6 completed, 6 unknown, 2 active not recruiting, 2 terminated. 8 Not applicable, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Unknown 3, Active not recruiting 2, Completed 2, Terminated 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 4 | 1 | Terminated 1 |
Follow mitral valve surgery: new trials by email Literature Review of mitral valve surgery trials Research Report on mitral valve surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Role of cardIac magNeTic rEsonance in surGical Decision Making in Patients With Severe pRimAry miTral rEgurgitation mitral valve surgery, Clinical Follow up - Mitral Valve Prolapse, Mitral Regurgitation | Not applicable | Active not recruiting | Centro Cardiologico Monzino | 260 | 2025-12-01 | 2026-06-10 |
| Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery Mitral valve surgery - Mitral Regurgitation, Mitral Valve Prolapse | Recruiting | Karolinska Institutet | 90 | 2024-02-21 | 2025-09-11 | |
| Haemodynamics of Mitral Regurgitation Reduction Mitral valve surgery, Transcatheter mitral valve intervention - Mitral Regurgitation | Unknown | Guy's and St Thomas' NHS Foundation Trust | 60 | 2022-06-06 | 2022-06-03 | |
| Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY) Mitral valve repair, Transcatheter edge-to-edge repair - Mitral Valve Regurgitation | Not applicable | Active not recruiting | Annetine Gelijns | 450 | 2022-02-21 | 2026-09-30 |
| LOng-Term Fate of Moderate Aortic Regurgitation Left Untreated at the Time of Mitral Valve Surgery Mitral valve surgery, Aortic valve surgery - Aortic Regurgitation, Mitral Regurgitation | Completed | Michele De Bonis | 183 | 2021-03-24 | 2023-03-20 | |
| Mechanical Complications of Acute Myocardial Infarction During COVID-19 Pandemics Surgical repair, Percutaneous treatment, Mitral valve surgery - Ventricular Septal Rupture, Papillary Muscle Rupture | Completed | Maastricht University Medical Center | 130 | 2021-03-01 | 2023-06-12 | |
| Registry for Mitral Valve Surgery at Department of Cardiac Surgery University Hospital of Basel/ Switzerland mitral valve surgery - Mitral Valve Disease, Mitral Valve Surgery | Completed | University Hospital, Basel, Switzerland | 701 | 2018-04-28 | 2024-12-16 | |
| PROphylactic triCuspID Annuloplasty in Patients With Dilated Tricuspid Annulus Mitral valve surgery, Tricuspid valve annuloplasty - Tricuspid (Valve) Insufficiency (Rheumatic) | Not applicable | Unknown | Ettore Sansavini Health Science Foundation | 200 | 2017-05-17 | 2017-06-28 |
| MRI as a Predictor of Outcomes in Patients Undergoing Mitral Valve Surgery Mitral valve surgery - Mitral Valve Insufficiency | Unknown | Atlantic Health System | 100 | 2017-01-01 | 2018-01-11 | |
| High and Intermediate Risk Degenerative Mitral Regurgitation Treatment: A Trial Comparing MitraClip® to Surgical Therapy MitraClip®, Mitral valve Surgery - Mitral Valve Insufficiency | Phase 4 | Terminated | University of Zurich | 294 | 2015-04-01 | 2016-09-09 |
| Ablation of the Pulmonary Artery With High Pulmonary Hypertension During Mitral Valve Surgery Surgical ablation of ganglion plexus pulmonary artery., mitral valve surgery - Pulmonary Hypertension | Phase 1 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 30 | 2015-02-01 | 2015-09-23 |
| A Multicenter, Randomized, Controlled Study to Assess Mitral vAlve reconsTrucTion for advancEd Insufficiency of Functional or iscHemic ORigiN MitraClip system (Abbott Vascular, Menlo Park, USA), Mitral valve surgery - Mitral Valve Insufficiency | Not applicable | Unknown | Universitätsklinikum Köln | 210 | 2015-02-01 | 2017-08-01 |
| Ablation and Left Atrium Reduction During Mitral Valve Surgery for Atrial Fibrillation maze procedure, mitral valve surgery, left atrial reduction - Atrial Fibrillation | Not applicable | Completed | Meshalkin Research Institute of Pathology of Circulation | 120 | 2014-09-01 | 2017-09-11 |
| Magnetic Resonance Imaging for Cerebral Embolization During Minimal Invasive Mitral Valve Surgery Mitral valve surgery - Neurological Complications, Mitral Valve Insufficiency | Not applicable | Unknown | University of Turin, Italy | 80 | 2014-06-01 | 2016-08-04 |
| Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Insufficiency. myoectomy, Mitral valve surgery - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Completed | Meshalkin Research Institute of Pathology of Circulation | 82 | 2013-10-01 | 2015-07-02 |
| Evaluation of the Cardioblate CryoFlex Surgical Ablation System in Longstanding Persistent Atrial Fibrillation Cardioblate CryoFlex Surgical Ablation, Mitral Valve surgery, Medtronic Reveal XT Insertable Cardiac Monitor - Longstanding Persistent Atrial Fibrillation | Not applicable | Terminated | Medtronic Cardiac Rhythm and Heart Failure | 17 | 2011-11-01 | 2019-07-30 |
| Neurologic Outcome After Mitral Valve Surgery mitral valve surgery - Mitral Valve Reconstruction | Withdrawn | University Hospital, Basel, Switzerland | 2009-02-01 | 2022-04-20 | ||
| ACCESS-Europe A Two-Phase Observational Study of the MitraClip® System in Europe MitraClip, Medical Management, Mitral Valve Surgery - Mitral Valve (MV) Regurgitation | Completed | Abbott Medical Devices | 721 | 2008-10-01 | 2018-11-07 |
Mitral Valve Insufficiency (11) · Atrial Fibrillation (2) · Mitral Valve Prolapse (2) · Aortic Valve Insufficiency (1) · Cardiomyopathy, Hypertrophic (1) · Gastroesophageal Reflux (1) · Heart Rupture (1) · Hypertension, Pulmonary (1) · Mitral Valve Stenosis (1) · Tachycardia, Ventricular (1) · Tricuspid Valve Insufficiency (1) · Ventricular Septal Rupture (1)
Meshalkin Research Institute of Pathology of Circulation (3) · University Hospital, Basel, Switzerland (2) · Abbott Medical Devices (1) · Annetine Gelijns (1) · Atlantic Health System (1) · Centro Cardiologico Monzino (1) · Ettore Sansavini Health Science Foundation (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Karolinska Institutet (1) · Maastricht University Medical Center (1) · Medtronic Cardiac Rhythm and Heart Failure (1) · Michele De Bonis (1) · University of Turin, Italy (1) · University of Zurich (1) · Universitätsklinikum Köln (1)
Italy (6) · Germany (5) · Russia (3) · Switzerland (3) · Spain (2) · United States (2) · Canada (1) · Israel (1) · Netherlands (1) · Sweden (1) · United Kingdom (1)
Aleksandr V Bogachev-Prokophiev, MD PhD (1) · Aleksandr V Bogachev-Prokophiev, PhD (1) · Alexander V Bogachev-Prokophiev, PhD (1) · Barathi Sethuraman, PhD (1) · Eric Vang, MD (1) · Francesco Maisano, MD (1) · Francesco Maisano, Prof. (1) · Gianluca Pontone, MD (1) · Joanna Chikwe, MD (1) · Maria Salomone, MD (1) · Martin Grapow, Prof. Dr. MD (1) · Martin Grapow, Prof. MD (1) · Martin Leon, MD (1) · Patrick O'Gara, MD (1) · Stephan Baldus, Prof. Dr. med. (1)
PMID 21983306, PMID 22322574, PMID 23747789, PMID 24831647, PMID 28222779, PMID 28575282, PMID 39216093, PMID 40392571
2018 (2), U01HL088942 (1)