16 completed. 16 Phase 2, 3 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 16 |
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
Follow IVIG: new trials by email Literature Review of IVIG trials Research Report on IVIG
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IVIG Versus Plasmapheresis in the Treatment of Guillian Barrie Syndrome Patients plasmapheresis device, Intravenous immunoglobulin - Guillain-Barre Syndrome | Phase 2 / Phase 3 | Completed | Assiut University | 81 | 2021-09-01 | 2023-04-06 |
| Intravenous Immunoglobulin and Prednisolone for RPL After ART. Human Intravenous Immunoglobulins, (Privigen (R), CLS Behring), Prednisolone Tablets, Human Albumin Solution - Habitual Abortion, Recurrent Pregnancy Loss | Phase 2 | Completed | Aalborg University Hospital | 80 | 2021-01-28 | 2025-11-24 |
| Open-label Trial of IVIG in Children With PANS Privigen Injectable Product (Intravenous Immunoglobulin) - PANS Pediatric Acute-Onset Neuropsychiatric Syndrome | Phase 2 | Completed | Göteborg University | 17 | 2021-01-12 | 2026-03-06 |
| IVIG (Gamunex-C) Treatment Study for POTS Subjects IVIG, Albumin - Postural Tachycardia Syndrome | Phase 1 / Phase 2 | Completed | University of Texas Southwestern Medical Center | 30 | 2018-10-29 | 2024-09-19 |
| Immunomodulatory Effects of IVIg on Pregnancy Rate of Patient With Recurrent Pregnancy Loss IVIg - Recurrent Pregnancy Loss | Phase 2 | Completed | Tabriz University of Medical Sciences | 50 | 2016-09-20 | 2018-09-17 |
| Immunomodulatory Effects of IVIg on Pregnancy Rate of Patient With Recurrent Implantation Failure IVIg - Recurrent Implantation Failure | Phase 2 | Completed | Tabriz University of Medical Sciences | 50 | 2016-07-20 | 2018-09-17 |
| A Safety Study of Tocilizumab to Improve Transplant Rates in Highly Sensitized Patients Awaiting Kidney Transplantation Tocilizumab, Intravenous Immunoglobulin - End Stage Renal Disease (ESRD) | Phase 1 / Phase 2 | Completed | Cedars-Sinai Medical Center | 10 | 2012-06-01 | 2016-08-25 |
| Safety and Efficacy of Intravenous Immune Globulin in Treating Spinocerebellar Ataxia IVIG - Spinocerebellar Ataxia | Phase 2 | Completed | University of South Florida | 5 | 2011-08-01 | 2013-07-23 |
| Study of Octagam (Intravenous Immunoglobulin [IVIG]) 10% on the Treatment of Mild to Moderate Alzheimer's Disease Placebo, octagam 10% - Alzheimer's Disease | Phase 2 | Completed | Octapharma | 58 | 2009-02-01 | 2014-05-05 |
| A Trial of the Pharmacokinetics, Safety, and Tolerability of Subcutaneous Gamunex® in Primary Immunodeficiency Immune Globulin Intravenous (Human) - Immunologic Deficiency Syndrome | Phase 2 | Completed | Grifols Therapeutics LLC | 35 | 2006-11-01 | 2015-04-20 |
| Intravenous Immunoglobulin (IVIG) in Lung Transplantation IVIG, Placebo - Hypogammaglobulinemia, Lung Transplantation | Phase 2 | Completed | Columbia University | 11 | 2005-06-01 | 2019-03-05 |
| Use of Immune Globulin Intravenous (Human) To Treat Age-Related Macular Degeneration Immune Globulin Intravenous [Human], 10% Caprylate/Chromatography Purified, Albumin (Human) 25%, United States Pharmacopeia (USP) - Macular Degeneration | Phase 2 | Completed | Grifols Therapeutics LLC | 96 | 2004-01-01 | 2016-03-21 |
| Post-Poliosyndrome Treated With Intravenous Immunoglobulin (IvIg) IvIg - Post-Polio Syndrome | Phase 2 / Phase 3 | Completed | Haukeland University Hospital | 40 | 2003-08-01 | 2005-12-13 |
| Rapid Infusion Of Immune Globulin Intravenous (IGIV) In Patients With ITP Immune Globulin IV [Human], 10% Caprylate/Chromatography Purified - Purpura, Thrombocytopenic, Idiopathic | Phase 2 | Completed | Grifols Therapeutics LLC | 8 | 2003-07-01 | 2016-04-27 |
| Immune Globulin Intravenous (IGIV) To Treat Relapsing, Remitting Multiple Sclerosis Immune Globulin IV [Human], 10% Caprylate/Chromatography Purified, Albumin (Human) 25%, United States Pharmacopeia (USP) - Multiple Sclerosis, Relapsing-Remitting | Phase 2 | Completed | Grifols Therapeutics LLC | 128 | 2002-12-01 | 2016-04-27 |
| Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection IVIG, Placebo - Infant, Newborn, Infant, Low Birth Weight | Phase 2 / Phase 3 | Completed | NICHD Neonatal Research Network | 2416 | 1988-01-01 | 2019-03-22 |
Abortion, Habitual (1) · Abortion, Spontaneous (1) · Agammaglobulinemia (1) · Alzheimer Disease (1) · Guillain-Barre Syndrome (1) · Immunologic Deficiency Syndromes (1) · Kidney Failure, Chronic (1) · Macular Degeneration (1) · Meningitis (1) · Multiple Sclerosis, Relapsing-Remitting (1) · Pediatric acute-onset neuropsychiatric syndrome (1) · Postpoliomyelitis Syndrome (1) · Postural Orthostatic Tachycardia Syndrome (1) · Premature Birth (1) · Primary Immunodeficiency Diseases (1)
Grifols Therapeutics LLC (4) · Tabriz University of Medical Sciences (2) · Aalborg University Hospital (1) · Assiut University (1) · Cedars-Sinai Medical Center (1) · Columbia University (1) · Göteborg University (1) · Haukeland University Hospital (1) · NICHD Neonatal Research Network (1) · Octapharma (1) · University of South Florida (1) · University of Texas Southwestern Medical Center (1)
United States (9) · Canada (2) · Germany (2) · Iran (2) · Sweden (2) · Austria (1) · Czechia (1) · Denmark (1) · Egypt (1) · Greece (1) · Hungary (1) · Israel (1) · Poland (1) · Slovakia (1) · United Kingdom (1)
Mehdi Yousefi, Immunologist (2) · Mohammad Nouri, Ph.D (2) · Avroy A. Fanaroff, MD (1) · Charles R. Bauer, MD (1) · Christopher Gillberg, Professor (1) · Elisabeth Farbu, MD, PhD (1) · Elizabeth C. Wright, PhD (1) · Fred D Lublin, MD (1) · James Bussel, MD (1) · Jerold F. Lucey, MD (1) · Jon E. Tyson, MD MPH (1) · Joseph B. Philips, MD (1) · Ole B Christiansen (1) · Richard Brunner, MD (1) · Ronald L. Poland, MD (1)
PMID 12765346, PMID 17166218, PMID 19710204, PMID 19819893, PMID 21095154, PMID 22889462, PMID 24628478, PMID 18645164, PMID 23375965, PMID 25090414, PMID 35933358, PMID 36137638, PMID 41263919, PMID 8133853, PMID 9686724
U01HD019897 (1), U10HD021364 (1), U10HD021373 (1), U10HD021385 (1), U10HD021397 (1), U10HD021415 (1)