hospital (1) · National Science and Technology Council, Taiwan (1) · Nemours Children's Clinic (1) · Shanghai Mental Health Center (1) · Southeast University, China (1)
United States (5) · Brazil (3) · Japan (3) · Taiwan (3) · Australia (2) · China (2) · Italy (1)
Daisuke Nishi, M.D., Ph.D. (2) · Gordon B Parker, Dsc MD PhD (2) · Kuan-Pin Su, M.D., Ph.D. (2) · Mauro Santamaria, Professor (2) · Anne Marie Rees, BSc MBBS (1) · Bruno Trimarco, MD (1) · Carsten Skarke, M.D. (1) · Chun-Pai Yang, Dr. (1) · Garret A FitzGerald, M.D. (1) · Ian Lanza, PhD (1) · Jason E. Lang, M.D. (1) · Mauro P Santamaria, PhD (1) · Prasad Iyer, MD (1) · Yan Chen (1)
PMID 20498621, PMID 20572767, PMID 25852206, PMID 27004997, PMID 27630014, PMID 28424185, PMID 28752805, PMID 30678465, PMID 32980834, PMID 34817851, PMID 40736087
5UL1TR000135 (1), KL2TR000136 (1), R15DC021053 (1), T32DK007352 (1), U24DK100469 (1)