140 completed, 23 unknown, 11 not yet recruiting, 9 recruiting. 194 Not applicable, 6 Phase 2, 3 Phase 1, 3 Phase 3, 1 Phase 4.
Follow this drug Literature Review of Manual Therapy trials Research Report on Manual Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Proactively Intervening On Early Cranial Nerve Injury As A Delayed Sequela Of Oropharyngeal Cancer: A Randomized Feasibility Clinical Trial For Pro-Habilitation (proNERVE RCT) Prednisone, Ajovy, Manual Therapy - Cranial Nerve Injury, Oropharyngeal Cancer | Phase 1 | Not yet recruiting | M.D. Anderson Cancer Center | 48 | 2027-03-01 | 2026-09-21 |
| Multimodal Therapy for Somatosensory Tinnitus Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support - Ear Noise, Tinnitus, Noise Induced | Not applicable | Not yet recruiting | Charles University, Czech Republic | 160 | 2027-01-01 | 2026-03-12 |
| Acupuncture for Heel Pain Syndrome Acupuncture, Manual Therapy, Sham Acupuncture - Heel Pain Syndrome | Not applicable | Not yet recruiting | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine | 150 | 2026-10-15 | 2026-10-14 |
| Dry Needling or Percutaneous Electrolysis for Managing Myofascial Trigger Points? Dry needling, Percutaneous electrolysis (Low Intensity - Long Time), Manual therapy - Shoulder Pain | Not applicable | Not yet recruiting | Universidad Complutense de Madrid | 60 | 2026-09-15 | 2026-09-09 |
| Lumbar Extension Strengthening in Addition to Manual Therapy and Exercise for Chronic Low Back Pain Standard Physical Therapy, Lumbar Extensor Strengthening plus Standard Physical Therapy - Chronic Low Back Pain (CLBP) | Not applicable | Enrolling by invitation | Brooke Army Medical Center | 60 | 2026-08-03 | 2026-07-22 |
| Manual Intervention and Congenital Hip Dysplasia in Infants Manual therapy - Developmental Dysplasia of the Hip (DDH), Congenital Hip Dysplasia | Not applicable | Not yet recruiting | Université de Sherbrooke | 30 | 2026-08-01 | 2026-08-11 |
| Investigation of the Effect of Thoracic Manipulation and Classical Massage on Pain, Flexibility and Sleep Quality Classical Massage, Manual therapy - MECHANICAL BACK PAIN, Sleep Quality | Not applicable | Enrolling by invitation | Ayşe BAŞAYAN | 60 | 2026-04-01 | 2026-04-09 |
| Effectiveness of Instrumental Assisted Soft Tissue Mobilization Versus Conventional Treatment on Administrative Staff for Text Neck Syndrome progressive isometric exercises, Instrument-Assisted Soft Tissue Mobilization - Text Neck Syndrome | Not applicable | Active not recruiting | University of Health Sciences Lahore | 48 | 2026-02-25 | 2026-03-10 |
| Temporomandibular Joints Mobility and Head Posture: Influence of Manual Therapy and Exercises in Dental Patients. Manual therapy - Temporomandibular Joint Disorders | Not applicable | Not yet recruiting | The Jerzy Kukuczka Academy of Physical Education in Katowice | 100 | 2026-01-20 | 2025-12-22 |
| Efficacy of Non-invasive Neuromodulation Treatments for COVID-19 Sequelae Non invasive neuromodulation therapy, Manual therapy, Placebo with non invasive neuromodulation - Covid-19 Recurrent | Not applicable | Not yet recruiting | Clinica Gema Leon | 104 | 2026-01-01 | 2025-09-18 |
| Psychological Predictors of Pain and Disability in Patients With Chronic Low Back Pain After Manual Therapy Manual therapy, Manual therapy plus Pain Neuroscience Education - Low Back Pain, Disability Physical | Not applicable | Enrolling by invitation | University of Thessaly | 60 | 2025-12-10 | 2026-02-18 |
| Comparison Interventions on Kinetic and Kinematic Parameters Manual therapy, Placebo, Exercise - Young Football Players, Ankle Sprain Prevention | Not applicable | Enrolling by invitation | Medical University of Gdansk | 45 | 2025-11-20 | 2026-01-08 |
| Effects of Graston Technique Versus Soft Tissue Release on Neck Pain and Range of Motion. Graston Technique, Manual Soft Tissue Release - Tension Neck Syndrome | Not applicable | Completed | Green International University | 40 | 2025-11-02 | 2026-05-22 |
| Pre-Surgery Rehab for a Child With Humeral Head and Shaft Deformity: A Case Report Transcutaneous Electrical Nerve Stimulation, Low-Level Laser Therapy, Manual Therapy - Osteomyelitis Chronic, Bone Defects | Not applicable | Completed | Cairo University | 1 | 2025-10-01 | 2025-12-15 |
| Manual Therapy on Lateral Elbow Pain Manual Therapy, Sham Manual Therapy - Tennis Elbow | Not applicable | Active not recruiting | University of La Laguna | 160 | 2025-10-01 | 2026-03-10 |
| Workplace Exercise Therapy With or Without Manual Therapy in Chronic Spinal Pain Exercise therapy, Manual Therapy, Sham Manual Therapy - Back Pain, Neck Pain | Not applicable | Enrolling by invitation | Catholic University of Murcia | 60 | 2025-09-29 | 2026-07-21 |
| Comparison of Different Rehabilitation Approaches in Chronic Neck Pain Manual Therapy, Instrument-Assisted Soft Tissue Mobilization (IASTM) - Neck Pain Musculoskeletal | Not applicable | Completed | Atlas University | 24 | 2025-09-01 | 2026-02-09 |
| Effectiveness of Stanley Paris Manual Therapy vs. Conventional Physiotherapy in Reducing Pain and Improving Function in Grade II Knee Osteoarthritis Hands-on manual therapy including joint mobilization, soft tissue and neural mobilization, and movement retraining based on the Stanley Paris Concept., Conventional Physiotherapy Standard physiotherapy care including electrotherapy modalities (TENS, ultrasound), strengthening, flexibility, and balance training exercises. - Osteoarthritis (OA) of the Knee | Not applicable | Completed | Ibadat International University, Islamabad | 50 | 2025-08-05 | 2026-03-24 |
| Effects Exercises in Temporomandibular Joint Disorders on Pain, Joint and Tongue Functions Exercise, Manual therapy - TMD, TMD/Orofacial Pain | Not applicable | Recruiting | Tayfun ISIK | 48 | 2025-06-19 | 2025-12-26 |
| Shoulder Manipulation in Volleyball Players Manual therapy, Placebo, Exercise - Manual Therapy, Manipulation | Not applicable | Recruiting | Medical University of Gdansk | 12 | 2025-05-19 | 2025-05-28 |
Showing 20 of 211. Sign in to see all of them.
Neck Pain (25) · Low Back Pain (21) · Pain (21) · Motor Activity (14) · Temporomandibular Joint Disorders (12) · Hemophilia A (8) · Shoulder Pain (7) · Back Pain (6) · Bruxism (6) · Osteoarthritis, Knee (6) · Shoulder Impingement Syndrome (6) · Joint Diseases (5) · Tension-Type Headache (5) · Chronic Pain (4) · Kinesiophobia (4)
University of Valencia (12) · Cairo University (7) · Medical University of Gdansk (6) · Universidad Rey Juan Carlos (5) · Investigación en Hemofilia y Fisioterapia (4) · Istanbul Medipol University Hospital (4) · Duke University (3) · Hacettepe University (3) · Universidad de Granada (3) · Universidade Federal de Sao Carlos (3) · University of Alcala (3) · University of Jaén (3) · Université du Québec à Trois-Rivières (3) · Bahçeşehir University (2) · Bartın Unıversity (2)
Spain (61) · Turkey (Türkiye) (34) · United States (28) · Brazil (12) · Egypt (10) · Poland (9) · Pakistan (7) · United Kingdom (6) · Canada (4) · China (4) · Saudi Arabia (3) · Czechia (2) · France (2) · Greece (2) · Italy (2)
Alexander Achalandabaso, PhD (2) · Muhammad Osama, PhD* (2) · Abd ELkhalek Mansour Ahmed, MSC, DPT (1) · Abdul Ghafoor Sajjad, Phd* (1) · Al Raza, CST (1) · Alena Kobesova, MD, PhD (1) · Alexander Achalandabaso (1)
PMID 11074683, PMID 11295901, PMID 12763442, PMID 15132324, PMID 15365964, PMID 16182025, PMID 16472338, PMID 16691091, PMID 16911795, PMID 17257237, PMID 17366957, PMID 17368075, PMID 18827326, PMID 18923311, PMID 18984549, PMID 19028251, PMID 19130648, PMID 19209478, PMID 19329049, PMID 19345785, PMID 19797305, PMID 20430685, PMID 20634268, PMID 20647241, PMID 20710088, PMID 20801246, PMID 20850038, PMID 20958995, PMID 21234327, PMID 21419363, PMID 21570892, PMID 21796089, PMID 21943614, PMID 22021870, PMID 22196427, PMID 22546751, PMID 22863643, PMID 22923162, PMID 23026869, PMID 23115475, PMID 23684553, PMID 24378321, PMID 24700500, PMID 25089860, PMID 25213604, PMID 25246239, PMID 25357218, PMID 25440210, PMID 25780258, PMID 25831430
2015 (1), R21CA226200 (1)