24 completed. 24 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 24 | Completed 24 |
| Phase 1 | 1 | Completed 1 |
Follow Lupron: new trials by email Literature Review of Lupron trials Research Report on Lupron
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model Leuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone - Perinatal Depression, Post Partum Depression | Phase 2 | Completed | University of North Carolina, Chapel Hill | 23 | 2020-01-02 | 2023-08-25 |
| A Pilot Study of 5-AZA and ATRA for Prostate Cancer With PSA-only Recurrence After Local Treatment 5-Azacitidine, all trans retinoic acid, Lupron - Prostatic Neoplasms, Prostate Neoplasms | Phase 2 | Completed | Icahn School of Medicine at Mount Sinai | 14 | 2018-08-20 | 2024-04-30 |
| Neoadjuvant And Adjuvant Abiraterone Acetate + Apalutamide Prostate Cancer Undergoing Prostatectomy Apalutamide, Leuprolide, Prednisone - Prostate Cancer | Phase 2 | Completed | Dana-Farber Cancer Institute | 118 | 2016-10-19 | 2025-06-13 |
| Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer Leuprolide acetate, Apalutamide, Radical prostatectomy - Prostate Cancer | Phase 2 | Completed | Case Comprehensive Cancer Center | 54 | 2016-10-17 | 2022-06-21 |
| Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer Enzalutamide, leuprolide acetate, goserelin acetate - Adenocarcinoma of the Prostate, Recurrent Prostate Cancer | Phase 2 | Completed | University of Colorado, Denver | 19 | 2015-11-11 | 2025-05-11 |
| Enzalutamide and Hormone Therapy Before, During, and After Radiation for High Risk Localized Prostate Cancer Enzalutamide, Leuprolide acetate, radiation - Prostate Cancer | Phase 2 | Completed | University of Texas Southwestern Medical Center | 7 | 2014-05-01 | 2020-10-12 |
| LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate Cancer enzalutamide, bicalutamide, orchiectomy - Adenocarcinoma of the Prostate, Recurrent Prostate Cancer | Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 71 | 2014-05-01 | 2023-05-10 |
| Phase II Study of DCVAC/PCa Added to Hormone Therapy for Men With Metastatic Prostate Cancer Dendritic Cells DCVAC/PCa, Leuprolide acetate, Goserelin Acetate - Prostate Cancer | Phase 2 | Completed | SOTIO a.s. | 63 | 2012-03-01 | 2017-05-24 |
| Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantation First Allogeneic Bone Marrow Transplant (BMT), Leuprolide, 18F FLT - Myelodysplastic Syndrome, Acute Lymphocytic Leukemia | Phase 2 | Completed | National Cancer Institute (NCI) | 76 | 2011-04-19 | 2021-03-18 |
| Bicalutamide and Goserelin or Leuprolide Acetate With or Without Cixutumumab in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer Bicalutamide, Cixutumumab, Goserelin Acetate - Prostate Adenocarcinoma, Recurrent Prostate Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 211 | 2010-12-01 | 2018-02-26 |
| Abiraterone Prednisone and Hormonal Therapy Before and During Radiation Therapy in Localized Prostate Cancer abiraterone acetate, prednisone, leuprolide acetate - Adenocarcinoma of the Prostate, Stage II Prostate Cancer | Phase 2 | Completed | University of Washington | 24 | 2010-03-01 | 2017-06-06 |
| Extended Endocrine Therapy for Premenopausal Women With Breast Cancer leuprolide, letrozole, zoledronic acid - Breast Cancer | Phase 2 | Completed | Dana-Farber Cancer Institute | 17 | 2009-05-01 | 2016-04-18 |
| Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate Cancer Bicalutamide, Goserelin Acetate, Laboratory Biomarker Analysis - Prostate Adenocarcinoma, Stage I Prostate Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 19 | 2007-11-01 | 2017-10-06 |
| Pazopanib Hydrochloride After Leuprolide Acetate or Goserelin Acetate in Treating Patients With Relapsed Prostate Cancer pazopanib hydrochloride, leuprolide acetate, goserelin acetate - Recurrent Prostate Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 37 | 2006-06-01 | 2016-02-10 |
| Melanoma Vaccine With Peptides and Leuprolide Leuprolide, GP100: 209-217(210M) Peptide, MAGE-3 Peptide - Melanoma | Phase 2 | Completed | M.D. Anderson Cancer Center | 98 | 2005-11-01 | 2019-10-16 |
| Docetaxel, Androgen Ablation, and External-Beam Radiation Therapy in Patients With High-Risk Localized Prostate Cancer docetaxel, leuprolide acetate, radiation therapy - Prostate Cancer | Phase 1 / Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 23 | 2005-08-01 | 2017-06-01 |
| Insulin Resistance and Testosterone in Women metformin, leuprolide injection, placebo pill - Insulin Resistance, Postmenopause | Phase 2 | Completed | University of Pennsylvania | 35 | 2005-07-01 | 2019-05-23 |
| Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer Bicalutamide, Flutamide, Goserelin Acetate - Prostate Adenocarcinoma, Prostate Carcinoma | Phase 2 | Completed | Mayo Clinic | 112 | 2004-06-01 | 2017-05-15 |
| Hormonal Ablation, Imatinib Mesylate and Docetaxel for Patients With Prostate Cancer Docetaxel, Imatinib Mesylate, Leuprolide - Prostate Cancer | Phase 2 | Completed | M.D. Anderson Cancer Center | 39 | 2003-06-01 | 2015-04-28 |
| Zometa on Bone Mineral Density in Prostate Cancer Patients Undergoing Androgen Ablation Therapy Zometa, zometa - Prostate Cancer | Phase 2 | Completed | University of Wisconsin, Madison | 44 | 2003-04-01 | 2019-11-26 |
Showing 20 of 24. Sign in to see all of them.
Prostatic Neoplasms (17) · Depression, Postpartum (2) · Breast Neoplasms (1) · Depression (1) · Eye Neoplasms (1) · Insulin Resistance (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Acute (1) · Leukemia, Myelomonocytic, Chronic (1) · Melanoma (1) · Mental Disorders (1) · Mood Disorders (1) · Myelodysplastic Syndromes (1) · Neoplasms (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
National Cancer Institute (NCI) (4) · University of Washington (3) · Dana-Farber Cancer Institute (2) · M.D. Anderson Cancer Center (2) · Barbara Ann Karmanos Cancer Institute (1) · Case Comprehensive Cancer Center (1) · Icahn School of Medicine at Mount Sinai (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · National Institute of Mental Health (NIMH) (1) · SOTIO a.s. (1) · UNC Lineberger Comprehensive Cancer Center (1) · University of Colorado, Denver (1) · University of North Carolina, Chapel Hill (1) · University of Pennsylvania (1)
United States (23) · Canada (1) · Czechia (1)
Celestia Higano, MD (2) · Ann Partridge, MD (1) · Anne R. Cappola, MD, ScM (1) · Christopher G Kanakry, M.D. (1) · Crystal E Schiller, PhD (1) · Douglas McNeel, MD (1) · Edwin Posadas (1) · Elisabeth Heath, M.D. (1) · Elizabeth Kessler, MD (1) · Eugene Kwon (1) · Evan Yu (1) · Howard Scher, MD (1) · Kevin D Courtney, MD, PhD (1) · Mary-Ellen Taplin, MD (1) · Moshe Ornstein, MD (1)
PMID 19012911, PMID 22006050, PMID 25242417, PMID 25847934, PMID 29248669, PMID 33496795, PMID 33683939, PMID 38161319, PMID 39074346, PMID 39670843
K23AG019161 (1), N01CM62201 (1), N01CM62205 (1), N01CM62206 (1), P30CA008748 (1), P30CA015083 (1), P30CA015704 (1), P30CA022453 (1), P30DK019525 (1), R21MH119615 (1), U10CA032102 (1)