81 completed, 31 unknown, 23 recruiting, 10 not yet recruiting. 137 Not applicable, 6 Phase 4, 4 Phase 2, 2 Phase 3, 1 Phase 1.
Follow Mediterranean Diet: new trials by email Literature Review of Mediterranean Diet trials Research Report on Mediterranean Diet
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PRehabilitation Intervention to Modify Eating for Breast Cancer Patients (PRIME) Mediterranean Diet - Breast Cancer | Not applicable | Not yet recruiting | H. Lee Moffitt Cancer Center and Research Institute | 20 | 2026-09-01 | 2026-09-15 |
| Gastrointestinal Response of Pediatric Cystic Fibrosis Patients on Mediterranean Diet Mediterranean diet - Cystic Fibrosis (CF), Cystic Fibrosis Gastrointestinal Disease | Not applicable | Recruiting | Dartmouth-Hitchcock Medical Center | 20 | 2026-09-01 | 2026-07-02 |
| Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS Metformin, İnositol, Folic Acid - PCOS (Polycystic Ovary Syndrome), Insulin Resistance | Not applicable | Recruiting | Dicle University | 90 | 2026-08-13 | 2026-10-16 |
| High-intensity Interval Training Versus Moderate Intensity Continuous Training on Gut Microbiota in Non-alcoholic Fatty Liver High intensity interval training, moderate intensity continuous training, Mediterranean diet - Non-alcoholic Fatty Liver | Not applicable | Not yet recruiting | Horus University | 60 | 2026-07-10 | 2026-07-13 |
| Comparative Effects of Carnivore and Mediterranean-style Diets on LDL Aggregation and Cardiometabolic Health Carnivore Diet, Mediterranean Diet - Atherosclerosis Cardiovascular Disease, Metabolic Syndrome | Not applicable | Not yet recruiting | Liverpool John Moores University | 30 | 2026-06-01 | 2026-03-13 |
| Mediterranean Diet and Time-Restricted Feeding in Ulcerative Colitis Remission Mediterranean Diet, Mediterranean Diet + Time-Restricted Feeding, Standard Dietary Advice - Ulcerative Colitis (Disorder), Inflammatory Bowel Disease (IBD) | Not applicable | Recruiting | Pontificia Universidad Catolica de Chile | 45 | 2026-04-10 | 2026-08-07 |
| Dietary Strategies for the Treatment of Fibromyalgia in Overweight and Obese Patients Very Low-Calorie Ketogenic Diet, Mediterranean diet, Mediterranean diet enriched by GABA-producing probiotic - Fibromyalgia (FM) | Not applicable | Recruiting | Universita degli Studi di Genova | 90 | 2026-04-10 | 2026-09-30 |
| FAST-M: Prolonged Overnight Fasting and Mediterranean Dietary Intervention for Patients With Multiple Myeloma or Its Precursor Disease Health Coaching, Prolonged Overnight Fasting (POF), Mediterranean Diet - Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance | Not applicable | Recruiting | University of Miami | 120 | 2026-04-07 | 2026-05-01 |
| Phase II, Prospective, Randomized, Proof-of-concept Study to Evaluate the Effects of a Personalized Dietary Intervention in Women With Advanced Gynecologic or Breast Tumors Treated With Antibody-Drug Conjugates (ADCs). Personalised dietary intervention., General recommendations - Gynecologic Cancers, Advanced Breast Cancer | Phase 2 | Recruiting | TNC Nutrición Terapéutica S.L. | 100 | 2026-03-10 | 2026-10-08 |
| Nutritional Intervention for College Students With Depression Mediterranean Diet, Time-Restricted Eating - Depression - Major Depressive Disorder | Not applicable | Recruiting | University of California, San Diego | 30 | 2026-03-01 | 2026-03-24 |
| Efficacy of a Culturally-adapted Mediterranean Diet Intervention on Depression in Relation to the Gut Microbiome Mediterranean Diet - Depression | Not applicable | Not yet recruiting | Chinese University of Hong Kong | 90 | 2026-03-01 | 2026-03-03 |
| Time-Restricted Eating in Combination With a Low Glycaemic Index Diet on Cognitive Function, Biological Ageing and Metabolic Health in Perimenopause and Menopause. Time-Restricted Low-Glycaemic Index Diet - Late-perimenopause, Menopause | Not applicable | Recruiting | University of Nicosia | 72 | 2026-01-17 | 2026-01-30 |
| Evaluation of the Effect of Time-Restricted Feeding and Mediterranean Diet Model in Women With Polycystic Ovary Syndrome Mediterranean diet, intermittent fasting - Polycystic Ovary Syndrome | Not applicable | Completed | Selcuk University | 55 | 2026-01-02 | 2026-04-28 |
| Effects of a Mediterranean Diet With Sequential Cycling and Rowing Exercise on Blood Sugar in Women With Prediabetes or Prediabetes Remission Mediterranean Diet, Supervised Sequential Exercise - Prediabetes | Not applicable | Recruiting | Begüm Yücesoy Güneysu | 30 | 2025-12-15 | 2026-09-15 |
| The Combined Effect of the Mediterranean Diet and Intermittent Fasting on Hypertension Face-to-face nutrition education, Intermittent Fasting Diet, Mediterranean Diet - Hypertension | Not applicable | Recruiting | Nadide Gizem Tarakci Filiz | 48 | 2025-12-13 | 2026-09-25 |
| Mediterranean and Low-Histamine Diets for Pediatric Chronic Spontaneous Urticaria Low-Histamine Diet, Mediterranean Diet - Urticaria Chronic | Not applicable | Recruiting | Saglik Bilimleri Universitesi | 63 | 2025-11-23 | 2026-09-04 |
| Comparative Effects of Mediterranean and DASH Diet on Hepatic Function Dietary guidelines for fatty liver, Mediterranean diet, DASH diet - NAFLD (Nonalcoholic Fatty Liver Disease), Hep A | Not applicable | Completed | University of Lahore | 75 | 2025-11-12 | 2026-06-03 |
| Mediterranean Diet and the Microbiota Gut Brain Axis in Major Depression Mediterranean Diet, Normal hospital diet, dietary coaching - Depression | Not applicable | Not yet recruiting | Medical University of Graz | 108 | 2025-11-01 | 2023-03-14 |
| Gluten-Free vs Mediterranean Diet in Rheumatoid Arthritis Gluten-Free Diet Group, Mediterranean Diet, Control Diet - Rheumatoid Arthritis (RA | Not applicable | Recruiting | Hasan Kalyoncu University | 66 | 2025-10-29 | 2026-06-12 |
| Lifestyle Interventions to Prevent Cognitive Deficits in Subjects With Depressive Symptoms: From Mechanisms to Clinical Practice Mediterranean Diet, Physical Activity, Cognitive Training - Major Depressive Disorder (MDD), Physical Activity | Not applicable | Recruiting | IRCCS Centro San Giovanni di Dio Fatebenefratelli | 120 | 2025-10-01 | 2026-02-11 |
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Obesity (29) · Metabolic Syndrome (13) · Non-alcoholic Fatty Liver Disease (12) · Overweight (12) · Inflammation (11) · Intermittent Fasting (11) · Cardiovascular Diseases (10) · Diabetes Mellitus, Type 2 (9) · Cognitive Dysfunction (8) · Inflammatory Bowel Diseases (8) · Insulin Resistance (7) · Motor Activity (7) · Breast Neoplasms (6) · Depression (5) · Dyslipidemias (5)
Cairo University (5) · Federico II University (4) · Aristotle University Of Thessaloniki (3) · Gangnam Severance Hospital (3) · Harokopio University (3) · Maimónides Biomedical Research Institute of Córdoba (3) · Selcuk University (3) · University of Palermo (3) · Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis (2) · Azienda Ospedaliero-Universitaria Careggi (2) · Hospital Clinic of Barcelona (2) · Pontificia Universidad Catolica de Chile (2) · The Cleveland Clinic (2) · University of California, San Diego (2) · University of Campania Luigi Vanvitelli (2)
United States (34) · Italy (27) · Turkey (Türkiye) (20) · Spain (15) · Egypt (10) · Greece (7) · Chile (4) · Mexico (3) · United Kingdom (3) · Canada (2) · Croatia (2) · Cyprus (2) · Israel (2) · Netherlands (2) · South Korea (2)
Alessandro Casini, MD (2) · Iris Dotan, MD (2) · Amber S. Kleckner, PhD (1) · Amy W Willis, MS, RD (1) · Andrea Hinojosa Azaola, MD (1) · Andriana C Kaliora, PhD (1) · Angela G Fleischman, MD PhD (1) · Angela Rivellese, Professor (1) · Angela Zivkovic, PhD (1) · Anna M Jagielska, MD, PhD (1) · Annamaria Colao, Prof (1) · Anne Kenny, MD (1) · Anne Marie Minihane (1)
PMID 27472878, PMID 31547562, PMID 31802059, PMID 10527182, PMID 10593347, PMID 11282917, PMID 12195709, PMID 12550060, PMID 15383514, PMID 15459601, PMID 15853597, PMID 16481154, PMID 17125535, PMID 17875948, PMID 18695075, PMID 19176282, PMID 19321572, PMID 19383731, PMID 19633906, PMID 19797502, PMID 19843703, PMID 19939653, PMID 20218755, PMID 20603626, PMID 20708148, PMID 20810975, PMID 20826628, PMID 20921963, PMID 22022345, PMID 22102897, PMID 22449789, PMID 22932232, PMID 23165570, PMID 23388669, PMID 24146165, PMID 24312178, PMID 24322653, PMID 24722497, PMID 24783018, PMID 25231836, PMID 25636808, PMID 26474775, PMID 26505825, PMID 26740638, PMID 26890214, PMID 27064675, PMID 27095446, PMID 27145958, PMID 27352954, PMID 27440084
1DP3DK113358-01 (1), 2015 (1), P30AG028740 (1), P30AG035982 (1), P30DK117469 (1), R01AG060157 (1), R01HL076151 (1), R35HL155670 (1)