5 completed, 1 recruiting, 1 unknown. 7 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Recruiting 1, Unknown 1 |
| Phase 3 | 3 | Completed 3 |
Follow Nefopam: new trials by email Literature Review of Nefopam trials Research Report on Nefopam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability and Efficacy of Nefopam Cream in Burn Patients Nefopam, Placebo (Vehicle) - Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn | Phase 2 | Completed | University of Alberta | 50 | 2022-07-10 | 2026-07-24 |
| Post-operative Analgesic Effect of Oral Nefopam Oral nefopam, Placebo - Postoperative Pain After a Total Knee Arthroplasty | Phase 2 | Recruiting | Hospices Civils de Lyon | 50 | 2021-06-29 | 2026-05-14 |
| Nefopam vs Tramadol in the Prevention of Post Anaesthetic Shivering Nefopam, Tramadol, Metoclopramide - Post Anaesthetic Shivering | Phase 2 | Unknown | Lagos State Health Service Commission | 130 | 2018-10-12 | 2018-07-17 |
| Comparison of Two Routes of Administration of a Multimodal Analgesic Protocol in Postoperative Cesarean Section Nefopam 20 MG/ML, "Nefopam (Acupan)" 20 MG/ML Injectable Solution, "Acetaminophen, (paracetamol)" 500Mg Tab - Cesarean Section; Complications, Wound, Infection (Following Delivery), Postoperative Pain | Phase 2 / Phase 3 | Completed | Centre de Maternité de Monastir | 200 | 2015-01-01 | 2018-08-15 |
| Prospective Randomized Trial Comparing the Effectiveness of Continuous Paravertebral Infusion of Local Anesthetics Versus Intravenous Patient-controlled Analgesia on Acute and Chronic Neuropathic Pain After VATS Lobectomy 0.5% ropivacaine, Fentanyl 500mcg + acupan 160mg + nasea 0.6mg - Lung Neoplasms, Postoperative Pain | Phase 2 | Completed | Yonsei University | 79 | 2012-10-04 | 2019-01-31 |
| Nefopam/Fentanyl Postoperative Intravenous Patient-Controlled-Analgesia Nefopam, Saline - Laparotomy | Phase 2 / Phase 3 | Completed | Seoul National University Hospital | 73 | 2012-10-01 | 2015-11-05 |
| Effects of Nefopam on Hyperalgesia After Cardiac Surgery Nefopam, néfopam, Placebo comparator - Hyperalgesia, Pain, Postoperative | Phase 2 / Phase 3 | Completed | University Hospital, Bordeaux | 90 | 2006-12-01 | 2010-05-28 |
Pain, Postoperative (4) · Agnosia (2) · Hyperalgesia (2) · Pain (2) · Burns (1) · Chronic Disease (1) · Cicatrix, Hypertrophic (1) · Infections (1) · Lung Neoplasms (1) · Wounds and Injuries (1)
Centre de Maternité de Monastir (1) · Hospices Civils de Lyon (1) · Lagos State Health Service Commission (1) · Seoul National University Hospital (1) · University Hospital, Bordeaux (1) · University of Alberta (1) · Yonsei University (1)
France (2) · Canada (1) · South Korea (1) · Tunisia (1)
Edward E Tredget, MD (1) · Maria Akintimoye (1) · Yong Chul Kim, MD., PhD. (1)