11 unknown, 9 completed, 4 terminated, 3 not yet recruiting. 23 Phase 1, 20 Phase 2, 3 Phase 3, 1 Phase 4.
Follow mesenchymal stromal cells: new trials by email Literature Review of mesenchymal stromal cells trials Research Report on mesenchymal stromal cells
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Stem Cells to Treat Perinatal Brain Injury to Combat Cerebral Palsy MSC, marrow, Placebo - Perinatal Arterial Ischemic Stroke, Perinatal Asphyxia | Phase 2 / Phase 3 | Not yet recruiting | UMC Utrecht | 162 | 2027-04-01 | 2026-09-21 |
| Mesenchymal Stromal Cell Therapy to Prevent Bronchopulmonary Dysplasia in Extreme Preterm Infants Human Allogenic Umbilical Cord Mesenchymal Stromal Cells, Sham procedure control - Bronchopulmonary Dysplasia (BPD), ELGAN (22-28SA) | Phase 2 | Not yet recruiting | Ottawa Hospital Research Institute | 168 | 2025-10-01 | 2025-07-10 |
| Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplantation mesenchymal stromal cells - MSC | Phase 4 | Not yet recruiting | ShiCang Yu | 68 | 2024-01-01 | 2023-12-15 |
| Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells Mesenchymal Stromal Cells, Control Solution - Corneal Ulcer | Phase 2 | Recruiting | University of Illinois at Chicago | 38 | 2023-09-29 | 2025-12-16 |
| Combination of Conditioned Medium and Umbilical Cord-Mesenchymal Stem Cells Therapy for Acute Stroke Infarct Conditioned Medium, Umbilical Cord Mesenchymal Stem Cells, Neurologic and Neutrophic Drugs - Ischemic Stroke | Phase 1 / Phase 2 | Active not recruiting | PT. Prodia Stem Cell Indonesia | 15 | 2022-05-30 | 2026-02-25 |
| Mesenchymal Stromal Cells as Treatment for Digital Ulcers in Systemic Sclerosis Mesenchymal stromal cells, Placebo - Systemic Sclerosis, Digital Ulcer | Phase 1 / Phase 2 | Recruiting | UMC Utrecht | 20 | 2021-10-06 | 2025-09-10 |
| Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease) Mesenchymal Stromal Cells, Supportive Care - Sars-CoV2, Acute Respiratory Distress Syndrome | Phase 1 / Phase 2 | Completed | Baylor College of Medicine | 28 | 2021-02-12 | 2026-10-21 |
| Double-blind, Randomized, Controlled Clinical Trial to Assess Efficacy of MSC in Patients With COVID-19 ARDS Mesenchymal stromal cells, Placebo - Acute Respiratory Distress Syndrome, COVID-19 Pneumonia | Phase 2 | Completed | Cristina Avendaño Solá | 20 | 2020-09-15 | 2026-03-17 |
| Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19) Mesenchymal stromal cells, Placebo - Acute Respiratory Distress Syndrome, ARDS (Moderate or Severe) | Phase 2 | Completed | Masonic Cancer Center, University of Minnesota | 8 | 2020-07-30 | 2025-01-29 |
| Mesenchymal Stromal Cell Therapy for Severe Covid-19 Infection Mesenchymal stromal cells - Coronavirus Infection | Phase 1 / Phase 2 | Unknown | University of Liege | 20 | 2020-06-12 | 2024-05-09 |
| Cellular Immuno-Therapy for COVID-19 Acute Respiratory Distress Syndrome Mesenchymal Stromal Cells - Acute Respiratory Distress Syndrome, Covid19 | Phase 1 / Phase 2 | Completed | Ottawa Hospital Research Institute | 15 | 2020-05-15 | 2021-04-26 |
| Bone Marrow Derived Allogeneic Mesenchymal Stromal Cells to Non-healing Diabetic Foot Wounds mesenchymal stromal cells - Diabetic Foot Ulcer | Phase 1 | Terminated | Steno Diabetes Center Copenhagen | 2 | 2018-06-01 | 2020-08-19 |
| MSC Intratissular Injection in Crohn Disease Patients Mesenchymal Stromal Cells - Efficacy and Safety | Phase 1 / Phase 2 | Recruiting | University of Liege | 60 | 2018-01-15 | 2024-12-12 |
| NEPHSTROM for Diabetic Kidney Disease Mesenchymal Stromal Cells, Placebo - Diabetic Kidney Disease | Phase 1 / Phase 2 | Terminated | Mario Negri Institute for Pharmacological Research | 29 | 2017-12-11 | 2024-11-29 |
| Phase 1 Crohn's Pediatric Sub-study of MSC AFP Only 1 arm: treatment with MSC-AFP - Perianal Fistula | Phase 1 | Withdrawn | William A. Faubion, M.D. | 2017-07-01 | 2017-07-06 | |
| Autologous Cell Therapy After Stroke autologous bone marrow mononuclear cell transfusion, marrow stromal cells, placebo - Stroke | Phase 1 | Withdrawn | University of California, Irvine | 2016-01-01 | 2016-02-04 | |
| MSC and Kidney Transplant Tolerance (Phase A) Mesenchymal Stromal Cells - Chronic Renal Failure | Phase 1 | Unknown | Monia Lorini | 22 | 2015-09-01 | 2018-04-06 |
| Mesenchymal Stromal Cells in Adults With Recessive Dystrophic Epidermolysis Bullosa Mesenchymal stromal cells - Recessive Dystrophic Epidermolysis Bullosa | Phase 1 / Phase 2 | Unknown | King's College London | 10 | 2015-06-01 | 2017-03-03 |
| Allogeneic Mesenchymal Stromal Cell Therapy in Renal Transplant Recipients mesenchymal stromal cells - Rejection, Graft Loss | Phase 1 | Completed | Leiden University Medical Center | 10 | 2015-03-01 | 2019-07-02 |
| Treatment of Chronic Graft-Versus-Host Disease With Mesenchymal Stromal Cells Mesenchymal Stromal Cells - Chronic Graft-Versus-Host Disease | Phase 3 | Unknown | Guangdong Provincial People's Hospital | 130 | 2014-10-01 | 2014-11-14 |
Showing 20 of 34. Sign in to see all of them.
Respiratory Distress Syndrome (5) · COVID-19 (3) · Graft vs Host Disease (3) · Coronavirus Infections (2) · Anemia, Diamond-Blackfan (1) · Anemia, Sickle Cell (1) · Bronchiolitis Obliterans Syndrome (1) · Bronchopulmonary Dysplasia (1) · Corneal Ulcer (1) · Cytokine Release Syndrome (1) · Diabetes Mellitus (1) · Diabetic Foot (1) · Diabetic Nephropathies (1) · Disease Progression (1) · Epidermolysis Bullosa Dystrophica (1)
Karolinska Institutet (2) · Leiden University Medical Center (2) · Mario Negri Institute for Pharmacological Research (2) · Monia Lorini (2) · National Research Center for Hematology, Russia (2) · Ottawa Hospital Research Institute (2) · UMC Utrecht (2) · University of Liege (2) · Baylor College of Medicine (1) · Copenhagen University Hospital, Rigshospitalet (1) · Cristina Avendaño Solá (1) · Ettore Biagi, MD (1) · Guangdong Provincial People's Hospital (1) · Imperial College London (1) · Karolinska University Hospital (1)
United States (7) · Italy (5) · Netherlands (3) · Sweden (3) · United Kingdom (3) · Belgium (2) · Canada (2) · China (2) · Denmark (2) · Russia (2) · India (1) · Indonesia (1) · Ireland (1) · Spain (1)
Giuseppe Remuzzi, MD (4) · Alessandro Rambaldi, MD (3) · Martino Introna, MD (3) · Norberto Perico, MD (3) · Federica Casiraghi (2) · Giovanni Rota, MD (2) · Marlies EJ Reinders, MD/PhD (2) · Ali R Djalilian, MD (1) · Alix Seif, MD (1) · Antonio Pinna, MD (1) · Aruna Rakha, PhD. (1) · Charlotte E Joslin, OD, PhD (1) · Claudio Velati, MD (1) · Cristina Avedano-Sola, MD, PhD (1)
PMID 23349326, PMID 24321746, PMID 24370862, PMID 25491391, PMID 26537851, PMID 29333165, PMID 29963053, PMID 30127049, PMID 31072380, PMID 31711513, PMID 32573983, PMID 33370477, PMID 35860245, PMID 37426430, PMID 37560967, PMID 37783947, PMID 38409332, PMID 40374867, PMID 42409407
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