21 completed, 5 unknown, 4 terminated, 3 recruiting. 12 Phase 4, 8 Not applicable, 7 Phase 2, 3 Early Phase 1, 2 Phase 1.
Follow Micronized Progesterone: new trials by email Literature Review of Micronized Progesterone trials Research Report on Micronized Progesterone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Menopausal HT for Women Living With HIV (HoT) Transdermal estradiol gel, Micronized Progesterone, Placebo for estradiol gel - HIV Infection, Menopause | Phase 4 | Recruiting | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 105 | 2026-04-09 | 2026-05-22 |
| Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Overweight/Obesity and Impaired Glucose Homeostasis GLP-1 Receptor Agonist, Menopausal Hormone Therapy - Menopause, Type 2 Diabetes | Not applicable | Active not recruiting | Lia Bally | 96 | 2025-02-18 | 2026-10-16 |
| Adjunctive Vaginal Progesterone in Management of Preterm Labor Micronized progesterone - Preterm Labor | Phase 4 | Unknown | Chulalongkorn University | 48 | 2023-08-16 | 2023-08-30 |
| Rhythmic Estradiol and Bone Health Estradiol patch, Progesterone - Osteoporosis Risk, Menopause | Phase 4 | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 48 | 2023-07-19 | 2026-10-16 |
| Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion Micronized progesterone, Placebo, Flutamide - PCOS, Polycystic Ovary Syndrome | Early Phase 1 | Unknown | University of Virginia | 10 | 2022-10-26 | 2023-11-02 |
| Examining the Effects of Estradiol on Neural and Molecular Response to Reward Transdermal Estradiol, Micronized Progesterone, Matching Placebo Patch - Depression, Psychosis | Phase 4 | Recruiting | University of North Carolina, Chapel Hill | 103 | 2022-04-20 | 2026-04-29 |
| Pharmacokinetics of Progesterone in Pregnancy-2 micronized Progesterone - Pregnancy Related | Phase 1 | Terminated | Thomas Jefferson University | 3 | 2022-01-07 | 2022-05-26 |
| Oral Versus Vaginal Progesterone for Luteal Phase Supplementation in Frozen Embryo Transfer Cycles Dydrogesterone 10 MG Oral Tablet, Micronized progesterone - Frozen Embryo Transfer, Hormone Replacement Therapy | Phase 4 | Completed | CRG UZ Brussel | 150 | 2021-10-01 | 2024-06-14 |
| Neurobiology of Bulimia Nervosa Estradiol, Micronized progesterone, Leuprolide Acetate - Bulimia Nervosa | Phase 2 | Completed | University of North Carolina, Chapel Hill | 10 | 2020-02-24 | 2022-07-26 |
| Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model Leuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone - Perinatal Depression, Post Partum Depression | Phase 2 | Completed | University of North Carolina, Chapel Hill | 23 | 2020-01-02 | 2023-08-25 |
| Micronized Progesterone vs Gonadotropin-releasing Hormone (GnRH) Antagonist in Freeze-all IVF Cycles. GnRh antagonist, Micronized progesterone - Infertility, IVF | Not applicable | Completed | Fundacion Dexeus | 44 | 2019-09-25 | 2023-05-15 |
| Follicle Stimulating Hormone (FSH) Glycosylation in Women: Effect of Estradiol Estradiol Transdermal Product - Follicle Stimulating Hormone Glycosylation, Urinary FSH21/FSH24 Ratio | Phase 2 | Unknown | Eastern Virginia Medical School | 10 | 2019-07-03 | 2019-07-12 |
| Progesterone Versus Progesterone Plus Dydrogesterone in FET Micronized Progesterone, Micronized progesterone plus dydrogesterone - Infertility | Not applicable | Completed | Mỹ Đức Hospital | 1364 | 2019-06-26 | 2021-02-24 |
| Natural Cycle Versus Hormone Replacement Therapy Cycle for a Frozen-thawed Embryo Transfer in PGT Patients Estradiol Valerate, Micronized progesterone - Miscarriage, Frozen Embryo Transfer | Phase 4 | Terminated | CRG UZ Brussel | 362 | 2019-05-25 | 2025-01-28 |
| Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI Dydrogesterone Oral Tablet, Micronized progesterone, Placebo Dydrogesterone oral tablet - Infertility, Female, Infertility | Phase 4 | Completed | CRG UZ Brussel | 30 | 2019-05-01 | 2020-12-17 |
| Blocking Mifepristone Action With Progesterone Mifepristone 200 MG, micronized Progesterone, Placebo oral capsule - Pregnancy, Unwanted | Phase 1 / Phase 2 | Terminated | University of California, Davis | 12 | 2019-02-11 | 2020-01-22 |
| Natural Versus Artificial Cycle for Frozen-Thawed Embryo Transfer Natural cycle, Estradiol Valerate, Micronized progesterone - Embryo Transfer | Phase 4 | Completed | Universitaire Ziekenhuizen KU Leuven | 554 | 2018-09-25 | 2025-02-28 |
| Non-interventional Study of Therapy for Threatened Miscarriage Micronized progesterone, Dydrogesterone - Threatened Miscarriage | Completed | Besins Healthcare | 1241 | 2017-10-16 | 2018-01-18 | |
| Vaginal Versus Intramuscular Progesterone for the Prevention of Recurrent Preterm Birth Vaginal Progesterone, Intramuscular Progesterone (17 alpha hydroxprogesterone caproate) - Premature Birth | Phase 4 | Completed | Thomas Jefferson University | 210 | 2016-09-01 | 2026-02-24 |
| Hyperandrogenemia and Altered Day-night LH Pulse Patterns Micronized progesterone, Spironolactone, Placebo - Hyperandrogenism, Polycystic Ovary Syndrome | Early Phase 1 | Recruiting | University of Virginia | 32 | 2016-07-21 | 2025-08-05 |
Showing 20 of 34. Sign in to see all of them.
Premature Birth (5) · Infertility (4) · Depression (3) · Mood Disorders (3) · Polycystic Ovary Syndrome (3) · Abortion, Spontaneous (2) · Depression, Postpartum (2) · Depressive Disorder (2) · Hyperandrogenism (2) · Infertility, Female (2) · Mental Disorders (2) · Obstetric Labor, Premature (2) · Abortion, Threatened (1) · Amenorrhea (1) · Anhedonia (1)
University of North Carolina, Chapel Hill (5) · CRG UZ Brussel (3) · Fundacion Dexeus (2) · Thomas Jefferson University (2) · University of Virginia (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Besins Healthcare (1) · Chiang Mai University (1) · Chulalongkorn University (1) · Duramed Research (1) · Eastern Virginia Medical School (1) · Ghamra Military Hospital (1) · HaEmek Medical Center, Israel (1) · Lia Bally (1)
United States (15) · Belgium (4) · Thailand (3) · Austria (1) · Egypt (1) · Israel (1) · Italy (1) · Netherlands (1) · Russia (1) · Spain (1) · Switzerland (1) · Vietnam (1)
Crystal E Schiller, PhD (2) · Ahmed Abdel-Aziz (1) · Christine Burt Solorzano, M.D. (1) · Christophe Blockeel (1) · Christopher M McCartney, MD (1) · Crystal E Schiller, Ph.D. (1) · Crystal Schiller, PhD (1) · David R Rubinow, M.D. (1) · Dorothy Hatsukami, Ph.D. (1) · Fabio Facchinetti, M.D. (1) · Gabriel Dichter, PhD (1) · Herman Tournaye, PhD, MD (1) · Igor Manuhin, PhD (1) · Janet Hall, MD (1)
PMID 20719809, PMID 24845171, PMID 26003056, PMID 26921136, PMID 27741193, PMID 28594783, PMID 28609128, PMID 28949010, PMID 30289507, PMID 30649404, PMID 31809439, PMID 32016427, PMID 32216490, PMID 35189093, PMID 36782063, PMID 36855177, PMID 37372414, PMID 38498835, PMID 42081915, PMID 42315758
2018 (2), 2009 (1), K12HD001441 (1), K23MH105569 (1), P50HD028934 (1), R01HD102060 (1), R01MH128238 (1), R21MH101409 (1), R21MH119615 (1), R21MH121726 (1), UM1AI068636 (1)