8 completed, 4 unknown, 2 not yet recruiting, 2 recruiting. 6 Phase 2, 6 Phase 3, 3 Not applicable, 2 Phase 4, 1 Early Phase 1.
Follow Melatonin 10 MG: new trials by email Literature Review of Melatonin 10 MG trials Research Report on Melatonin 10 MG
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Melatonin on Left Ventricular Reverse Remodeling and Inflammation in Peripartum Cardiomyopathy Melatonin 10 MG, Selenium, Placebo - Ppm, Cardiomyopathy | Not applicable | Not yet recruiting | Tanta University | 25 | 2026-12-20 | 2026-01-12 |
| Comparison Between the Effect of Two Different Doses of Oral Melatonin on Sleep Quality After Total Hip Arthroplasty Melatonin 5 MG, Melatonin 10 MG, Placebo - Sleep Disturbance | Early Phase 1 | Not yet recruiting | Benha University | 150 | 2026-08-04 | 2026-07-29 |
| Melatonin on Post Operative Pain After CS Melatonin 5 mg, Melatonin 10 mg, Placebo - Pain Management, Pain After Surgery | Not applicable | Completed | Benha University | 60 | 2025-10-10 | 2026-07-14 |
| Melatonin for Patients With Chronic Low Back Pain Melatonin 10 mg, Placebo - Chronic Low-back Pain (cLBP) | Phase 3 | Active not recruiting | Bart Koes | 222 | 2025-04-11 | 2026-09-09 |
| Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy Melatonin 10 MG, Placebo - Cardiomyopathies | Phase 3 | Recruiting | Tanta University | 46 | 2025-02-20 | 2025-03-26 |
| Melatonin fOr CHronic bAck Pain (The MOCHA Trial) Melatonin 10 MG, Placebo - Back Pain Lower Back Chronic, Insomnia | Phase 3 | Completed | Odense University Hospital | 220 | 2024-12-11 | 2026-04-22 |
| Analgesic Effect of Melatonin and Vitamin C Administration, Alone or In Combination in Major Abdominal Surgery. Melatonin 10 MG, Vitamin C - Postoperative Pain | Not applicable | Unknown | Cairo University | 60 | 2024-04-27 | 2024-04-19 |
| Cerebroprotective Effect of Melatonin in Stroke Melatonin 10 MG, Placebo - Stroke, Acute Ischemic, Strokes Thrombotic | Phase 3 | Unknown | Coordinación de Investigación en Salud, Mexico | 100 | 2024-03-01 | 2024-03-05 |
| Melatonin As an Analgesic in Preterm Neonate Melatonin 10 mg, Placebo - Preterm Neonate Analgesia | Phase 2 | Completed | Ain Shams University | 40 | 2022-08-20 | 2025-01-16 |
| Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery Melatonin 10 MG, Lactose pill - Pain, Postoperative, Narcotic Use | Phase 2 | Completed | Montefiore Medical Center | 60 | 2021-11-16 | 2026-01-30 |
| The Effects of Melatonin Treatment on Bone, Marrow, Sleep and Blood Pressure Melatonin 10 MG, Placebo - Osteoporosis, Postmenopausal | Phase 4 | Unknown | University of Aarhus | 40 | 2021-05-01 | 2021-04-29 |
| Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction Placebo, Melatonin 10 MG - Fetal Growth Retardation, Stillbirth and Fetal Death | Phase 3 | Recruiting | Monash University | 336 | 2019-05-29 | 2025-06-06 |
| Effect of Melatonin on Reduction of Pelvic Pain Melatonin 10 mg, Placebo, Melatonin 20 mg - Dysmenorrhea, Endometriosis | Phase 2 | Completed | Karolinska Institutet | 80 | 2019-03-15 | 2022-04-05 |
| Effect of Melatonin on Cardiovascular and Muscle Mass and Function in Patients With Heart Failure Melatonin 10 mg, Placebo Oral Tablet - Heart Failure With Reduced Ejection Fraction | Phase 2 | Unknown | Isfahan University of Medical Sciences | 90 | 2018-11-30 | 2019-03-28 |
| Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis Melatonin 10 mg, Conventional treatment of neonatal sepsis - Neonatal Sepsis | Phase 1 / Phase 2 | Completed | Mohamed Hussein Metwally | 55 | 2015-11-26 | 2017-09-27 |
| The Analgesic Effects of Melatonin Melatonin 10 mg, Melatonin 100 mg, Placebo - Analgesia, Antihyperalgesia | Phase 2 / Phase 3 | Completed | Lars Peter Holst Andersen | 36 | 2013-08-01 | 2014-10-22 |
| The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment Melatonin 10 mg, Placebo - Hepatopathy | Phase 4 | Completed | Medical University of Lodz | 60 | 2012-09-01 | 2017-04-20 |
Agnosia (3) · Cardiomyopathies (2) · Pain, Postoperative (2) · Digestive System Diseases (1) · Dysmenorrhea (1) · Endometriosis (1) · Fetal Death (1) · Fetal Growth Retardation (1) · Heart Failure (1) · Ischemic Stroke (1) · Muscular Atrophy (1) · Neonatal Sepsis (1) · Osteoporosis, Postmenopausal (1) · Parasomnias (1) · Premature Birth (1)
Benha University (2) · Tanta University (2) · Ain Shams University (1) · Bart Koes (1) · Cairo University (1) · Coordinación de Investigación en Salud, Mexico (1) · Isfahan University of Medical Sciences (1) · Karolinska Institutet (1) · Lars Peter Holst Andersen (1) · Medical University of Lodz (1) · Mohamed Hussein Metwally (1) · Monash University (1) · Montefiore Medical Center (1) · Odense University Hospital (1) · University of Aarhus (1)
Egypt (5) · Denmark (2) · Australia (1) · Iran (1) · Mexico (1) · Netherlands (1) · New Zealand (1) · Sweden (1) · United States (1)
Anne Kristine Amstrup (1) · Jason Baker, DMD (1) · Karin Due Bruun, PhD (1) · Kirsten Palmer, PhD (1) · Lars P.H. Andersen, MD (1) · Masoumeh Sadeghi, MD (1) · Waleed Hamimy, MD (1)
PMID 26893170, PMID 34668986, PMID 37267394, PMID 41250112
2023 (1)