8 completed, 2 not yet recruiting, 2 terminated, 2 unknown. 5 Phase 3, 3 Not applicable, 2 Phase 2, 2 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 3, Not yet recruiting 1, Withdrawn 1 |
| Not applicable | 3 | Completed 1, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Levothyroxin: new trials by email Literature Review of Levothyroxin trials Research Report on Levothyroxin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Necessity of TSH Suppression Therapy in Active Surveillance for Thyroid Cancer Patients. Levothyroxin - Thyroid Cancer, Papillary Thyroid Carcinoma | Not applicable | Not yet recruiting | National Cancer Center, Korea | 578 | 2025-06-02 | 2025-05-14 |
| LIGHT Trial: Levothyroxine for Gestational Hypothyroidism in Recurrent Pregnancy Loss Levothyroxin, Placebo - Abortion, Habitual | Phase 3 | Not yet recruiting | Women's Hospital School Of Medicine Zhejiang University | 200 | 2025-06-01 | 2025-06-04 |
| Vitamin D & Levothyroxine Combination Versus Levothyroxine on Lipid Profile in Hypothyroidism Vitamin D, Levothyroxin - Hypothyroidism Primary, Lipid Disorder | Phase 3 | Completed | King Edward Medical University | 62 | 2024-03-01 | 2025-03-11 |
| Correlation Between Levothyroxine and Blood Th17/Treg in Pregnant Women With Normal-high TSH and Positive TPOAb Levothyroxin - Pregnancy Related, Thyroid Stimulating; Hormone, C | Terminated | Third Affiliated Hospital of Zhengzhou University | 64 | 2022-04-06 | 2024-07-30 | |
| Final Height in Patients With CH Diagnosed by the Screening Levothyroxin - Congenital Hypothyroidism | Unknown | Ain Shams University | 60 | 2021-11-02 | 2021-10-05 | |
| Levothyroxine-sodium Bioequivalence Trial With Oral Single Dose Administration Levothyroxin - Healthy | Phase 1 | Completed | Berlin-Chemie AG Menarini Group | 132 | 2021-10-22 | 2024-08-09 |
| The Prevalence and Risk Factors for Thyroid Dysfunction in Pregnant Women in Taiwan PTU 50 MG Oral Tablet, Levothyroxin - Thyroid Disease Pregnancy | Unknown | Chang Gung Memorial Hospital | 2000 | 2021-07-16 | 2021-08-16 | |
| Study of Thyroid Hormones in Prematures thryoid hormone T4 + oral potassium iodide (KI) for 42 days, D5W - 5% dextrose water - Transient Hypothyroxinemia of Prematurity (THOP) | Phase 3 | Withdrawn | New York Medical College | 2020-07-01 | 2019-04-24 | |
| Identification of Non-responders to Levothyroxine Therapy Levothyroxin, Liothyronine - Hypothyroidism, Biomarkers | Phase 2 | Completed | Oslo University Hospital | 69 | 2018-08-14 | 2021-03-17 |
| Efficacy of Low Dose Levothyroxine During Pregnancy levothyroxin - Euthyroid Females | Phase 3 | Completed | Ain Shams University | 180 | 2017-05-01 | 2021-10-07 |
| Combined Replacement Therapy With Levothyroxine and Liothyronine in Thyroidectomized Patients Liothyronine, Levothyroxin, Placebos - Hypothyroidism | Phase 2 / Phase 3 | Completed | Azienda USL Modena | 160 | 2017-03-14 | 2023-04-21 |
| The Effect of Thyroid Hormone Therapy on Muscle Mass and Function in Older Adults With Subclinical Hypothyroidism Levothyroxin, Placebo - Subclinical Hypothyroidism, Sarcopenia | Phase 4 | Completed | Insel Gruppe AG, University Hospital Bern | 322 | 2014-05-01 | 2023-05-18 |
| Interaction Between Levothyroxine and Probiotics in Hypothyroid Patients a mixture of highly charged Lactobacilli and Bifidobacteria (VSL#3®), levothyroxin - Hypothyroidism | Not applicable | Completed | Azienda USL Modena | 80 | 2014-01-01 | 2017-03-30 |
| Influence of Initial Levothyroxine Dose on Neurodevelopmental and Growth Outcomes in Congenital Hypothyroidism Levothyroxin - Congenital Hypothyroidism | Phase 4 | Completed | Federico II University | 72 | 2011-05-01 | 2022-05-12 |
| Insulin Sensitivity and Metabolism Before and After Treatment in Patients With Hypothyroidism Levothyroxin - Hypothyroidism | Not applicable | Terminated | University of Aarhus | 2010-01-01 | 2010-10-26 |
Hypothyroidism (5) · Congenital Hypothyroidism (2) · Abortion, Habitual (1) · Cerebral Palsy (1) · Dyslipidemias (1) · Endocrine System Diseases (1) · Fatty Liver (1) · Insulin Resistance (1) · Lipid Metabolism Disorders (1) · Sarcopenia (1) · Thyroid Cancer, Papillary (1) · Thyroid Diseases (1) · Thyroid Neoplasms (1)
Ain Shams University (2) · Azienda USL Modena (2) · Berlin-Chemie AG Menarini Group (1) · Chang Gung Memorial Hospital (1) · Federico II University (1) · Insel Gruppe AG, University Hospital Bern (1) · King Edward Medical University (1) · National Cancer Center, Korea (1) · New York Medical College (1) · Oslo University Hospital (1) · Third Affiliated Hospital of Zhengzhou University (1) · University of Aarhus (1) · Women's Hospital School Of Medicine Zhejiang University (1)
China (2) · Egypt (2) · Denmark (1) · Germany (1) · Italy (1) · Netherlands (1) · Norway (1) · Pakistan (1) · Switzerland (1) · Taiwan (1) · United States (1)
Edmund F La Gamma, MD (1) · Erik Fink Eriksen, Professor (1) · Eun Kyung Lee (1) · Mariacarolina Salerno, Professor (1) · Minjoo Kim (1) · Nicolas Rodondi, MD MAS (1) · Qiong Luo, Ph.D. (1) · Rana Mahmoud, PhD (1) · Wessam Mouharram, PhD (1) · Xin Tian (1) · Yanjie Ban (1) · Young Joo Park (1)
PMID 11580992, PMID 16205094, PMID 17433800, PMID 17932107, PMID 19581264, PMID 25036648, PMID 28548569, PMID 28853052, PMID 29184537, PMID 31350727, PMID 34867829, PMID 35273566, PMID 35572853, PMID 36133316, PMID 36721961, PMID 5491878, PMID 7639544, PMID 9497870
2017 (1)