19 completed, 11 unknown, 3 recruiting, 2 not yet recruiting. 31 Not applicable, 2 Phase 3, 2 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 31 | Completed 15, Unknown 9, Recruiting 3, Not yet recruiting 2, Terminated 2 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 4 | 2 | Completed 2 |
| Phase 1 | 1 | Unknown 1 |
Follow NIPPV: new trials by email Literature Review of NIPPV trials Research Report on NIPPV
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Noninvasive High Frequency Oscillatory Ventilation Versus Nasal Intermittent Mandatory Ventilation for Respiratory Distress Syndrome in Preterm Neonates Noninvasive High Frequency Oscillatory Ventilation, Nasal Intermittent Mandatory Ventilation - Respiratory Distress Syndrome (RDS), Newborn | Not applicable | Not yet recruiting | Aga Khan University | 158 | 2026-10-01 | 2026-09-23 |
| Noninvasive High Frequency Oscillatory Ventilation Versus Nasal Intermittent Mandatory Ventilation After Extubation in Neonates Noninvasive High Frequency Oscillatory Ventilation, Nasal Intermittent Mandatory Ventilation - Extubation Failure in Neonates | Not applicable | Not yet recruiting | Aga Khan University | 172 | 2026-10-01 | 2026-09-23 |
| WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen - Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS) | Not applicable | Recruiting | Ohio State University | 500 | 2026-08-18 | 2026-10-01 |
| Comparison of Continuous Positive Airway Pressure (CPAP) and Non-Invasive Positive Pressure Ventilation (NIPPV) in Preterm Newborns With Respiratory Distress Syndrome. NIPPV, CPAP - Respiratory Distress Syndrome (RDS) | Not applicable | Recruiting | Vilnius University | 150 | 2025-03-25 | 2025-05-13 |
| HFNC vs NIPPV Following Extubation High Flow Nasal Canula following extubation, Non-Invasive Positive Pressure Ventilation following extubation - Congenital Heart Disease | Not applicable | Recruiting | Emory University | 200 | 2025-02-27 | 2026-07-14 |
| HVNI for Successful Weaning in Respiratory Failure High Velocity Nasal Insufflation, Non-invasive positive pressure ventilation - Respiratory Failure, Weaning Failure | Not applicable | Unknown | Alexandria University | 40 | 2023-04-01 | 2023-05-11 |
| Non-invasive Secondary Respiratory Support in Late Preterm and Term Infants NCPAP, NIPPV, NHFOV - Neonates, Respiratory Distress | Not applicable | Completed | Alexandria University | 40 | 2021-07-01 | 2025-05-31 |
| Short Term Effects of Synchronized vs. Non-synchronized NIPPV in Preterm Infants. NIPPV, SNIPPV - Newborn Respiratory Distress, Preterm Infant | Not applicable | Completed | University of Turin, Italy | 30 | 2020-11-16 | 2026-09-15 |
| NHFOV vs NIPPV vs nCPAP in Preterm Infants With Respiratory Distress Syndrome nCPAP, NIPPV, NHFOV - Preterm Infant | Not applicable | Unknown | Jiulongpo No.1 People's Hospital | 684 | 2020-11-01 | 2020-11-18 |
| Comparison of Efficacy of Less Invasive Surfactant Treatment Under Nasal CPAP and Nasal IPPV NCPAP, NIPPV - Respiratory Distress Syndrome | Not applicable | Completed | Uludag University | 85 | 2020-10-01 | 2026-02-09 |
| Evaluation Of The Efficacy Of Four Different Non-invasive Ventilation Modes Performed In The Delivery Room HHHFNC, NCPAP, NIPPV - Respiratory Disease, Respiratory Insufficiency | Not applicable | Unknown | Kanuni Sultan Suleyman Training and Research Hospital | 100 | 2020-02-18 | 2020-02-24 |
| CPAP vs NIPPV: A COMPARATIVE EFFECTIVENESS RESEARCH CPAP - Respiratory Insufficiency Syndrome of Newborn | Completed | Canadian Neonatal Network | 1829 | 2019-10-01 | 2023-04-26 | |
| High Flow Nasal Cannula Versus Nasal Intermittent Positive Pressure (NIPPV) in Preterm Infants Vapotherm, NIPPV - Preterm Infant | Not applicable | Unknown | Carmel Medical Center | 130 | 2018-01-21 | 2021-02-09 |
| A Trial Comparing Noninvasive Ventilation Strategies in Preterm Infants Following Extubation NHFOV, NCPAP, NIPPV - Intubated Infants Were Intend to Extubation Using Noninvasive Ventilation Strategies | Not applicable | Completed | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 1493 | 2017-12-01 | 2021-09-30 |
| Comparison of Primary Extubation Failure Between NIPPV and NI-NAVA NAVA, NIPPV - Preterm Infant, BPD - Bronchopulmonary Dysplasia | Not applicable | Completed | University of Florida | 30 | 2017-10-23 | 2020-02-19 |
| CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure continuous positive airway pressure, nasal intermittent positive pressure ventilation - Prematurity, Respiratory Distress Syndrome | Not applicable | Terminated | Women and Infants Hospital of Rhode Island | 52 | 2017-09-30 | 2024-07-30 |
| Nasal Intermittent Positive Pressure Ventilation(NIPPV) vs Continuous Positive Airway Pressure for Respiratory Distress Syndrome NIPPV, NCPAP - Nasal Intermittent Positive Pressure Ventilation, Nasal Continuous Positive Airway Pressure | Not applicable | Unknown | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 1000 | 2017-08-01 | 2017-07-24 |
| Noninvasive Positive Pressure Ventilation in Overlap Syndrome NIPPV - COPD, Sleep Apnea Syndromes | Not applicable | Unknown | Chinese Academy of Medical Sciences, Fuwai Hospital | 292 | 2017-06-15 | 2017-06-14 |
| Anti-inflammatory Effect of Nocturnal NIPPV on Acute Asthma NIPPV, CPAP - Asthma Acute | Not applicable | Completed | National Institute of Respiratory Diseases, Mexico | 20 | 2017-06-01 | 2019-08-28 |
| n-CPAP Versus n-BiPAP and NIPPV for Postextubation in RDS in Preterms N-CPAP, n-BiPAP, NIPPV - Respiratory Distress Syndrome | Not applicable | Completed | Ain Shams University | 120 | 2017-05-01 | 2020-05-05 |
Showing 20 of 37. Sign in to see all of them.
Premature Birth (13) · Respiratory Distress Syndrome (11) · Respiratory Insufficiency (7) · Bronchopulmonary Dysplasia (5) · Respiratory Distress Syndrome, Newborn (4) · Dyspnea (3) · Hyaline Membrane Disease (2) · Pulmonary Disease, Chronic Obstructive (2) · Respiratory Aspiration (2) · Apnea (1) · Asthma (1) · Barotrauma (1) · Bradycardia (1) · Heart Defects, Congenital (1) · Obesity, Morbid (1)
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (3) · Aga Khan University (2) · Alexandria University (2) · Gao WeiWei (2) · Women and Infants Hospital of Rhode Island (2) · Ain Shams University (1) · Brooke Army Medical Center (1) · Canadian Neonatal Network (1) · Carmel Medical Center (1) · Chinese Academy of Medical Sciences, Fuwai Hospital (1) · Emory University (1) · Federal University of Minas Gerais (1) · Instituto Materno Infantil Prof. Fernando Figueira (1) · Jiulongpo No.1 People's Hospital (1) · Kanuni Sultan Suleyman Training and Research Hospital (1)
United States (9) · China (6) · Canada (3) · Egypt (3) · Turkey (Türkiye) (3) · Pakistan (2) · Austria (1) · Belgium (1) · Brazil (1) · India (1) · Ireland (1) · Israel (1) · Italy (1) · Lithuania (1) · Mexico (1)
Shi Yuan, PhD,MD (2) · Aaron Chiu, MD (1) · Abbot R Laptook, MD (1) · Alessandra Coscia, Prof. (1) · Ali S Hussain, FCPS (Paeds),FCPS Neonatology (1) · Ali S Hussain, FCPS Paediatrics, Neonatology (1) · Alok Nath, MD (1) · Asaad Beshish, MD (1) · Ayala Gover, MD (1) · Bradley Yoder, MD (1) · Brigitte Lemyre, MD (1) · David Millar, MD (1)
PMID 21262883, PMID 22474063, PMID 23944299, PMID 26135774, PMID 27976361, PMID 10685270, PMID 10830460, PMID 11335736, PMID 11433048, PMID 12650303, PMID 15141265, PMID 15475599, PMID 16632652, PMID 17050561, PMID 17404558, PMID 17452229, PMID 1750756, PMID 17804519, PMID 18512045, PMID 18549418, PMID 19253509, PMID 19523049, PMID 19935062, PMID 19948523, PMID 20420722, PMID 20857278, PMID 21287368, PMID 21493723, PMID 22137670, PMID 22301528, PMID 22954265, PMID 23056781, PMID 23255684, PMID 23989138, PMID 24039148, PMID 24238745, PMID 24378898, PMID 24875408, PMID 25227281, PMID 25318667, PMID 25709790, PMID 26162889, PMID 26178463, PMID 28146296, PMID 29275926, PMID 29435810, PMID 305471, PMID 31349833, PMID 32106721, PMID 34127040
U24HL175258 (1), UG3HL175260 (1)