7 completed, 1 not yet recruiting, 1 unknown. 9 Phase 2, 5 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 7, Not yet recruiting 1, Unknown 1 |
| Phase 3 | 5 | Completed 5 |
| Phase 1 | 1 | Completed 1 |
Follow mecobalamin: new trials by email Literature Review of mecobalamin trials Research Report on mecobalamin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multicenter RCT of Eye-Brain Imaging in Diabetes Neurovascular Coupling hypoglycemic treatment, Tangshen'an Granules, Ginkgo Leaf Tablets - Diabetes Mellitus, Diabetic Retinopathy | Phase 2 | Not yet recruiting | Hejiang Ye | 160 | 2026-01-01 | 2025-09-26 |
| Evaluation of the Efficiacy of Mecobalamine in the Treatment of Long-term Pain in Women Diagnosed With Fibromyalgia Mecobalamin 5 MG, Placebo Comparator : NaCl 9 mg/ml - Fibromyalgia | Phase 1 / Phase 2 | Completed | Linnaeus University | 40 | 2019-02-06 | 2024-12-18 |
| A Randomized Controlled Trial of Mecobalamin Injection and Tablet Treatment Efficacy on Mild to Moderate Diabetic Peripheral Neuropathy methylcobalamin - Diabetic Neuropathies | Phase 2 | Unknown | Peking University Third Hospital | 30 | 2017-12-25 | 2020-05-04 |
| Lung Function in Patients With Early Type 2 Diabetes Mellitus Calcium Dobesilate, Xuefuzhuyu Decoction, Xuefuzhuyu Decoction & Calcium dobesilate - Type 2 Diabetes Mellitus, Pulmonary Function | Phase 2 / Phase 3 | Completed | Liaoning University of Traditional Chinese Medicine | 200 | 2014-07-21 | 2017-05-30 |
| Trial of Methyl B12 on Behavioral and Metabolic Measures in Children With Autism Methyl B12, Placebo - Autistic Disorder | Phase 2 / Phase 3 | Completed | University of California, San Francisco | 57 | 2010-01-01 | 2017-02-24 |
| Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total Gastrectomy mecobalamin - Vitamin B12 Deficiency | Phase 2 | Completed | Yonsei University | 30 | 2008-04-01 | 2012-07-19 |
| A Long-Term Study in Patients With Amyotrophic Lateral Sclerosis (ALS) E0302 (mecobalamin) - Amyotrophic Lateral Sclerosis (ALS) | Phase 2 / Phase 3 | Completed | Eisai Co., Ltd. | 135 | 2008-02-01 | 2023-06-18 |
| A Study in Patients With Amyotrophic Lateral Sclerosis (ALS) E0302 (mecobalamin), Placebo - Amyotrophic Lateral Sclerosis (ALS) | Phase 2 / Phase 3 | Completed | Eisai Co., Ltd. | 373 | 2007-04-01 | 2023-06-18 |
| Efficacy Study of Subcutaneous Methyl-B12 in Children With Autism methylcobalamin, saline placebo - Autistic Disorder | Phase 2 / Phase 3 | Completed | University of California, San Francisco | 30 | 2005-07-01 | 2019-10-09 |
Amyotrophic Lateral Sclerosis (2) · Autistic Disorder (2) · Muscular Atrophy (2) · Child Development Disorders, Pervasive (1) · Chronic Pain (1) · Cognitive Dysfunction (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Neuropathies (1) · Diabetic Retinopathy (1) · Fibromyalgia (1) · Stomach Neoplasms (1) · Vitamin B 12 Deficiency (1)
Eisai Co., Ltd. (2) · University of California, San Francisco (2) · Hejiang Ye (1) · Liaoning University of Traditional Chinese Medicine (1) · Linnaeus University (1) · Peking University Third Hospital (1) · Yonsei University (1)
China (2) · Japan (2) · United States (2) · South Korea (1) · Sweden (1)
Kazunori Saeki (2) · Carina Elmqvist, Ass prof (1) · Robert L Hendren, D.O. (1) · Robert L. Hendren, DO (1) · Woo Jin Hyung, Ph.D (1) · Xiao-lin Jiang (1)
PMID 25982504, PMID 26889605, PMID 30636701, PMID 34282267, PMID 36997252, PMID 41475066